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XENTR:DICER

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Species (Taxon ID) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). (8364)
Gene Name(s) dicer1
Protein Name(s) Endoribonuclease Dicer
External Links
UniProt B3DLA6
EMBL EU338242
BC167373
RefSeq NP_001123390.2
UniGene Str.39540
STRING 8364.ENSXETP00000050382
GeneID 100170154
KEGG xtr:100170154
CTD 23405
Xenbase XB-GENE-491114
eggNOG COG1111
InParanoid B3DLA6
KO K11592
Proteomes UP000008143
GO GO:0005737
GO:0016442
GO:0005524
GO:0004386
GO:0046872
GO:0004525
GO:0003723
GO:0031054
GO:0030422
GO:0030423
Gene3D 1.10.1520.10
3.40.50.300
InterPro IPR011545
IPR005034
IPR014720
IPR014001
IPR001650
IPR027417
IPR003100
IPR000999
Pfam PF00270
PF03368
PF00271
PF02170
PF00636
SMART SM00487
SM00358
SM00490
SM00949
SM00535
SUPFAM SSF101690
SSF52540
SSF69065
PROSITE PS51327
PS50137
PS51192
PS51194
PS50821
PS00517
PS50142

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0035068

micro-ribonucleoprotein complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9UPY3

C

Seeded From UniProt

complete

involved_in

GO:0031054

pre-miRNA processing

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9UPY3

P

Seeded From UniProt

complete

involved_in

GO:0030423

targeting of mRNA for destruction involved in RNA interference

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9UPY3

P

Seeded From UniProt

complete

involved_in

GO:0030422

production of siRNA involved in RNA interference

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9UPY3

P

Seeded From UniProt

complete

part_of

GO:0070578

RISC-loading complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9UPY3

C

Seeded From UniProt

complete

involved_in

GO:0031054

pre-miRNA processing

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034246
FB:FBgn0039016
MGI:MGI:2177178
PANTHER:PTN001029377
UniProtKB:Q9UPY3
WB:WBGene00000939

P

Seeded From UniProt

complete

involved_in

GO:0030422

production of siRNA involved in RNA interference

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034246
FB:FBgn0039016
MGI:MGI:2177178
PANTHER:PTN000383724
PomBase:SPCC188.13c
UniProtKB:Q9LXW7
UniProtKB:Q9UPY3
WB:WBGene00000939

P

Seeded From UniProt

complete

part_of

GO:0016442

RISC complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034246
FB:FBgn0039016
PANTHER:PTN000383724
UniProtKB:Q9UPY3

C

Seeded From UniProt

complete

involved_in

GO:0006309

apoptotic DNA fragmentation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001029377
WB:WBGene00000939

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034246
FB:FBgn0039016
MGI:MGI:2177178
PANTHER:PTN000383724
PomBase:SPCC188.13c
TAIR:locus:2092409
WB:WBGene00000939

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034246
FB:FBgn0039016
PANTHER:PTN000383724
PomBase:SPCC188.13c
TAIR:locus:2092409
UniProtKB:P84634
UniProtKB:Q9LXW7
UniProtKB:Q9SP32
WB:WBGene00000939

C

Seeded From UniProt

complete

enables

GO:0004530

deoxyribonuclease I activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001029377
WB:WBGene00000939

F

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034246
MGI:MGI:2177178
PANTHER:PTN000383724
TAIR:locus:2092409
UniProtKB:Q9UPY3
WB:WBGene00000939

F

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016891

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011545

F

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000999
InterPro:IPR036389

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011545

F

Seeded From UniProt

complete

involved_in

GO:0006396

RNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000999
InterPro:IPR036389

P

Seeded From UniProt

complete

enables

GO:0016891

endoribonuclease activity, producing 5'-phosphomonoesters

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005034

F

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.26.3

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0004386

helicase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0347

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0031047

gene silencing by RNA

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0943

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page