CHICK:GBLP

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	GNB2L1
Protein Name(s)	Guanine nucleotide-binding protein subunit beta-2-like 1 Guanine nucleotide-binding protein subunit beta-like protein 12.3 Receptor for activated C kinase Receptor of activated protein kinase C 1 RACK1
External Links
UniProt	P63247
EMBL	M24193 AY393848 AY694127 AB268588
PIR	A33928
RefSeq	NP_001004378.1
UniGene	Gga.7066
ProteinModelPortal	P63247
SMR	P63247
BioGrid	678470
MINT	MINT-92357
STRING	9031.ENSGALP00000000170
PaxDb	P63247
PRIDE	P63247
Ensembl	ENSGALT00000000171
GeneID	417044
KEGG	gga:417044
CTD	10399
eggNOG	COG2319
GeneTree	ENSGT00800000124124
HOGENOM	HOG000091643
HOVERGEN	HBG000277
InParanoid	P63247
KO	K14753
OMA	QYGYPKR
PhylomeDB	P63247
NextBio	20820423
PRO	PR:P63247
Proteomes	UP000000539
GO	GO:0005737 GO:0005829 GO:0030425 GO:0070062 GO:1990630 GO:0030496 GO:0005739 GO:0043025 GO:0005634 GO:0048471 GO:0001891 GO:0008656 GO:0008200 GO:0044822 GO:0030292 GO:0035591 GO:0071333 GO:0030308 GO:0010629 GO:1903208 GO:0033137 GO:0050765 GO:0051898 GO:0030178 GO:0030822 GO:0030335 GO:0051343 GO:2000543 GO:0043547 GO:2001244 GO:0051901 GO:0032436 GO:0032464 GO:0001934 GO:0051726 GO:0051302 GO:2000114 GO:0032880 GO:0007165
Gene3D	2.130.10.10
InterPro	IPR020472 IPR015943 IPR001680 IPR019775 IPR017986
Pfam	PF00400
PRINTS	PR00320
SMART	SM00320
SUPFAM	SSF50978
PROSITE	PS00678 PS50082 PS50294

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0043022	ribosome binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63244	F	Seeded From UniProt	complete
involved_in	GO:0072344	rescue of stalled ribosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63244	P	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63244	P	Seeded From UniProt	complete
involved_in	GO:2000543	positive regulation of gastrulation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O42248	P	Seeded From UniProt	complete
involved_in	GO:2000114	regulation of establishment of cell polarity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O42248	P	Seeded From UniProt	complete
involved_in	GO:0051302	regulation of cell division	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O42248	P	Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P68040	C	Seeded From UniProt	complete
involved_in	GO:0032880	regulation of protein localization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O42248	P	Seeded From UniProt	complete
involved_in	GO:0030178	negative regulation of Wnt signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O42248	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P68040	C	Seeded From UniProt	complete
involved_in	GO:0072344	rescue of stalled ribosome	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 UniProtKB:P63244	P	Seeded From UniProt	complete
enables	GO:0043022	ribosome binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 PomBase:SPAC6B12.15 UniProtKB:P63244	F	Seeded From UniProt	complete
part_of	GO:0022627	cytosolic small ribosomal subunit	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 SGD:S000004722	C	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 UniProtKB:P63244	F	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 TAIR:locus:2008159 TAIR:locus:2194060 UniProtKB:P63244 UniProtKB:Q8IBA0 dictyBase:DDB_G0275045	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 TAIR:locus:2008159 TAIR:locus:2194060 UniProtKB:P63244	C	Seeded From UniProt	complete
enables	GO:0005080	protein kinase C binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 PomBase:SPAC6B12.15 RGD:69229 UniProtKB:P63244 UniProtKB:Q8IBA0	F	Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000458645 UniProtKB:P63244	P	Seeded From UniProt	complete
involved_in	GO:0061099	negative regulation of protein tyrosine kinase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0030292	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9KL35 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:E9KL35 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
involved_in	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
part_of	GO:1990630	IRE1-RACK1-PP2A complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
involved_in	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0072344	rescue of stalled ribosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0071363	cellular response to growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0071333	cellular response to glucose stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0051901	positive regulation of mitochondrial depolarization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0051898	negative regulation of protein kinase B signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0051726	regulation of cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0050765	negative regulation of phagocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0043065	positive regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
enables	GO:0043022	ribosome binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
involved_in	GO:0042998	positive regulation of Golgi to plasma membrane protein transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
enables	GO:0042169	SH2 domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
enables	GO:0035591	signaling adaptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
involved_in	GO:0033137	negative regulation of peptidyl-serine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0032464	positive regulation of protein homooligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
enables	GO:0030971	receptor tyrosine kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
enables	GO:0030332	cyclin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
involved_in	GO:0030308	negative regulation of cell growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
enables	GO:0030292	protein tyrosine kinase inhibitor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
enables	GO:0019903	protein phosphatase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
enables	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
involved_in	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
enables	GO:0005080	protein kinase C binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	F	Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	P	Seeded From UniProt	complete
part_of	GO:0001891	phagocytic cup	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63244 ensembl:ENSP00000426909	C	Seeded From UniProt	complete
involved_in	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	P	Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	C	Seeded From UniProt	complete
involved_in	GO:0043473	pigmentation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	P	Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	C	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	C	Seeded From UniProt	complete
enables	GO:0008200	ion channel inhibitor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	F	Seeded From UniProt	complete
involved_in	GO:0006412	translation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68040 ensembl:ENSMUSP00000020640	C	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	PMID:2499885^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005840	ribosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0689	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0283	C	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0198	C	Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0197	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Guillemot, F et al. (1989) Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex. Proc. Natl. Acad. Sci. U.S.A. 86 4594-8 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:2499885-2] Guillemot, F et al. (1989) Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex. Proc. Natl. Acad. Sci. U.S.A. 86 4594-8 PubMed GONUTS page

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CHICK:GBLP

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Notes

References

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