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YEAST:SFP1

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) SFP1
Protein Name(s) Transcription factor SFP1

Split finger protein 1

External Links
UniProt P32432
EMBL M63577
U19729
BK006945
PIR JH0497
RefSeq NP_013507.1
BioGrid 31660
DIP DIP-1379N
IntAct P32432
MINT P32432
STRING 4932.YLR403W
iPTMnet P32432
MaxQB P32432
PaxDb P32432
PRIDE P32432
EnsemblFungi YLR403W_mRNA
GeneID 851119
KEGG sce:YLR403W
EuPathDB FungiDB:YLR403W
SGD S000004395
InParanoid P32432
KO K19487
OMA YEEAHIA
BioCyc YEAST:G3O-32465-MONOMER
PRO PR:P32432
Proteomes UP000002311
GO GO:0005737
GO:0005634
GO:0003677
GO:0046872
GO:0060963
GO:0045944
GO:0008361
InterPro IPR036236
IPR013087
SMART SM00355
SUPFAM SSF57667
PROSITE PS00028
PS50157

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005634

nucleus

PMID:26928762[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:15466158[2]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000004213
SGD:S000006308

P

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:15353587[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:14555489[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:15466158[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:9832520[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:12089449[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0008361

regulation of cell size

PMID:15466158[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0008361

regulation of cell size

PMID:15806610[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

PMID:15466158[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005737

cytoplasm

PMID:15353587[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:15466158[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:15353587[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:9832520[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000551582
SGD:S000004395
UniProtKB:Q86VZ6

C

Seeded From UniProt

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013087

F

Seeded From UniProt

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:26928762[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:15466158[2]

ECO:0000316

genetic interaction evidence used in manual assertion

SGD:S000004213
SGD:S000006308

P

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:15353587[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:14555489[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0060963

positive regulation of ribosomal protein gene transcription by RNA polymerase II

PMID:15466158[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:9832520[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:12089449[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0008361

regulation of cell size

PMID:15466158[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

involved_in

GO:0008361

regulation of cell size

PMID:15806610[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

PMID:15466158[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005737

cytoplasm

PMID:15353587[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:15466158[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:15353587[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:9832520[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

part_of

GO:0005634

nucleus

PMID:21873635[8]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000551582
SGD:S000004395
UniProtKB:Q86VZ6

C

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:21179020[9]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P32864

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:18467557[10]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P32864

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:16429126[11]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P32864

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:11805837[12]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P32864

F

Seeded From UniProt

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013087

F

Seeded From UniProt

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

part_of

GO:0005634

nucleus

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

GO:0003676

nucleic acid binding

PMID:30804227[13]

ECO:0000256

match to sequence model evidence used in automatic assertion

F

Figure 1. Regulation of growth-related genes by Sfp1 (temporary annotation)

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Yofe, I et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat. Methods 13 371-378 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Jorgensen, P et al. (2004) A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes Dev. 18 2491-505 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Marion, RM et al. (2004) Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. Proc. Natl. Acad. Sci. U.S.A. 101 14315-22 PubMed GONUTS page
  4. ↑ 4.0 4.1 Fingerman, I et al. (2003) Sfp1 plays a key role in yeast ribosome biogenesis. Eukaryotic Cell 2 1061-8 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 5.3 Xu, Z & Norris, D (1998) The SFP1 gene product of Saccharomyces cerevisiae regulates G2/M transitions during the mitotic cell cycle and DNA-damage response. Genetics 150 1419-28 PubMed GONUTS page
  6. ↑ 6.0 6.1 Jorgensen, P et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297 395-400 PubMed GONUTS page
  7. ↑ 7.0 7.1 Cipollina, C et al. (2005) SFP1 is involved in cell size modulation in respiro-fermentative growth conditions. Yeast 22 385-99 PubMed GONUTS page
  8. ↑ 8.0 8.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  9. ↑ Lambert, JP et al. (2010) Defining the budding yeast chromatin-associated interactome. Mol. Syst. Biol. 6 448 PubMed GONUTS page
  10. ↑ Tarassov, K et al. (2008) An in vivo map of the yeast protein interactome. Science 320 1465-70 PubMed GONUTS page
  11. ↑ Gavin, AC et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440 631-6 PubMed GONUTS page
  12. ↑ Ho, Y et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415 180-3 PubMed GONUTS page
  13. ↑ Albert, B et al. (2019) Sfp1 regulates transcriptional networks driving cell growth and division through multiple promoter-binding modes. Genes Dev. 33 288-293 PubMed GONUTS page
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