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CAEEL:H2KZD5

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Chromosome-Segregation and RNAi deficient (ECO:0000313 with EMBL:CCD67715.1)
External Links
UniProt H2KZD5
EMBL BX284604
RefSeq NP_001040938.1
UniGene Cel.6224
ProteinModelPortal H2KZD5
IntAct H2KZD5
STRING 6239.F20D12.1a
EPD H2KZD5
PaxDb H2KZD5
PRIDE H2KZD5
EnsemblMetazoa [example_ID F20D12.1a]
GeneID 177591
KEGG cel:CELE_F20D12.1
CTD 177591
WormBase F20D12.1a
eggNOG KOG1041
ENOG410XP07
GeneTree ENSGT00760000119148
InParanoid H2KZD5
OMA NIHECLK
PhylomeDB H2KZD5
Proteomes UP000001940
ExpressionAtlas H2KZD5
GO GO:0000794
GO:0070090
GO:0005634
GO:0043186
GO:0070551
GO:0003676
GO:0000070
GO:0006379
GO:0016246
Gene3D 3.30.420.10
InterPro IPR003100
IPR003165
IPR012337
Pfam PF02171
SMART SM00949
SM00950
SUPFAM SSF101690
SSF53098
PROSITE PS50822

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005634

nucleus

PMID:22863779[1]

ECO:0000314

C

Figure 2

complete
CACAO 7442

involved_in

GO:1903863

P granule assembly

PMID:28182654[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000070

mitotic sister chromatid segregation

PMID:17110334[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016246

RNA interference

PMID:17110334[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0070551

endoribonuclease activity, cleaving siRNA-paired mRNA

PMID:18007599[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0070090

metaphase plate

PMID:19804758[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0043186

P granule

PMID:19804758[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0090625

mRNA cleavage involved in gene silencing by siRNA

PMID:18007599[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22231398[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:19804758[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000794

condensed nuclear chromosome

PMID:19804758[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0070551

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003165
InterPro:IPR036397

F

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Avgousti, DC et al. (2012) CSR-1 RNAi pathway positively regulates histone expression in C. elegans. EMBO J. 31 3821-32 PubMed GONUTS page
  2. Andralojc, KM et al. (2017) ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans. PLoS Genet. 13 e1006611 PubMed GONUTS page
  3. 3.0 3.1 Yigit, E et al. (2006) Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell 127 747-57 PubMed GONUTS page
  4. 4.0 4.1 Aoki, K et al. (2007) In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans. EMBO J. 26 5007-19 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Claycomb, JM et al. (2009) The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 139 123-34 PubMed GONUTS page
  6. Friend, K et al. (2012) A conserved PUF-Ago-eEF1A complex attenuates translation elongation. Nat. Struct. Mol. Biol. 19 176-83 PubMed GONUTS page