GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:2000932 | positive regulation of cellobiose metabolic process | PMID:28118504 | ECO: 0001147 IMP: Inferred from Mutant Phenotype | Biological Process | In Figure 2, wild type C. japonicus and cel3b, cel3Acel3B, and 4BG mutants were grown on cellobiose and glucose (control). The four strains showed no significant changes in glucose consumption during growth (Fig. 2A & 2B). However, the cel3b mutant showed a decreased rate of cellobiose consumption (Fig. 2C & 2D). This shows that cel3b has a role in efficient cellobiose utilization in C. japonicus. | complete | ||
| This annotation made on page: CELJU:B3PDN7 By: RSpruill (group Team Red B 2019) on 2019-04-10 10:55:50 CDT. | ||||||||
You must be logged in to challenge this annotation.
| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Challenge | ASimpson, Team Purple B 2019 | 2019-04-16 23:37:13 CDT | I would consider changing the GO annotation from "positive" to "negative" regulation. There are no other annotations on QuickGo for these specific annotations, but when compared with other positive and negative regulation examples, it seems like your article matches better to negative regulation. The mutation results in lower rates of consumption of the cellobiose, and so the mutation results in a negative regulation of this process. | 1 | ||||||||||||||||||||||
| Challenge | KAtanasoff, Team Blue A 2019 | 2019-04-15 10:33:23 CDT | Your notes should more specifically cite the panels that use your ECO term of anion-exchange chromatography evidence (i.e. figures 2B and 2D for glucose and cellobiose consumption respectively); as it stands, it's a bit confusing whether you're referring to the growth figures measuring OD600 or the figures measuring levels of glucose/cellobiose. | 2 | ||||||||||||||||||||||
| Public Assessment | Ivanerill | 2019-04-22 09:29:27 CDT | No notes given. | Acceptable ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original | ||||||||||||||||||||||
| Public Assessment | DanielRenfro | 2019-04-21 17:22:32 CDT | This annotation has been flagged because it has been edited since last assessment
| Flagged | ||||||||||||||||||||||
| Public Assessment | Ivanerill | 2019-04-21 15:51:00 CDT | I still do not see a justification for "regulation" of cellobiose metabolic process | Requires Changes ✗ Go term | ||||||||||||||||||||||
| Public Assessment | Ivanerill | 2019-04-20 04:49:34 CDT | Again: Why positive regulation? Describe in your notes what in the figure supports that claim; otherwise just switch to cellobiose metabolic process. | Requires Changes ✔ Protein ✔ Publication ✔ Qualifier ✗ Go term ✔ Evidence ✔ With/From ✗ Notes ✔ Unique/Original | ||||||||||||||||||||||
| Public Assessment | DanielRenfro | 2019-04-19 11:38:45 CDT | This annotation has been flagged because it has been edited since last assessment
| Flagged | ||||||||||||||||||||||
| Public Assessment | Ivanerill | 2019-04-18 09:29:45 CDT | Your ECO term id seems to contain a space (ECO: 0001147). Please remove it. Why positive regulation? Describe what in the figure supports that claim; otherwise just switch to cellobiose metabolic process . | Requires Changes ✔ Protein ✔ Publication ✔ Qualifier ✗ Go term ✔ Evidence ✔ With/From ✗ Notes ✔ Unique/Original |
