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User:Xxhaileejxx

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHHV11:ICP02012-10-02 19:28:20 CDTGO:0039548 suppression by virus of host IRF3 activity (P)PMID:2861674ECO:0000314 direct assay evidence used in manual assertion

Figure 1 shows ICP0 inhibits the sustained activation of IRF3 during the later stages of an HSV-1 infection.

challenge
requireschangesHHV11:ICP02012-10-02 19:55:43 CDTGO:0019046 release from viral latency (P)PMID:19264778ECO:0000315 mutant phenotype evidence used in manual assertion

Table 1 shows plaque formation (indicating cell lysis) before and after induction on ICP0 production. Table 10 also shows a summary of the data.

challenge
acceptableEBOZM:VP352012-10-02 20:47:52 CDTGO:0039613 suppression by virus of host protein phosphorylation (P)PMID:12829834ECO:0000314 direct assay evidence used in manual assertion

Figure 4 shows VP35 blocks dimerization and phosphorylation of IRF-3 in response to SeV infection.

challenge

acceptable:1
unacceptable:1
requires_changes:1
flagged:0

Annotations challenged by Xxhaileejxx

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Xxhaileejxx