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PMID:21272344

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Citation

Feugang, JM, Greene, JM, Willard, ST and Ryan, PL (2011) In vitro effects of relaxin on gene expression in porcine cumulus-oocyte complexes and developing embryos. Reprod. Biol. Endocrinol. 9:15

Abstract

Relaxin hormone peptide is found in porcine follicular and utero-tubal fluids, but its possible actions during early embryo development are still undetermined. Here, we investigated the effects of porcine relaxin during oocyte maturation and embryo development, and gene expression in the pig.

Links

PubMed PMC3045296 Online version:10.1186/1477-7827-9-15

Keywords

Animals; Cumulus Cells/physiology; Embryonic Development/drug effects; Embryonic Development/genetics; Embryonic Development/physiology; Female; Fertilization in Vitro/veterinary; Follicular Fluid/physiology; Oocytes/drug effects; Oocytes/physiology; Receptors, G-Protein-Coupled/biosynthesis; Receptors, Peptide/biosynthesis; Relaxin/physiology; Sus scrofa; bcl-2-Associated X Protein/genetics; bcl-X Protein/genetics

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

PIG:RELX

GO:0001832: blastocyst growth

ECO:0000314:

P

In table 4, the authors demonstrate that the addition of porcine relaxin during in vitro culture increases the number of cells in porcine blastocysts.

complete
CACAO 1951

PIG:RELX

GO:0001556: oocyte maturation

ECO:0000314:

P

In table 2, the authors demonstrate that the addition of porcine relaxin during in vitro maturation reduced the the proportion of porcine oocytes that retained a germinal vesicle and increased the proportions of porcine oocytes that reach metaphase 2 (MII), both of which are characteristic of oocyte maturation.

complete
CACAO 1952

PIG:RELX

involved_in

GO:0001832: blastocyst growth

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

PIG:RELX

involved_in

GO:0001556: oocyte maturation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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