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CAEEL:O16720
Contents
| Species (Taxon ID) | Caenorhabditis elegans. (6239) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Protein argonaute (ECO:0000256 with RuleBase:RU361178) | |
| External Links | ||
| UniProt | O16720 | |
| EMBL | FO081675 | |
| RefSeq | NP_871992.1 | |
| UniGene | Cel.38785 | |
| ProteinModelPortal | O16720 | |
| SMR | O16720 | |
| IntAct | O16720 | |
| STRING | 6239.T07D3.7a | |
| PaxDb | O16720 | |
| PRIDE | O16720 | |
| EnsemblMetazoa | T07D3.7a | |
| GeneID | 173468 | |
| KEGG | cel:CELE_T07D3.7 | |
| UCSC | T07D3.7a | |
| CTD | 3355106 | |
| WormBase | T07D3.7a | |
| eggNOG | NOG279895 | |
| GeneTree | ENSGT00760000119148 | |
| HOGENOM | HOG000116043 | |
| InParanoid | O16720 | |
| KO | K11593 | |
| OMA | KERTIGR | |
| PhylomeDB | O16720 | |
| Reactome | REACT_182979 REACT_183789 REACT_258001 | |
| NextBio | 879789 | |
| Proteomes | UP000001940 | |
| ExpressionAtlas | O16720 | |
| GO | GO:0005737 GO:0035068 GO:0035198 GO:0009790 GO:0031047 GO:0002119 | |
| Gene3D | 3.30.420.10 | |
| InterPro | IPR014811 IPR003100 IPR003165 IPR012337 | |
| Pfam | PF08699 PF02170 PF02171 | |
| SMART | SM00949 SM00950 | |
| SUPFAM | SSF101690 SSF53098 | |
| PROSITE | PS50821 PS50822 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0070551 |
endoribonuclease activity, cleaving siRNA-paired mRNA |
ECO:0000314 |
F |
Figure 1 |
complete | |||||
|
enables |
GO:0070551 |
endoribonuclease activity, cleaving siRNA-paired mRNA |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070922 |
small RNA loading onto RISC |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035196 |
production of miRNAs involved in gene silencing by miRNA |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003727 |
single-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016892 |
endoribonuclease activity, producing 3'-phosphomonoesters |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035279 |
mRNA cleavage involved in gene silencing by miRNA |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0035198 |
miRNA binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
WB:WBGene00002285 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0035068 |
micro-ribonucleoprotein complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
WB:WBGene00000105 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009792 |
embryo development ending in birth or egg hatching |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
WB:WBGene00000105 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002119 |
nematode larval development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
WB:WBGene00000105 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0070551 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016892 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031047 |
gene silencing by RNA |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Bouasker, S & Simard, MJ (2012) The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans. Nucleic Acids Res. 40 10452-62 PubMed GONUTS page
- ↑ Chatterjee, S & Grosshans, H (2009) Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461 546-9 PubMed GONUTS page
- ↑ Hutvágner, G et al. (2004) Sequence-specific inhibition of small RNA function. PLoS Biol. 2 E98 PubMed GONUTS page
- ↑ 4.0 4.1 Grishok, A et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 23-34 PubMed GONUTS page
- ↑ Tops, BB et al. (2006) The Caenorhabditis elegans Argonautes ALG-1 and ALG-2: almost identical yet different. Cold Spring Harb. Symp. Quant. Biol. 71 189-94 PubMed GONUTS page
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