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HHV8P:ORF73
Contents
| Species (Taxon ID) | Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi'ssarcoma-associated herpesvirus). (868565) | |
| Gene Name(s) | ORF73 | |
| Protein Name(s) | Protein ORF73 | |
| External Links | ||
| UniProt | Q9QR71 | |
| EMBL | AF148805 | |
| RefSeq | YP_001129431.1 | |
| PDB | 4UZB 4UZC | |
| PDBsum | 4UZB 4UZC | |
| ProteinModelPortal | Q9QR71 | |
| BioGrid | 1777030 | |
| DIP | DIP-61278N | |
| BindingDB | Q9QR71 | |
| GeneID | 4961527 | |
| KEGG | vg:4961527 | |
| Proteomes | UP000000942 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0046798 |
viral portal complex |
ECO:0000314 |
C |
Matched 100% with KSHV LANA (ORF73) (C-terminal domain, octameric ring: cubic crystal form) with an E-value of 5.4E-60. Figure 2 in the PubMed article shows a northern blot analysis done on two KSHV cell lines. Cellular RNA was probed by a 4.3-kb genomic probe which came from GK18 displayed in Figure 1 of the article. The negative control was taken from the total RNA isolated from the RAJI cell line. There was an equal intensity produced from the class I transcript which ended up serving as the loading control. |
complete | |||||
|
involved_in |
GO:0039644 |
suppression by virus of host NF-kappaB transcription factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039644 |
suppression by virus of host NF-kappaB transcription factor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Li, X et al. (2011) Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen reduces interleukin-8 expression in endothelial cells and impairs neutrophil chemotaxis by degrading nuclear p65. J. Virol. 85 8606-15 PubMed GONUTS page
- ↑ Glenn, M et al. (1999) Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus. J. Virol. 73 6953-63 PubMed GONUTS page
