name: RISC complex
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def: "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation." [PMID:10749213, PMID:15145345]
synonym: "micro-ribonucleoprotein complex" RELATED 
synonym: "miRNP complex" RELATED 
synonym: "RNA-induced silencing complex" EXACT 
is_a: GO:0031332 ! RNAi effector complex
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Pages in category "GO:0016442 ! RISC complex"
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