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PIG:RELX
Contents
Species (Taxon ID) | Sus scrofa (Pig). (9823) | |
Gene Name(s) | RLN | |
Protein Name(s) | Prorelaxin
Relaxin B chain Relaxin A chain | |
External Links | ||
UniProt | P01348 | |
EMBL | K01088 J02792 | |
PIR | A90934 | |
RefSeq | NP_999037.1 | |
UniGene | Ssc.82485 | |
PDB | 1RLX 2RLX 3RLX 4RLX | |
PDBsum | 1RLX 2RLX 3RLX 4RLX | |
MINT | MINT-231177 | |
PRIDE | P01348 | |
GeneID | 396891 | |
KEGG | ssc:396891 | |
CTD | 100329416 | |
eggNOG | NOG40989 | |
HOGENOM | HOG000236342 | |
HOVERGEN | HBG003234 | |
InParanoid | P01348 | |
KO | K05255 | |
Proteomes | UP000008227 | |
GO | GO:0005576 | |
InterPro | IPR016179 IPR022353 IPR022421 | |
Pfam | PF00049 | |
PRINTS | PR02004 | |
SMART | SM00078 | |
SUPFAM | SSF56994 | |
PROSITE | PS00262 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0001832 |
blastocyst growth |
ECO:0000314 |
P |
In table 4, the authors demonstrate that the addition of porcine relaxin during in vitro culture increases the number of cells in porcine blastocysts. |
complete | |||||
GO:0001556 |
oocyte maturation |
ECO:0000314 |
P |
In table 2, the authors demonstrate that the addition of porcine relaxin during in vitro maturation reduced the the proportion of porcine oocytes that retained a germinal vesicle and increased the proportions of porcine oocytes that reach metaphase 2 (MII), both of which are characteristic of oocyte maturation. |
complete | |||||
GO:0034105 |
positive regulation of tissue remodeling |
ECO:0000314 |
P |
In figure 2, the authors show that porcine relaxin therapy in ovariectomized gilts restored collagen organization in the cervix during pregnancy. |
complete | |||||
GO:0030317 |
sperm motility |
ECO:0000314 |
P |
In figure 1, the authors demonstrate that the addition of porcine relaxin increases the motility of boar spermatozoa. |
complete | |||||
GO:0046326 |
positive regulation of glucose import |
ECO:0000314 |
P |
In figure 2, the authors demonstrate that the addition of porcine relaxin increases the glucose import in boar spermatozoa. |
complete | |||||
GO:2000344 |
positive regulation of acrosome reaction |
ECO:0000314 |
P |
In figure 1, the authors demonstrate that the addition of porcine relaxin increased the proportion of live boar spermatozoa that had undergone the acrosome reaction. |
complete | |||||
GO:0050679 |
positive regulation of epithelial cell proliferation |
ECO:0000314 |
P |
In figure 6, the authors demonstrate that porcine relaxin increases the proportion of cells that are positive for proliferating cell nuclear antigen, indicating cell proliferation. |
complete | |||||
GO:0033148 |
positive regulation of intracellular estrogen receptor signaling pathway |
ECO:0000315 |
P |
Fig. 6 |
complete | |||||
involved_in |
GO:2000344 |
positive regulation of acrosome reaction |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001556 |
oocyte maturation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001832 |
blastocyst growth |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030317 |
flagellated sperm motility |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046326 |
positive regulation of glucose import |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050679 |
positive regulation of epithelial cell proliferation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005179 |
hormone activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005179 |
hormone activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Feugang, JM et al. (2011) In vitro effects of relaxin on gene expression in porcine cumulus-oocyte complexes and developing embryos. Reprod. Biol. Endocrinol. 9 15 PubMed GONUTS page
- ↑ Winn, RJ et al. (1993) Hormonal control of the cervix in pregnant gilts. IV. Relaxin promotes changes in the histological characteristics of the cervix that are associated with cervical softening during late pregnancy in gilts. Endocrinology 133 121-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Miah, AG et al. (2006) Effect of relaxin on acrosome reaction and utilization of glucose in boar spermatozoa. J. Reprod. Dev. 52 773-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Masters, RA et al. (2007) Neonatal porcine endometrial development and epithelial proliferation affected by age and exposure to estrogen and relaxin. Domest. Anim. Endocrinol. 33 335-46 PubMed GONUTS page
p
- GO:0033148 ! positive regulation of intracellular estrogen receptor signaling pathway
- GO:0050679 ! positive regulation of epithelial cell proliferation
- GO:2000344 ! positive regulation of acrosome reaction
- GO:0046326 ! positive regulation of D-glucose import
- GO:0034105 ! positive regulation of tissue remodeling