User:Liza.M.Stremick

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	STREQ:TACY	2016-02-19 11:34:00 CST	GO:0060370 susceptibility to T cell mediated cytotoxicity (P)	PMID:26601609	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 Analyzed various strains cytotoxic effects on keratinocytes.	challenge
unacceptable	STRPY:Q5R2E0	2016-03-07 20:12:02 CST	GO:0008219 cell death (P)	PMID:26838722	ECO:0000315 mutant phenotype evidence used in manual assertion	NADase acts synergistically with SLO to cause cell death in all essentially all of the cells they infect. Mutant forms of the protein only caused cell death in less then 10% of the infected cells.	challenge
unacceptable	STRP3:TACY	2016-03-07 20:17:29 CST	GO:0008219 cell death (P)	PMID:26838722	ECO:0000315 mutant phenotype evidence used in manual assertion	Streptolysin o acts synergistically with NADase+ SPN to destroy cell membranes in infected cells and cause necrosis. In cells infected with mutant types of these proteins less then 10% of the cell membranes were destroyed.	challenge
unacceptable	STRP1:CAS9	2016-03-07 20:45:05 CST	GO:0050765 negative regulation of phagocytosis (P)	PMID:26945067	ECO:0000315 mutant phenotype evidence used in manual assertion	Streptococcus pyogenes uses Factor H to degrade C3B which is responsible for opsinization. This results in evading phagocytosis.	challenge

acceptable:0
unacceptable:4
requires_changes:0
flagged:0

Annotations challenged by Liza.M.Stremick

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Liza.M.Stremick

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