CHICK:ANXA2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ANXA2 (synonyms: ANX2)
Protein Name(s)	Annexin A2 Annexin II Annexin-2 Calpactin I heavy chain Calpactin-1 heavy chain Chromobindin-8 Lipocortin II Placental anticoagulant protein IV PAP-IV Protein I p36
External Links
UniProt	P17785
EMBL	X53334
PIR	S10501
RefSeq	NP_990682.1
UniGene	Gga.3641
PDB	1BT6
PDBsum	1BT6
ProteinModelPortal	P17785
SMR	P17785
STRING	9031.ENSGALP00000038695
PaxDb	P17785
PRIDE	P17785
Ensembl	ENSGALT00000005981
GeneID	396297
KEGG	gga:396297
CTD	302
eggNOG	NOG259189
GeneTree	ENSGT00760000118972
HOGENOM	HOG000158803
HOVERGEN	HBG061815
InParanoid	P17785
KO	K17092
OMA	FIQQDTK
OrthoDB	EOG74XS72
PhylomeDB	P17785
TreeFam	TF105452
Reactome	REACT_353705
EvolutionaryTrace	P17785
NextBio	20816347
PRO	PR:P17785
Proteomes	UP000000539
GO	GO:0005604 GO:0016323 GO:0034704 GO:0009986 GO:0005769 GO:0070062 GO:0005615 GO:0019897 GO:0031902 GO:0005811 GO:0005765 GO:0045121 GO:0030496 GO:0035749 GO:0005634 GO:0042383 GO:0043220 GO:0031982 GO:0005262 GO:0005509 GO:0005544 GO:0005546 GO:0019834 GO:0044822 GO:0030546 GO:0001525 GO:0055074 GO:0070588 GO:0030199 GO:0042730 GO:0006900 GO:0001765 GO:0032804 GO:1900121 GO:0002091 GO:0036035 GO:0051099 GO:0031340 GO:0051290
Gene3D	1.10.220.10
InterPro	IPR001464 IPR018502 IPR018252 IPR002389
PANTHER	PTHR10502:SF18
Pfam	PF00191
PRINTS	PR00196 PR00198
SMART	SM00335
PROSITE	PS00223

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0032991	protein-containing complex	PMID:2973411^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0060956	endocardial cell differentiation	PMID:14697359^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0036366	transforming growth factor beta3 activation	PMID:14697359^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032907	transforming growth factor beta3 production	PMID:14697359^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010755	regulation of plasminogen activation	PMID:14697359^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051928	positive regulation of calcium ion transport	PMID:10956650^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0099511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	PMID:10956650^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0032332	positive regulation of chondrocyte differentiation	PMID:10956650^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031982	vesicle	PMID:10956650^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:10956650^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0003417	growth plate cartilage development	PMID:10956650^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0046790	virion binding	PMID:26221766^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(GO:0020002)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:26221766^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:1905599	positive regulation of low-density lipoprotein receptor activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:1905581	positive regulation of low-density lipoprotein particle clearance	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:1903902	positive regulation of viral life cycle	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P19620	P		Seeded From UniProt	complete
enables	GO:0099511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	F		Seeded From UniProt	complete
involved_in	GO:0072659	protein localization to plasma membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 RGD:621170	P		Seeded From UniProt	complete
involved_in	GO:0060956	endocardial cell differentiation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	P		Seeded From UniProt	complete
involved_in	GO:0052405	negative regulation by host of symbiont molecular function	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0052362	catabolism by host of symbiont protein	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0051928	positive regulation of calcium ion transport	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	P		Seeded From UniProt	complete
involved_in	GO:0051290	protein heterotetramerization	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0048146	positive regulation of fibroblast proliferation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 RGD:621170	P		Seeded From UniProt	complete
enables	GO:0046790	virion binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	F		Seeded From UniProt	complete
involved_in	GO:0044794	positive regulation by host of viral process	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P19620	P		Seeded From UniProt	complete
enables	GO:0044730	bone sialoprotein binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 RGD:621170	F		Seeded From UniProt	complete
enables	GO:0044548	S100 protein binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355 UniProtKB:P19620	F		Seeded From UniProt	complete
involved_in	GO:0044147	negative regulation of development of symbiont involved in interaction with host	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0044090	positive regulation of vacuole organization	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	F		Seeded From UniProt	complete
involved_in	GO:0042730	fibrinolysis	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598	P		Seeded From UniProt	complete
involved_in	GO:0036035	osteoclast development	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0032332	positive regulation of chondrocyte differentiation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	P		Seeded From UniProt	complete
part_of	GO:0031982	vesicle	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 RGD:621170 UniProtKB:P04272 UniProtKB:P07355 UniProtKB:P17785 UniProtKB:Q6TEQ7	C		Seeded From UniProt	complete
involved_in	GO:0031340	positive regulation of vesicle fusion	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0031214	biomineral tissue development	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P04272	P		Seeded From UniProt	complete
involved_in	GO:0030199	collagen fibril organization	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598	P		Seeded From UniProt	complete
enables	GO:0019834	phospholipase A2 inhibitor activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	F		Seeded From UniProt	complete
enables	GO:0017137	Rab GTPase binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 RGD:621170	F		Seeded From UniProt	complete
involved_in	GO:0010755	regulation of plasminogen activation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	P		Seeded From UniProt	complete
involved_in	GO:0006900	vesicle budding from membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 RGD:621170 UniProtKB:P07355 UniProtKB:P17785	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 RGD:621170 UniProtKB:P04272 UniProtKB:P07355 UniProtKB:Q6TEQ7	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P04272	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	C		Seeded From UniProt	complete
enables	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 RGD:621170 UniProtKB:P07355	F		Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	F		Seeded From UniProt	complete
enables	GO:0005262	calcium channel activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P04272	F		Seeded From UniProt	complete
involved_in	GO:0003417	growth plate cartilage development	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P17785	P		Seeded From UniProt	complete
enables	GO:0002020	protease binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	F		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 RGD:621170	P		Seeded From UniProt	complete
involved_in	GO:0001921	positive regulation of receptor recycling	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
enables	GO:0001786	phosphatidylserine binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P04272	F		Seeded From UniProt	complete
involved_in	GO:0001765	membrane raft assembly	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88246 PANTHER:PTN000052598 UniProtKB:P07355	P		Seeded From UniProt	complete
involved_in	GO:0043086	negative regulation of catalytic activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004859	P		Seeded From UniProt	complete
involved_in	GO:0043086	negative regulation of catalytic activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0019834	P		Seeded From UniProt	complete
involved_in	GO:0043086	negative regulation of catalytic activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0019834	P		Seeded From UniProt	complete
involved_in	GO:0051480	regulation of cytosolic calcium ion concentration	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0099511	P		Seeded From UniProt	complete
involved_in	GO:0051480	regulation of cytosolic calcium ion concentration	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0099511	P		Seeded From UniProt	complete
involved_in	GO:0051480	regulation of cytosolic calcium ion concentration	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0099511	P		Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005262	P		Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005262	P		Seeded From UniProt	complete
part_of	GO:1990667	PCSK9-AnxA2 complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
involved_in	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:1905599	positive regulation of low-density lipoprotein receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:1905581	positive regulation of low-density lipoprotein particle clearance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
enables	GO:0098772	molecular function regulator	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
involved_in	GO:0052405	negative regulation by host of symbiont molecular function	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:0052362	catabolism by host of symbiont protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:0051290	protein heterotetramerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
enables	GO:0048306	calcium-dependent protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
enables	GO:0044548	S100 protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
involved_in	GO:0044147	negative regulation of development of symbiont involved in interaction with host	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:0044090	positive regulation of vacuole organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
involved_in	GO:0036035	osteoclast development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
part_of	GO:0031902	late endosome membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
involved_in	GO:0031340	positive regulation of vesicle fusion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
enables	GO:0019834	phospholipase A2 inhibitor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
involved_in	GO:0006900	vesicle budding from membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
part_of	GO:0005811	lipid droplet	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	C		Seeded From UniProt	complete
enables	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
enables	GO:0002020	protease binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	F		Seeded From UniProt	complete
involved_in	GO:0001921	positive regulation of receptor recycling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:0001765	membrane raft assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07355 ensembl:ENSP00000346032	P		Seeded From UniProt	complete
involved_in	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
involved_in	GO:1905599	positive regulation of low-density lipoprotein receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
involved_in	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
involved_in	GO:1905581	positive regulation of low-density lipoprotein particle clearance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
involved_in	GO:0051099	positive regulation of binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
part_of	GO:0043220	Schmidt-Lanterman incisure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
involved_in	GO:0042730	fibrinolysis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
part_of	GO:0042383	sarcolemma	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
part_of	GO:0035749	myelin sheath adaxonal region	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
involved_in	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
involved_in	GO:0030199	collagen fibril organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
part_of	GO:0019897	extrinsic component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	C		Seeded From UniProt	complete
involved_in	GO:0001921	positive regulation of receptor recycling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07356 ensembl:ENSMUSP00000034756	P		Seeded From UniProt	complete
enables	GO:0004859	phospholipase inhibitor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002389	F		Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001464 InterPro:IPR002389 InterPro:IPR018252 InterPro:IPR018502 InterPro:IPR037104	F		Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001464 InterPro:IPR002389 InterPro:IPR018252 InterPro:IPR018502 InterPro:IPR037104	F		Seeded From UniProt	complete
enables	GO:0008092	cytoskeletal protein binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002389	F		Seeded From UniProt	complete
enables	GO:0099511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	PMID:10956650^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:10956650^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031982	vesicle	PMID:10956650^[3] PMID:11696438^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0030282	bone mineralization	PMID:10956650^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0055074	calcium ion homeostasis	PMID:11696438^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0034704	calcium channel complex	PMID:11696438^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005262	calcium channel activity	PMID:11696438^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0111	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C		Seeded From UniProt	complete
part_of	GO:0005604	basement membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0084 UniProtKB-SubCell:SL-0025	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Johnsson, N et al. (1988) p36, the major cytoplasmic substrate of src tyrosine protein kinase, binds to its p11 regulatory subunit via a short amino-terminal amphiphatic helix. EMBO J. 7 2435-42 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Krishnan, S et al. (2004) Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart. Dev. Biol. 265 140-54 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 ^3.9 Kirsch, T et al. (2000) The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage. J. Biol. Chem. 275 35577-83 PubMed GONUTS page
↑ ^4.0 ^4.1 Ren, X et al. (2015) Binding chicken Anx2 is beneficial for infection with infectious bursal disease virus. Virus Res. 210 232-40 PubMed GONUTS page
↑ ^5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 ^5.12 ^5.13 ^5.14 ^5.15 ^5.16 ^5.17 ^5.18 ^5.19 ^5.20 ^5.21 ^5.22 ^5.23 ^5.24 ^5.25 ^5.26 ^5.27 ^5.28 ^5.29 ^5.30 ^5.31 ^5.32 ^5.33 ^5.34 ^5.35 ^5.36 ^5.37 ^5.38 ^5.39 ^5.40 ^5.41 ^5.42 ^5.43 ^5.44 ^5.45 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Pfander, D et al. (2001) Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes. Am. J. Pathol. 159 1777-83 PubMed GONUTS page

[PMID:2973411-1] Johnsson, N et al. (1988) p36, the major cytoplasmic substrate of src tyrosine protein kinase, binds to its p11 regulatory subunit via a short amino-terminal amphiphatic helix. EMBO J. 7 2435-42 PubMed GONUTS page

[PMID:14697359-2] 2.0 ^2.1 ^2.2 ^2.3 Krishnan, S et al. (2004) Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart. Dev. Biol. 265 140-54 PubMed GONUTS page

[PMID:10956650-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 ^3.9 Kirsch, T et al. (2000) The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage. J. Biol. Chem. 275 35577-83 PubMed GONUTS page

[PMID:26221766-4] 4.0 ^4.1 Ren, X et al. (2015) Binding chicken Anx2 is beneficial for infection with infectious bursal disease virus. Virus Res. 210 232-40 PubMed GONUTS page

[PMID:21873635-5] 5.00 ^5.01 ^5.02 ^5.03 ^5.04 ^5.05 ^5.06 ^5.07 ^5.08 ^5.09 ^5.10 ^5.11 ^5.12 ^5.13 ^5.14 ^5.15 ^5.16 ^5.17 ^5.18 ^5.19 ^5.20 ^5.21 ^5.22 ^5.23 ^5.24 ^5.25 ^5.26 ^5.27 ^5.28 ^5.29 ^5.30 ^5.31 ^5.32 ^5.33 ^5.34 ^5.35 ^5.36 ^5.37 ^5.38 ^5.39 ^5.40 ^5.41 ^5.42 ^5.43 ^5.44 ^5.45 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11696438-6] 6.0 ^6.1 ^6.2 ^6.3 Pfander, D et al. (2001) Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes. Am. J. Pathol. 159 1777-83 PubMed GONUTS page

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CHICK:ANXA2

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