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PIG:JUN

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Species (Taxon ID) Sus scrofa (Pig). (9823)
Gene Name(s) JUN
Protein Name(s) Transcription factor AP-1

Activator protein 1 AP1 Proto-oncogene c-Jun V-jun avian sarcoma virus 17 oncogene homolog

External Links
UniProt P56432
EMBL S83515
RefSeq NP_999045.1
UniGene Ssc.97579
ProteinModelPortal P56432
SMR P56432
STRING 9823.ENSSSCP00000004143
GeneID 396913
KEGG ssc:396913
CTD 101863323
eggNOG NOG283376
HOGENOM HOG000006648
HOVERGEN HBG001722
InParanoid P56432
KO K04448
Proteomes UP000008227
GO GO:0005634
GO:0043565
GO:0003700
GO:0006351
Gene3D 1.10.880.10
InterPro IPR004827
IPR015558
IPR005643
IPR002112
IPR008917
PANTHER PTHR11462:SF8
Pfam PF00170
PF03957
PRINTS PR00043
SMART SM00338
SUPFAM SSF47454
PROSITE PS50217
PS00036

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05412

F

Seeded From UniProt

complete

involved_in

GO:0007265

Ras protein signal transduction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05412

P

Seeded From UniProt

complete

involved_in

GO:0051091

positive regulation of DNA-binding transcription factor activity

PMID:25110868[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_regulation_target:(UniProtKB:E5Q8C6)

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

PMID:25110868[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071222

cellular response to lipopolysaccharide

PMID:25110868[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:25110868[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:25110868[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:25110868[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_regulation_target:(ENSEMBL:ENSSSCG00000006589)

Seeded From UniProt

complete

involved_in

GO:0051726

regulation of cell cycle

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96646
MGI:MGI:96647
PANTHER:PTN000894785

P

Seeded From UniProt

complete

involved_in

GO:0051591

response to cAMP

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
RGD:2943
RGD:2944

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001291
MGI:MGI:96646
MGI:MGI:96647
MGI:MGI:96648
PANTHER:PTN000894784
RGD:2943
UniProtKB:A0A1D8PIL5
UniProtKB:P05412
UniProtKB:P17275
UniProtKB:P17535

P

Seeded From UniProt

complete

involved_in

GO:0045597

positive regulation of cell differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96647
PANTHER:PTN000894785

P

Seeded From UniProt

complete

involved_in

GO:0042493

response to drug

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96646
PANTHER:PTN000894785
RGD:2943
RGD:2944

P

Seeded From UniProt

complete

involved_in

GO:0034097

response to cytokine

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
RGD:2943
RGD:2944

P

Seeded From UniProt

complete

involved_in

GO:0032870

cellular response to hormone stimulus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
RGD:2944

P

Seeded From UniProt

complete

involved_in

GO:0032496

response to lipopolysaccharide

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
RGD:2943
RGD:2945

P

Seeded From UniProt

complete

involved_in

GO:0010033

response to organic substance

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894784
RGD:2943

P

Seeded From UniProt

complete

involved_in

GO:0009612

response to mechanical stimulus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
RGD:2943
RGD:2944
RGD:2945

P

Seeded From UniProt

complete

involved_in

GO:0009314

response to radiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
RGD:2943

P

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96648
PANTHER:PTN000894785
RGD:2943
UniProtKB:P05412
WB:WBGene00012005

F

Seeded From UniProt

complete

part_of

GO:0005667

transcription factor complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001291
MGI:MGI:96646
PANTHER:PTN000894784
ZFIN:ZDB-GENE-030131-7859

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894784
UniProtKB:P05412
UniProtKB:P17275

C

Seeded From UniProt

complete

enables

GO:0003713

transcription coactivator activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894785
UniProtKB:P05412

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001291
PANTHER:PTN000894784

F

Seeded From UniProt

complete

enables

GO:0000978

RNA polymerase II proximal promoter sequence-specific DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96647
MGI:MGI:96648
PANTHER:PTN000894784

F

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894784
RGD:2943

C

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000894784
SGD:S000000735

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002112
InterPro:IPR008917
InterPro:IPR015558

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002112
InterPro:IPR004827
InterPro:IPR015558

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002112
InterPro:IPR004827
InterPro:IPR008917
InterPro:IPR015558

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Li, X et al. (2014) The inflammation-related gene S100A12 is positively regulated by C/EBPβ and AP-1 in pigs. Int J Mol Sci 15 13802-16 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page