GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0038061 ! non-canonical NF-kappaB signal transduction
name: non-canonical NF-kappaB signal transduction
namespace: biological_process
def: "An intracellular signaling cassette characterized by the NIK-dependent processing and activation of NF-kappaB. Begins with activation of the NF-kappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-kappa B2 protein (p100) leading to p100 processing and release of an active NF-kappaB (p52). The non-canonical NF-kappaB signaling pathway is generally activated by ligands of the TNF receptor superfamily, including lymphotoxin beta (LTB), CD40, OX40, RANK, TWEAK and B cell-activating factor (BAFF)." [GOC:bf, GOC:mg2, GOC:signaling, GOC:vs, PMID:11239468, PMID:15140882, PMID:34659217]
synonym: "NF-kappaB cascade" BROAD []
synonym: "NIK-IKK kinase cascade" EXACT [GOC:rph, PMID:10094049, PMID:10581243, PMID:9244310]
synonym: "NIK-IKK signaling pathway" EXACT [GOC:rph, PMID:10094049, PMID:10581243, PMID:9244310]
synonym: "NIK-IKK-alpha cascade" EXACT [GOC:rph, PMID:10094049, PMID:10581243, PMID:9244310]
synonym: "NIK/NF-kappaB cascade" EXACT [GOC:signaling]
synonym: "NIK/NF-kappaB signal transduction" EXACT [GOC:signaling]
synonym: "NIK/NF-kappaB signaling" EXACT []
synonym: "non-canonical NF-KB signaling" EXACT [PMID:21173796]
synonym: "noncanonical NF-kappaB signaling" EXACT [PMID:20501935]
synonym: "noncanonical nuclear factor kappaB (NF-kappaB) pathway" EXACT [PMID:20501935]
synonym: "p52-dependent NF-kappaB signaling" NARROW [PMID:18292232]
is_a: GO:0141124 ! intracellular signaling cassette
AmiGO
<GOterm>GO:0038061</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
Child Terms
This category has the following 3 subcategories, out of 3 total.
Pages in category "GO:0038061 ! non-canonical NF-kappaB signal transduction"
This category contains only the following page.