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RAT:F1M7B8
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Protein Ube3a (ECO:0000313 with Ensembl:ENSRNOP00000021366) | |
| External Links | ||
| UniProt | F1M7B8 | |
| EMBL | AABR07003599 AABR07003600 | |
| RefSeq | NP_001178766.1 XP_006229372.1 | |
| UniGene | Rn.162420 | |
| STRING | 10116.ENSRNOP00000021366 | |
| PaxDb | F1M7B8 | |
| PRIDE | F1M7B8 | |
| Ensembl | ENSRNOT00000021366 | |
| GeneID | 361585 | |
| KEGG | rno:361585 | |
| CTD | 7337 | |
| RGD | 1306361 | |
| eggNOG | KOG0941 COG5021 | |
| GeneTree | ENSGT00830000128260 | |
| InParanoid | F1M7B8 | |
| KO | K10587 | |
| OMA | VEEDMMI | |
| OrthoDB | EOG7NKKJP | |
| TreeFam | TF315189 | |
| Proteomes | UP000002494 | |
| ExpressionAtlas | F1M7B8 | |
| GO | GO:0005737 GO:0005829 GO:0005634 GO:0016874 GO:0003713 GO:0061630 GO:0004842 GO:0030521 GO:0001541 GO:0014068 GO:0031398 GO:0045944 GO:0060736 GO:0051865 GO:0070936 GO:0042787 GO:0042752 GO:2000058 GO:0035037 | |
| InterPro | IPR032353 IPR000569 IPR017134 | |
| Pfam | PF16558 PF00632 | |
| PIRSF | PIRSF037201 | |
| SMART | SM00119 | |
| SUPFAM | SSF56204 | |
| PROSITE | PS50237 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:1990416 |
cellular response to brain-derived neurotrophic factor stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:1905528 |
positive regulation of Golgi lumen acidification |
ECO:0000315 |
P |
A fluorometric assay was used to determine Golgi lumen pH in Ube3a-knockdown rat cells as compared to control. Figure 5B shows the calibration curve used to convert YFP:CFP intensity ratio to pH; Figure D shows the fluorescence intensity and figure 5E shows the pH as calculated using the calibration curve. |
complete | |||||
|
involved_in |
GO:0061002 |
negative regulation of dendritic spine morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042542 |
response to hydrogen peroxide |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042220 |
response to cocaine |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005575 |
cellular_component |
ECO:0000307 |
no biological data found used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043161 |
proteasome-mediated ubiquitin-dependent protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0061469 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0061469 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000209 |
protein polyubiquitination |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0061469 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0061630 |
ubiquitin protein ligase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060736 |
prostate gland growth |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035037 |
sperm entry |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030521 |
androgen receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016567 |
protein ubiquitination |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003713 |
transcription coactivator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001541 |
ovarian follicle development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08759 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0061630 |
ubiquitin protein ligase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Valluy, J et al. (2015) A coding-independent function of an alternative Ube3a transcript during neuronal development. Nat. Neurosci. 18 666-73 PubMed GONUTS page
- ↑ Condon, KH et al. (2013) The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation. J. Neurosci. 33 3799-814 PubMed GONUTS page
- ↑ LaVoie, MJ et al. (2007) The effects of oxidative stress on parkin and other E3 ligases. J. Neurochem. 103 2354-68 PubMed GONUTS page
- ↑ Caffino, L et al. (2014) Long-term abstinence from developmental cocaine exposure alters Arc/Arg3.1 modulation in the rat medial prefrontal cortex. Neurotox Res 26 299-306 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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- GO:0045944 ! positive regulation of transcription by RNA polymerase II
- GO:1905528 ! positive regulation of Golgi lumen acidification
- GO:0060736 ! prostate gland growth
- GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process
- GO:0000209 ! protein polyubiquitination
- GO:0016567 ! protein ubiquitination
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