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MOUSE:IRF5

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Irf5
Protein Name(s) Interferon regulatory factor 5

IRF-5

External Links
UniProt P56477
EMBL AF028725
CCDS CCDS19962.1
RefSeq NP_001239311.1
NP_036187.1
XP_006505160.1
UniGene Mm.6479
ProteinModelPortal P56477
SMR P56477
BioGrid 205111
IntAct P56477
MINT MINT-1565953
STRING 10090.ENSMUSP00000004392
PhosphoSite P56477
PaxDb P56477
PRIDE P56477
DNASU 27056
Ensembl ENSMUST00000004392
ENSMUST00000163511
GeneID 27056
KEGG mmu:27056
UCSC uc009bdu.2
CTD 3663
MGI MGI:1350924
eggNOG NOG45024
HOGENOM HOG000037433
HOVERGEN HBG105715
InParanoid P56477
KO K09446
OMA YDGPRDM
OrthoDB EOG7CCBR1
PhylomeDB P56477
TreeFam TF328512
Reactome REACT_198660
NextBio 305003
PRO PR:P56477
Proteomes UP000000589
Bgee P56477
CleanEx MM_IRF5
ExpressionAtlas P56477
Genevestigator P56477
GO GO:0005737
GO:0005634
GO:0000975
GO:0003700
GO:0051607
GO:0045087
GO:0043065
GO:0045944
GO:0032495
GO:0032494
GO:0006351
Gene3D 1.10.10.10
2.60.200.10
InterPro IPR019817
IPR001346
IPR019471
IPR029838
IPR017855
IPR008984
IPR011991
PANTHER PTHR11949:SF10
Pfam PF00605
PF10401
PRINTS PR00267
SMART SM00348
SUPFAM SSF49879
PROSITE PS00601
PS51507

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0051607

defense response to virus

PMID:20451243[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1096873
MGI:MGI:1859179
MGI:MGI:96395
MGI:MGI:96590
PANTHER:PTN000942746
RGD:2920
UniProtKB:O14896
UniProtKB:P10914
UniProtKB:P14316
UniProtKB:Q02556
UniProtKB:Q13568
UniProtKB:Q14653
UniProtKB:Q15306
UniProtKB:Q92985
ZFIN:ZDB-GENE-041114-13
ZFIN:ZDB-GENE-070912-330

C

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1096873
MGI:MGI:1350924
MGI:MGI:1859179
MGI:MGI:1859212
MGI:MGI:96395
MGI:MGI:96590
PANTHER:PTN000942747
UniProtKB:P10914
UniProtKB:P14316
UniProtKB:Q02556
UniProtKB:Q92985
ZFIN:ZDB-GENE-040718-367
ZFIN:ZDB-GENE-070912-330

P

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1859212
PANTHER:PTN000942746
UniProtKB:P10914
UniProtKB:P14316
UniProtKB:Q02556
UniProtKB:Q14653
UniProtKB:Q15306
UniProtKB:Q92985
ZFIN:ZDB-GENE-070912-330

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043065

positive regulation of apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032495

response to muramyl dipeptide

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032494

response to peptidoglycan

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13568

C

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

F

Seeded From UniProt

complete

involved_in

GO:0043065

positive regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

F

Seeded From UniProt

complete

involved_in

GO:0032495

response to muramyl dipeptide

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

P

Seeded From UniProt

complete

involved_in

GO:0032494

response to peptidoglycan

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q13568
ensembl:ENSP00000418037

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019471
InterPro:IPR019817

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019471
InterPro:IPR019817

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029838

P

Seeded From UniProt

complete

involved_in

GO:0019221

cytokine-mediated signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029838

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001346

F

Seeded From UniProt

complete

involved_in

GO:0051607

defense response to virus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029838

P

Seeded From UniProt

complete

involved_in

GO:0002376

immune system process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0045087

innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0399

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0051607

defense response to virus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0051

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Dixit, E et al. (2010) Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141 668-81 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page