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Category:GO:0070551 ! endoribonuclease activity, cleaving siRNA-paired mRNA
name: endoribonuclease activity, cleaving siRNA-paired mRNA
namespace: molecular_function
def: "Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters." [GOC:mah, PMID:15105377]
synonym: "argonaute endoribonuclease activity" RELATED [GOC:mah]
is_a: GO:0016891 ! RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
AmiGO
<GOterm>GO:0070551</GOterm>
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