RAT:GBRAP

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Gabarap
Protein Name(s)	Gamma-aminobutyric acid receptor-associated protein GABA(A) receptor-associated protein
External Links
UniProt	P60517
EMBL	AF161588 BC058441
RefSeq	NP_742033.1
UniGene	Rn.8411
PDB	1KJT
PDBsum	1KJT
ProteinModelPortal	P60517
SMR	P60517
BioGrid	248705
IntAct	P60517
STRING	10116.ENSRNOP00000023724
PRIDE	P60517
Ensembl	ENSRNOT00000023724
GeneID	58974
KEGG	rno:58974
UCSC	RGD:61911
CTD	11337
RGD	61911
eggNOG	NOG263746
GeneTree	ENSGT00390000012937
HOGENOM	HOG000232034
HOVERGEN	HBG051706
InParanoid	P60517
KO	K08341
OMA	VYGSSQR
OrthoDB	EOG70KGRK
PhylomeDB	P60517
TreeFam	TF314556
EvolutionaryTrace	P60517
NextBio	611644
PRO	PR:P60517
Proteomes	UP000002494
Genevestigator	P60517
GO	GO:0015629 GO:0005776 GO:0000421 GO:0005930 GO:0044297 GO:0031410 GO:0000139 GO:0005764 GO:0005874 GO:0005875 GO:0048471 GO:0005886 GO:0005790 GO:0050811 GO:0006914 GO:0008625 GO:0000226 GO:0015031
InterPro	IPR004241 IPR029071
PANTHER	PTHR10969
Pfam	PF02991
SUPFAM	SSF54236

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O95166	P	Seeded From UniProt	complete
part_of	GO:0005930	axoneme	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9DCD6	C	Seeded From UniProt	complete
part_of	GO:0005776	autophagosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O95166	C	Seeded From UniProt	complete
enables	GO:0050811	GABA receptor binding	PMID:15601949^[1]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:62259	F	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	PMID:15601949^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0044297	cell body	PMID:15601949^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	PMID:18160640^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	PMID:15601949^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0050811	GABA receptor binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000861087 RGD:61911 UniProtKB:O95166	F	Seeded From UniProt	complete
involved_in	GO:0006995	cellular response to nitrogen starvation	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000103522 dictyBase:DDB_G0286191	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000103525 RGD:735183 UniProtKB:P60519 UniProtKB:Q9H492	C	Seeded From UniProt	complete
involved_in	GO:0000422	autophagy of mitochondrion	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000103525 UniProtKB:Q9GZQ8 UniProtKB:Q9H492	P	Seeded From UniProt	complete
part_of	GO:0000421	autophagosome membrane	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1915661 PANTHER:PTN000103525 RGD:621315 RGD:735183 UniProtKB:O95166 UniProtKB:P60520 WB:WBGene00002980 WB:WBGene00002981	C	Seeded From UniProt	complete
involved_in	GO:0000045	autophagosome assembly	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000103525 RGD:735183 UniProtKB:Q9H492	P	Seeded From UniProt	complete
enables	GO:0050811	GABA receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95166 ensembl:ENSP00000306866	F	Seeded From UniProt	complete
enables	GO:0048487	beta-tubulin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95166 ensembl:ENSP00000306866	F	Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95166 ensembl:ENSP00000306866	F	Seeded From UniProt	complete
involved_in	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95166 ensembl:ENSP00000306866	P	Seeded From UniProt	complete
part_of	GO:0005776	autophagosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95166 ensembl:ENSP00000306866	C	Seeded From UniProt	complete
part_of	GO:0000421	autophagosome membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95166 ensembl:ENSP00000306866	C	Seeded From UniProt	complete
part_of	GO:0097225	sperm midpiece	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
part_of	GO:0015629	actin cytoskeleton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	F	Seeded From UniProt	complete
part_of	GO:0005930	axoneme	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
part_of	GO:0005875	microtubule associated complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
part_of	GO:0005790	smooth endoplasmic reticulum	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	C	Seeded From UniProt	complete
involved_in	GO:0000226	microtubule cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9DCD6 ensembl:ENSMUSP00000018711	P	Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P	Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0493	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333	C	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0072	P	Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206 UniProtKB-SubCell:SL-0090	C	Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0053	P	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C	Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0147	C	Seeded From UniProt	complete
part_of	GO:0000139	Golgi membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0134	C	Seeded From UniProt	complete
part_of	GO:0005776	autophagosome	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0023	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Leil, TA et al. (2004) GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons. J. Neurosci. 24 11429-38 PubMed GONUTS page
↑ Marsden, KC et al. (2007) NMDA receptor activation potentiates inhibitory transmission through GABA receptor-associated protein-dependent exocytosis of GABA(A) receptors. J. Neurosci. 27 14326-37 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15601949-1] 1.0 ^1.1 ^1.2 ^1.3 Leil, TA et al. (2004) GABAA receptor-associated protein traffics GABAA receptors to the plasma membrane in neurons. J. Neurosci. 24 11429-38 PubMed GONUTS page

[PMID:18160640-2] Marsden, KC et al. (2007) NMDA receptor activation potentiates inhibitory transmission through GABA receptor-associated protein-dependent exocytosis of GABA(A) receptors. J. Neurosci. 27 14326-37 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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RAT:GBRAP

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