GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| Contributes to | GO:0033041 | sweet taste receptor activity | PMID:11509186 | ECO:0001565 IDA: Inferred from Direct Assay | Molecular Function | Dose responses (normalized to responses observed from the highest concentration per compound) were observed for the sweet compounds GA-2, saccharin, acesulfame-K, and sucrose in the receptor combination T1R2+3 (Fig 6b), matching the biological thresholds observed in vivo (Fig 6a). Dose responses were not observed for bitter or umami compounds (Fig 6b) | complete | |
| This annotation made on page: MOUSE:TS1R2 By: LWachhaus (group Team Red B 2019) on 2019-03-10 15:06:43 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Public Assessment | Ivanerill | 2019-04-21 16:52:08 CDT | No notes given. | Unacceptable |
| Public Assessment | Ivanerill | 2019-03-13 09:22:21 CDT | Would need to describe what the dose response curves are precisely, and argue that they prove molecular function (as opposed to biological process). The ECO term should obviously be revised towards specificity. Please use the cross-linked evidence terms from ECO (i.e. those that end in "used in manual assertion" or "used in automatic assertion") Most instances of evidence you will come across will be of type "used in manual assertion". Terms with "used in automatic assertion" imply that the authors did not make a conscious effort to analyze the results of an experiment, letting an algorithm make the call. For instance, if somebody were to use BLAST to determine that a bunch of proteins are homologous (and hence have the same function as the query) and they do not assess the BLAST results in any way (just accept whatever BLAST returns as significant given a preestablished threshold) that could be thought of as an "automatic assertion". Eukaryotic annotation is NOT allowed from now on in Phage Hunters CACAO. | Requires Changes ✔ Protein ✔ Publication ✗ Go term ✗ Evidence ✗ Notes |
| Private Assessment | Ivanerill | 2019-03-11 15:51:46 CDT | You need to be an instructor to view these notes. | Requires Changes ✔ Protein ✔ Publication ✗ Go term ✗ Evidence ✗ Notes |
