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YEAST:H1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | HHO1 | |
| Protein Name(s) | Histone H1 | |
| External Links | ||
| UniProt | P53551 | |
| EMBL | U43703 AY557756 BK006949 | |
| PIR | S69056 | |
| RefSeq | NP_015198.1 | |
| PDB | 1UHM 1USS 1UST 1YQA | |
| PDBsum | 1UHM 1USS 1UST 1YQA | |
| DisProt | DP00423 | |
| ProteinModelPortal | P53551 | |
| SMR | P53551 | |
| BioGrid | 36054 | |
| DIP | DIP-6587N | |
| IntAct | P53551 | |
| MINT | MINT-700390 | |
| MaxQB | P53551 | |
| PeptideAtlas | P53551 | |
| EnsemblFungi | [example_ID YPL127C] | |
| GeneID | 855976 | |
| KEGG | sce:YPL127C | |
| EuPathDB | FungiDB:YPL127C | |
| SGD | S000006048 | |
| HOGENOM | HOG000066021 | |
| InParanoid | P53551 | |
| KO | K11275 | |
| OMA | VRANNTL | |
| OrthoDB | EOG715QGS | |
| BioCyc | YEAST:G3O-34026-MONOMER | |
| EvolutionaryTrace | P53551 | |
| NextBio | 980801 | |
| PRO | PR:P53551 | |
| Proteomes | UP000002311 | |
| GO | GO:0000790 GO:0000788 GO:0005634 GO:0003677 GO:0030261 GO:0031936 GO:0045910 GO:0006334 GO:0006355 | |
| Gene3D | 1.10.10.10 | |
| InterPro | IPR005818 IPR005819 IPR011991 | |
| Pfam | PF00538 | |
| PRINTS | PR00624 | |
| SMART | SM00526 | |
| PROSITE | PS51504 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045128 |
negative regulation of reciprocal meiotic recombination |
ECO:0000315 |
P |
Figure 5 shows that "Cells lacking histone H1 (hho1Δ) form fewer Holliday junction intermediates" than the WT. |
complete | |||||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000785 |
chromatin |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031490 |
chromatin DNA binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042301 |
phosphate ion binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042301 |
phosphate ion binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032993 |
protein-DNA complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0097100 |
supercoiled DNA binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045910 |
negative regulation of DNA recombination |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
Missing: with/from | |||
|
involved_in |
GO:0045910 |
negative regulation of DNA recombination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031936 |
negative regulation of chromatin silencing |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000001809 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030261 |
chromosome condensation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0043934) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000790 |
nuclear chromatin |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000788 |
nuclear nucleosome |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045910 |
negative regulation of DNA recombination |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000157378 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031936 |
negative regulation of chromatin silencing |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000157378 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0031492 |
nucleosomal DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2176207 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030261 |
chromosome condensation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000157378 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016584 |
nucleosome positioning |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107502 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0038252 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1917319 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003690 |
double-stranded DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1888530 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000794 |
condensed nuclear chromosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000895062 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000790 |
nuclear chromatin |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000895062 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0000786 |
nucleosome |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006334 |
nucleosome assembly |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Li, C et al. (2008) Linker histone H1 represses recombination at the ribosomal DNA locus in the budding yeast Saccharomyces cerevisiae. Mol. Microbiol. 67 906-19 PubMed GONUTS page
- ↑ Kumar, A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev. 16 707-19 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Sanderson, A et al. (2005) Engineering the structural stability and functional properties of the GI domain into the intrinsically unfolded GII domain of the yeast linker histone Hho1p. J. Mol. Biol. 349 608-20 PubMed GONUTS page
- ↑ Ali, T et al. (2004) Two homologous domains of similar structure but different stability in the yeast linker histone, Hho1p. J. Mol. Biol. 338 139-48 PubMed GONUTS page
- ↑ 5.0 5.1 Ono, K et al. (2003) The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy. Nucleic Acids Res. 31 7199-207 PubMed GONUTS page
- ↑ 6.0 6.1 Downs, JA et al. (2003) Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. Mol. Cell 11 1685-92 PubMed GONUTS page
- ↑ Yu, Q et al. (2009) Saccharomyces cerevisiae linker histone Hho1p functionally interacts with core histone H4 and negatively regulates the establishment of transcriptionally silent chromatin. J. Biol. Chem. 284 740-50 PubMed GONUTS page
- ↑ 8.0 8.1 Bryant, JM et al. (2012) The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae. Mol. Cell. Biol. 32 2771-83 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Freidkin, I & Katcoff, DJ (2001) Specific distribution of the Saccharomyces cerevisiae linker histone homolog HHO1p in the chromatin. Nucleic Acids Res. 29 4043-51 PubMed GONUTS page
- ↑ Ushinsky, SC et al. (1997) Histone H1 in Saccharomyces cerevisiae. Yeast 13 151-61 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 11.3 11.4 11.5 11.6 11.7 11.8 11.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
f
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- GO:0045128 ! negative regulation of reciprocal meiotic recombination
- GO:0045910 ! negative regulation of DNA recombination
- GO:0000790 ! nuclear chromatin
- GO:0000788 ! nuclear nucleosome
- GO:0031492 ! nucleosomal DNA binding
- GO:0000786 ! nucleosome
- GO:0006334 ! nucleosome assembly
- GO:0005634 ! nucleus
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