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PMID:21272344
| Citation |
Feugang, JM, Greene, JM, Willard, ST and Ryan, PL (2011) In vitro effects of relaxin on gene expression in porcine cumulus-oocyte complexes and developing embryos. Reprod. Biol. Endocrinol. 9:15 |
|---|---|
| Abstract |
Relaxin hormone peptide is found in porcine follicular and utero-tubal fluids, but its possible actions during early embryo development are still undetermined. Here, we investigated the effects of porcine relaxin during oocyte maturation and embryo development, and gene expression in the pig. |
| Links |
PubMed PMC3045296 Online version:10.1186/1477-7827-9-15 |
| Keywords |
Animals; Cumulus Cells/physiology; Embryonic Development/drug effects; Embryonic Development/genetics; Embryonic Development/physiology; Female; Fertilization in Vitro/veterinary; Follicular Fluid/physiology; Oocytes/drug effects; Oocytes/physiology; Receptors, G-Protein-Coupled/biosynthesis; Receptors, Peptide/biosynthesis; Relaxin/physiology; Sus scrofa; bcl-2-Associated X Protein/genetics; bcl-X Protein/genetics |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001832: blastocyst growth |
ECO:0000314: |
P |
In table 4, the authors demonstrate that the addition of porcine relaxin during in vitro culture increases the number of cells in porcine blastocysts. |
complete | ||||
| GO:0001556: oocyte maturation |
ECO:0000314: |
P |
In table 2, the authors demonstrate that the addition of porcine relaxin during in vitro maturation reduced the the proportion of porcine oocytes that retained a germinal vesicle and increased the proportions of porcine oocytes that reach metaphase 2 (MII), both of which are characteristic of oocyte maturation. |
complete | ||||
|
involved_in |
GO:0001832: blastocyst growth |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001556: oocyte maturation |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
See also
References
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