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User:Powellme

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Phage Hunters Spring 2016

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableLAMBD:PP2016-04-27 09:07:35 CDTGO:0004721 phosphoprotein phosphatase activity (F)PMID:11112522ECO:0000314 direct assay evidence used in manual assertion

Figure 3 lambda active site with bound sulfate(its a phosphate mimic is consistent with the active site components of phosphatase) and solvent molecules

challenge
unacceptableCLOTH:A3DJ382016-04-27 09:13:57 CDTPMID:23595150ECO:0000255 match to sequence model evidence used in manual assertion

Figure 2A tertiary structures as well as overlay shows conservation of structure to lambda phosphatase (with a citrase that mimics phosphate).

challenge
unacceptableCLOTH:A3DJ382016-04-27 09:42:27 CDTGO:0004721 phosphoprotein phosphatase activity (F)PMID:23595150ECO:0000247 sequence alignment evidence used in manual assertion

figure 2D shows aligned structures of the Cth and lambda phosphatase

challenge
unacceptableBPT4:TERL2016-05-02 09:19:00 CDTGO:0043493 viral terminase complex (C)ECO:0000255 match to sequence model evidence used in manual assertion

Terminate acts as a an ATP driven molecular motor for viral DNA translocation

challenge
unacceptableBPT4:UVSW2016-05-02 10:16:10 CDTGO:0016787 hydrolase activity (F)PMID:17878153ECO:0000314 direct assay evidence used in manual assertion

Domains 2a and B shown in figure 3 once combined create architecture this is typical of monomeric helicase .

challenge
unacceptableBPT4:UVSW2016-05-02 10:29:07 CDTGO:0016787 hydrolase activity (F)PMID:17878153ECO:0000314 direct assay evidence used in manual assertion

figure 2 shows both primary and secondary structure assignment of entire molecule. A1, A2, B1,B2 reflects domain locations that are consistent with monomeric helicases

challenge

acceptable:0
unacceptable:6
requires_changes:0
flagged:0

Annotations challenged by Powellme

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableCarsonrm,
Team ContaminatorZ
9CAUD:A0A024B1E1GO:0098027 - virus tail, sheath (C)PMID:25517898ECO:0000314 direct assay evidence used in manual assertionchallengeC: 6
unacceptableGilliabb,
Team ContaminatorZ
9CAUD:A0A024AZP1GO:0098015 - virus tail (C)PMID:25100842ECO:0000314 direct assay evidence used in manual assertionchallengeC: 5
unacceptableWarrierrk,
Team Snorlax
HHV8P:ORF73GO:0046798 - viral portal complex (C)PMID:10400794ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4

0 annotations fixed by Powellme

What do the icons mean in the status column?

assessment icons.jpg