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CAEEL:G5EGR6
Contents
| Species (Taxon ID) | Caenorhabditis elegans. (6239) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Protein argonaute (ECO:0000256 with RuleBase:RU361178) | |
| External Links | ||
| UniProt | G5EGR6 | |
| EMBL | Z69661 Z69663 | |
| PIR | T22391 | |
| RefSeq | NP_001257238.1 | |
| UniGene | Cel.5579 | |
| ProteinModelPortal | G5EGR6 | |
| SMR | G5EGR6 | |
| IntAct | G5EGR6 | |
| PRIDE | G5EGR6 | |
| EnsemblMetazoa | F48F7.1a | |
| GeneID | 181504 | |
| KEGG | cel:CELE_F48F7.1 | |
| CTD | 181504 | |
| WormBase | F48F7.1a | |
| GeneTree | ENSGT00760000119148 | |
| KO | K11593 | |
| OrthoDB | EOG7HHWRC | |
| PhylomeDB | G5EGR6 | |
| Reactome | REACT_182979 REACT_183789 REACT_258001 | |
| NextBio | 914220 | |
| Proteomes | UP000001940 | |
| ExpressionAtlas | G5EGR6 | |
| GO | GO:0005737 GO:0000932 GO:0035068 GO:0035198 GO:0009792 GO:0031047 GO:0040035 GO:0002119 GO:0040025 | |
| Gene3D | 3.30.420.10 | |
| InterPro | IPR014811 IPR003100 IPR003165 IPR012337 | |
| Pfam | PF08699 PF02170 PF02171 | |
| SMART | SM00949 SM00950 | |
| SUPFAM | SSF101690 SSF53098 | |
| PROSITE | PS50821 PS50822 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0070551 |
endoribonuclease activity, cleaving siRNA-paired mRNA |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0040035 |
hermaphrodite genitalia development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0040025 |
vulval development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0035198 |
miRNA binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
WB:WBGene00002285 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0035068 |
micro-ribonucleoprotein complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
WB:WBGene00000106 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009792 |
embryo development ending in birth or egg hatching |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
WB:WBGene00000106 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002119 |
nematode larval development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
WB:WBGene00000106 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000932 |
P-body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090502 |
RNA phosphodiester bond hydrolysis, endonucleolytic |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0070551 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0070551 |
endoribonuclease activity, cleaving siRNA-paired mRNA |
ECO:0000314 |
F |
Figure 1 |
complete | |||||
|
involved_in |
GO:0031047 |
gene silencing by RNA |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Bouasker, S & Simard, MJ (2012) The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans. Nucleic Acids Res. 40 10452-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Grishok, A et al. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106 23-34 PubMed GONUTS page
- ↑ Chatterjee, S & Grosshans, H (2009) Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461 546-9 PubMed GONUTS page
- ↑ Hutvágner, G et al. (2004) Sequence-specific inhibition of small RNA function. PLoS Biol. 2 E98 PubMed GONUTS page
- ↑ 5.0 5.1 Ding, L et al. (2005) The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. Mol. Cell 19 437-47 PubMed GONUTS page
