PIG:RELX

Species (Taxon ID)	Sus scrofa (Pig). (9823)
Gene Name(s)	RLN
Protein Name(s)	Prorelaxin Relaxin B chain Relaxin A chain
External Links
UniProt	P01348
EMBL	K01088 J02792
PIR	A90934
RefSeq	NP_999037.1
UniGene	Ssc.82485
PDB	1RLX 2RLX 3RLX 4RLX
PDBsum	1RLX 2RLX 3RLX 4RLX
MINT	MINT-231177
PRIDE	P01348
GeneID	396891
KEGG	ssc:396891
CTD	100329416
eggNOG	NOG40989
HOGENOM	HOG000236342
HOVERGEN	HBG003234
InParanoid	P01348
KO	K05255
Proteomes	UP000008227
GO	GO:0005576
InterPro	IPR016179 IPR022353 IPR022421
Pfam	PF00049
PRINTS	PR02004
SMART	SM00078
SUPFAM	SSF56994
PROSITE	PS00262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0001832	blastocyst growth	PMID:21272344	ECO:0000314			P		In table 4, the authors demonstrate that the addition of porcine relaxin during in vitro culture increases the number of cells in porcine blastocysts.	complete CACAO 1951
	GO:0001556	oocyte maturation	PMID:21272344	ECO:0000314			P		In table 2, the authors demonstrate that the addition of porcine relaxin during in vitro maturation reduced the the proportion of porcine oocytes that retained a germinal vesicle and increased the proportions of porcine oocytes that reach metaphase 2 (MII), both of which are characteristic of oocyte maturation.	complete CACAO 1952
	GO:0034105	positive regulation of tissue remodeling	PMID:8319559	ECO:0000314			P		In figure 2, the authors show that porcine relaxin therapy in ovariectomized gilts restored collagen organization in the cervix during pregnancy.	complete CACAO 1953
	GO:0030317	sperm motility	PMID:16926527	ECO:0000314			P		In figure 1, the authors demonstrate that the addition of porcine relaxin increases the motility of boar spermatozoa.	complete CACAO 1958
	GO:0046326	positive regulation of glucose import	PMID:16926527	ECO:0000314			P		In figure 2, the authors demonstrate that the addition of porcine relaxin increases the glucose import in boar spermatozoa.	complete CACAO 1959
	GO:2000344	positive regulation of acrosome reaction	PMID:16926527	ECO:0000314			P		In figure 1, the authors demonstrate that the addition of porcine relaxin increased the proportion of live boar spermatozoa that had undergone the acrosome reaction.	complete CACAO 2004
	GO:0050679	positive regulation of epithelial cell proliferation	PMID:16956745	ECO:0000314			P		In figure 6, the authors demonstrate that porcine relaxin increases the proportion of cells that are positive for proliferating cell nuclear antigen, indicating cell proliferation.	complete CACAO 2051
	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	PMID:16956745	ECO:0000315			P		Fig. 6	complete
involved_in	GO:2000344	positive regulation of acrosome reaction	PMID:16926527	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001556	oocyte maturation	PMID:21272344	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001832	blastocyst growth	PMID:21272344	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030317	flagellated sperm motility	PMID:16926527	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046326	positive regulation of glucose import	PMID:16926527	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	PMID:16956745	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005179	P		Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016179 InterPro:IPR022421	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016179 InterPro:IPR022421	C		Seeded From UniProt	complete
enables	GO:0005179	hormone activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0372	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
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References

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