RAT:PARK7

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Park7 (synonyms: Cap1)
Protein Name(s)	Protein DJ-1 Contraception-associated protein 1 Protein CAP1 Fertility protein SP22 Parkinson disease protein 7 homolog
External Links
UniProt	O88767
EMBL	AJ007291 AF157511 AF157512
PIR	JE0344
RefSeq	NP_001264179.1 NP_001264180.1 NP_001264181.1 NP_001264182.1 NP_476484.1
UniGene	Rn.30105
ProteinModelPortal	O88767
SMR	O88767
BioGrid	250731
IntAct	O88767
MINT	MINT-4577505
STRING	10116.ENSRNOP00000052374
MEROPS	C56.002
PhosphoSite	O88767
World-2DPAGE	0004:O88767
PaxDb	O88767
PRIDE	O88767
Ensembl	ENSRNOT00000024711
GeneID	117287
KEGG	rno:117287
UCSC	RGD:621808
CTD	11315
RGD	621808
eggNOG	COG0693
GeneTree	ENSGT00390000001231
HOGENOM	HOG000063194
HOVERGEN	HBG053511
InParanoid	O88767
KO	K05687
OMA	MAGDHYK
OrthoDB	EOG7CVPZX
NextBio	620247
PRO	PR:O88767
Proteomes	UP000002494
Genevestigator	O88767
GO	GO:0030424 GO:0005737 GO:0005829 GO:0070062 GO:0045121 GO:0005739 GO:0005634 GO:0005886 GO:0016605 GO:0050681 GO:1903135 GO:1903136 GO:0019955 GO:1990422 GO:0019172 GO:0036478 GO:0003729 GO:0008233 GO:0042803 GO:0005102 GO:0070491 GO:0097110 GO:0044388 GO:0044390 GO:0016532 GO:0003713 GO:0008134 GO:0036470 GO:1990381 GO:0006914 GO:0036471 GO:0070301 GO:0034599 GO:0009566 GO:0046295 GO:1903190 GO:0042743 GO:0006954 GO:0019249 GO:0019243 GO:0007005 GO:0060548 GO:2001268 GO:2001237 GO:0043524 GO:1903377 GO:1901984 GO:0032091 GO:0046826 GO:1903094 GO:0006469 GO:0001933 GO:0033234 GO:0031397 GO:1903122 GO:2000157 GO:2000825 GO:1903181 GO:0032757 GO:1903197 GO:1903200 GO:1902958 GO:2000277 GO:0090073 GO:1900182 GO:1903168 GO:1901671 GO:0045944 GO:1903178 GO:0050821 GO:0060765 GO:0050727 GO:0051881 GO:0043523 GO:0042493 GO:0006979 GO:0007338
Gene3D	3.40.50.880
InterPro	IPR029062 IPR006287 IPR002818
Pfam	PF01965
SUPFAM	SSF52317
TIGRFAMs	TIGR01383

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0003729	mRNA binding	GO_REF:0000024	ECO:0000250		UniProtKB:Q99497	F		complete
involved_in	GO:0033864	positive regulation of NAD(P)H oxidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0106046	guanine deglycation, glyoxal removal	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0106045	guanine deglycation, methylglyoxal removal	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0106044	guanine deglycation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0042593	glucose homeostasis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0030073	insulin secretion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
NOT\|involved_in	GO:0036530	protein deglycation, methylglyoxal removal	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
NOT\|involved_in	GO:0009438	methylglyoxal metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
NOT\|involved_in	GO:0006517	protein deglycosylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0006517	protein deglycosylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
enables	GO:0045340	mercury ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0005507	copper ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
involved_in	GO:0050787	detoxification of mercury ion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0010273	detoxification of copper ion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	C	Seeded From UniProt	complete
part_of	GO:0016605	PML body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	C	Seeded From UniProt	complete
colocalizes_with	GO:0005747	mitochondrial respiratory chain complex I	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	C	Seeded From UniProt	complete
enables	GO:1903136	cuprous ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:1903135	cupric ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0097110	scaffold protein binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0070491	repressing transcription factor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0050681	androgen receptor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0044390	ubiquitin-like protein conjugating enzyme binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0044388	small protein activating enzyme binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0036478	L-dopa decarboxylase activator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0036470	tyrosine 3-monooxygenase activator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0019955	cytokine binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0016532	superoxide dismutase copper chaperone activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
enables	GO:0003713	transcription coactivator activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
involved_in	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:2000825	positive regulation of androgen receptor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903200	positive regulation of L-dopa decarboxylase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903197	positive regulation of L-dopa biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903181	positive regulation of dopamine biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903168	positive regulation of pyrroline-5-carboxylate reductase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903122	negative regulation of TRAIL-activated apoptotic signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1903094	negative regulation of protein K48-linked deubiquitination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0060765	regulation of androgen receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0051881	regulation of mitochondrial membrane potential	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0046295	glycolate biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0043524	negative regulation of neuron apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0042743	hydrogen peroxide metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0036471	cellular response to glyoxal	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0034599	cellular response to oxidative stress	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0032757	positive regulation of interleukin-8 production	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:2000157	negative regulation of ubiquitin-specific protease activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1901984	negative regulation of protein acetylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1901671	positive regulation of superoxide dismutase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:1900182	positive regulation of protein localization to nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0090073	positive regulation of protein homodimerization activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0046826	negative regulation of protein export from nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0033234	negative regulation of protein sumoylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0031397	negative regulation of protein ubiquitination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0006469	negative regulation of protein kinase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0001933	negative regulation of protein phosphorylation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0070301	cellular response to hydrogen peroxide	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0070301	cellular response to hydrogen peroxide	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0050727	regulation of inflammatory response	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0043523	regulation of neuron apoptotic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
involved_in	GO:0034599	cellular response to oxidative stress	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
involved_in	GO:0032091	negative regulation of protein binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	P	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
involved_in	GO:0007005	mitochondrion organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99LX0	P	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	C	Seeded From UniProt	complete
enables	GO:0003729	mRNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q99497	F	Seeded From UniProt	complete
involved_in	GO:1905516	positive regulation of fertilization	PMID:11780923^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:1904782	negative regulation of NMDA glutamate receptor activity	PMID:20698836^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:1901215	negative regulation of neuron death	PMID:20698836^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0071222	cellular response to lipopolysaccharide	PMID:23847046^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0061827	sperm head	PMID:11780923^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0060135	maternal process involved in female pregnancy	PMID:17609507^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:23847046^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	PMID:17038803^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:15673657^[6]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0007568	aging	PMID:25788877^[7]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	PMID:11780923^[1]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0006979	response to oxidative stress	PMID:16227205^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:17038803^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16246899^[9]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0106046	guanine deglycation, glyoxal removal	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000111103 UniProtKB:Q99497	P	Seeded From UniProt	complete
involved_in	GO:0036529	protein deglycation, glyoxal removal	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000111103 UniProtKB:Q99497	P	Seeded From UniProt	complete
enables	GO:0036524	protein deglycase activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13272 PANTHER:PTN000111103 UniProtKB:Q99497	F	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13272 MGI:MGI:2135637 PANTHER:PTN000111103 PomBase:SPAC22E12.03c RGD:621808 TAIR:locus:2086295 UniProtKB:C6KTB1 UniProtKB:Q99497	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2135637 PANTHER:PTN000111108 PomBase:SPAC22E12.03c RGD:621808 TAIR:locus:2086295 UniProtKB:Q99497 WB:WBGene00015184	C	Seeded From UniProt	complete
involved_in	GO:0009566	fertilization	PMID:14662519^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496 UniProtKB-SubCell:SL-0173	C	Seeded From UniProt	complete
involved_in	GO:0007338	single fertilization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0278	P	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0072	P	Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0395	P	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0370	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Klinefelter, GR et al. () Localization of the sperm protein SP22 and inhibition of fertility in vivo and in vitro. J. Androl. 23 48-63 PubMed GONUTS page
↑ ^2.0 ^2.1 Chang, N et al. (2010) Differential regulation of NMDA receptor function by DJ-1 and PINK1. Aging Cell 9 837-50 PubMed GONUTS page
↑ ^3.0 ^3.1 Kim, KS et al. (2013) DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. Hum. Mol. Genet. 22 4805-17 PubMed GONUTS page
↑ Benoit, AM et al. (2007) Expression of sperm protein 22 (SP22) in the rat ovary during different reproductive states. Exp. Biol. Med. (Maywood) 232 910-20 PubMed GONUTS page
↑ ^5.0 ^5.1 Yanagida, T et al. (2006) Distribution of DJ-1, Parkinson's disease-related protein PARK7, and its alteration in 6-hydroxydopamine-treated hemiparkinsonian rat brain. J. Pharmacol. Sci. 102 243-7 PubMed GONUTS page
↑ Willis, D et al. (2005) Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons. J. Neurosci. 25 778-91 PubMed GONUTS page
↑ Böhm, MR et al. (2015) Life-time expression of the proteins peroxiredoxin, beta-synuclein, PARK7/DJ-1, and stathmin in the primary visual and primary somatosensory cortices in rats. Front Neuroanat 9 16 PubMed GONUTS page
↑ Zhou, W & Freed, CR (2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity. J. Biol. Chem. 280 43150-8 PubMed GONUTS page
↑ Benoit, AM et al. (2005) Localization of fertility factor SP22 to specific cell types within the anterior pituitary gland. Exp. Biol. Med. (Maywood) 230 721-30 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 ^10.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Bandopadhyay, R et al. (2004) The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain 127 420-30 PubMed GONUTS page

[PMID:11780923-1] 1.0 ^1.1 ^1.2 Klinefelter, GR et al. () Localization of the sperm protein SP22 and inhibition of fertility in vivo and in vitro. J. Androl. 23 48-63 PubMed GONUTS page

[PMID:20698836-2] 2.0 ^2.1 Chang, N et al. (2010) Differential regulation of NMDA receptor function by DJ-1 and PINK1. Aging Cell 9 837-50 PubMed GONUTS page

[PMID:23847046-3] 3.0 ^3.1 Kim, KS et al. (2013) DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes. Hum. Mol. Genet. 22 4805-17 PubMed GONUTS page

[PMID:17609507-4] Benoit, AM et al. (2007) Expression of sperm protein 22 (SP22) in the rat ovary during different reproductive states. Exp. Biol. Med. (Maywood) 232 910-20 PubMed GONUTS page

[PMID:17038803-5] 5.0 ^5.1 Yanagida, T et al. (2006) Distribution of DJ-1, Parkinson's disease-related protein PARK7, and its alteration in 6-hydroxydopamine-treated hemiparkinsonian rat brain. J. Pharmacol. Sci. 102 243-7 PubMed GONUTS page

[PMID:15673657-6] Willis, D et al. (2005) Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons. J. Neurosci. 25 778-91 PubMed GONUTS page

[PMID:25788877-7] Böhm, MR et al. (2015) Life-time expression of the proteins peroxiredoxin, beta-synuclein, PARK7/DJ-1, and stathmin in the primary visual and primary somatosensory cortices in rats. Front Neuroanat 9 16 PubMed GONUTS page

[PMID:16227205-8] Zhou, W & Freed, CR (2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity. J. Biol. Chem. 280 43150-8 PubMed GONUTS page

[PMID:16246899-9] Benoit, AM et al. (2005) Localization of fertility factor SP22 to specific cell types within the anterior pituitary gland. Exp. Biol. Med. (Maywood) 230 721-30 PubMed GONUTS page

[PMID:21873635-10] 10.0 ^10.1 ^10.2 ^10.3 ^10.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:14662519-11] Bandopadhyay, R et al. (2004) The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain 127 420-30 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

RAT:PARK7

Contents

Annotations

Notes

References

a

c

d

e

f

g

h

i

l

m

n

o

p

r

s

t

u

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools