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RAT:BAG1
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Bag1 | |
| Protein Name(s) | BAG family molecular chaperone regulator 1
BAG-1 Bcl-2-associated athanogene 1 | |
| External Links | ||
| UniProt | B0K019 | |
| EMBL | BC159418 | |
| RefSeq | NP_001100117.2 NP_001243013.1 | |
| UniGene | Rn.16320 | |
| ProteinModelPortal | B0K019 | |
| SMR | B0K019 | |
| BioGrid | 255722 | |
| DIP | DIP-60384N | |
| STRING | 10116.ENSRNOP00000011455 | |
| PRIDE | B0K019 | |
| GeneID | 297994 | |
| KEGG | rno:297994 | |
| UCSC | RGD:1305203 | |
| CTD | 573 | |
| RGD | 1305203 | |
| eggNOG | NOG72809 | |
| HOGENOM | HOG000286009 | |
| HOVERGEN | HBG000236 | |
| InParanoid | B0K019 | |
| KO | K09555 | |
| PhylomeDB | B0K019 | |
| NextBio | 642929 | |
| PRO | PR:B0K019 | |
| Proteomes | UP000002494 | |
| Genevisible | B0K019 | |
| GO | GO:0005829 GO:0005739 GO:0005634 GO:0048471 GO:0006915 GO:0043066 GO:0042493 GO:0010226 GO:0035094 GO:0014070 | |
| Gene3D | 1.20.58.120 | |
| InterPro | IPR003103 IPR000626 IPR029071 | |
| Pfam | PF02179 PF00240 | |
| SMART | SM00264 SM00213 | |
| SUPFAM | SSF54236 | |
| PROSITE | PS51035 PS50053 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005829 |
cytosol |
ECO:0000314 |
C |
Source: RGD |
Missing: reference | |||||
| GO:0005739 |
mitochondrion |
ECO:0000314 |
C |
Source: RGD |
Missing: reference | |||||
| GO:0005634 |
nucleus |
ECO:0000314 |
C |
Source: RGD |
Missing: reference | |||||
| GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000314 |
C |
Source: RGD |
Missing: reference | |||||
| GO:0043066 |
negative regulation of apoptosis |
ECO:0000315 |
P |
Source: RGD |
Missing: reference | |||||
| GO:0042493 |
response to drug |
ECO:0000270 |
P |
Source: RGD |
Missing: reference | |||||
| GO:0010226 |
response to lithium ion |
ECO:0000270 |
P |
Source: RGD |
Missing: reference | |||||
| GO:0035094 |
response to nicotine |
ECO:0000270 |
P |
Source: RGD |
Missing: reference | |||||
| GO:0006950 |
response to stress |
ECO:0000270 |
P |
Source: RGD |
Missing: reference | |||||
|
enables |
GO:0000774 |
adenyl-nucleotide exchange factor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042493 |
response to drug |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035094 |
response to nicotine |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0014070 |
response to organic cyclic compound |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0014040 |
positive regulation of Schwann cell differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010226 |
response to lithium ion |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050790 |
regulation of catalytic activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0000774 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051087 |
chaperone binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR003103 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yang, L et al. (2007) A novel role for Bcl-2 associated-athanogene-1 (Bag-1) in regulation of the endoplasmic reticulum stress response in mammalian chondrocytes. J. Cell. Biochem. 102 786-800 PubMed GONUTS page
- ↑ 2.0 2.1 Zhou, R et al. (2005) The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers. J. Neurosci. 25 4493-502 PubMed GONUTS page
- ↑ Yamada, K et al. (2005) Expression levels of Rab2, a G protein, and Bag-1, a Bcl-2 binding protein are controlled by withdrawal of nicotine from cultured pheochromocytoma PC12 cells. J Neural Transm (Vienna) 112 633-9 PubMed GONUTS page
- ↑ Weaver, CV & Liu, SP (2008) Differentially expressed pro- and anti-apoptogenic genes in response to benzene exposure: Immunohistochemical localization of p53, Bag, Bad, Bax, Bcl-2, and Bcl-w in lung epithelia. Exp. Toxicol. Pathol. 59 265-72 PubMed GONUTS page
- ↑ Wu, H et al. (2013) Changes in the BAG1 expression of Schwann cells after sciatic nerve crush. J. Mol. Neurosci. 49 512-22 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Hayashi, T et al. (2000) Loss of bag-1 immunoreactivity in rat brain after transient middle cerebral artery occlusion. Brain Res. 852 496-500 PubMed GONUTS page
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