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MOUSE:COIL

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Coil (synonyms: CLN80)
Protein Name(s) Coilin

p80-coilin

External Links
UniProt Q5SU73
EMBL AF208663
AY047705
AY047703
AY047704
AL646096
CU407331
CH466556
BC031167
AK167167
UniGene Mm.268004
ProteinModelPortal Q5SU73
IntAct Q5SU73
MINT MINT-4116771
STRING 10090.ENSMUSP00000103530
iPTMnet Q5SU73
PhosphoSitePlus Q5SU73
EPD Q5SU73
MaxQB Q5SU73
PaxDb Q5SU73
PRIDE Q5SU73
MGI MGI:104842
eggNOG ENOG410IHAK
ENOG41121C6
HOGENOM HOG000059586
HOVERGEN HBG007989
InParanoid Q5SU73
OrthoDB EOG091G0B3V
PhylomeDB Q5SU73
ChiTaRS Coil
PRO PR:Q5SU73
Proteomes UP000000589
Bgee ENSMUSG00000033983
Genevisible Q5SU73
GO GO:0015030
GO:0001674
GO:0001650
GO:0016020
GO:0016604
GO:0005730
GO:0005654
GO:0005634
GO:0015036
GO:0042802
GO:0008022
InterPro IPR024822
IPR031722
PANTHER PTHR15197:SF2
Pfam PF15862

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

F

Seeded From UniProt

complete

GO:0005634

nucleus

PMID:28337219[1]

ECO:0000314

C

Figure 3. "Surprisingly, in olfactory bulbs (Figures 3(a)(A), 3(a)(B), and 3(b)(A)), high levels of coilin were noted in the highly DAPI-dense nuclear regions surrounding single CBs (Figures 3(b)(B)–3(b)(D)). This nuclear distribution pattern of coilin was observed in individual nuclei of the granular layer of the OBs in adult brain (Figures 3(b)(A)–3(b)(C); see magnification in Figure 3(b)(D) and quantification in Figure 3(b)(E))." Mouse, coilin.

complete
CACAO 12764

part_of

GO:0016604

nuclear body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

C

Seeded From UniProt

complete

enables

GO:0015036

disulfide oxidoreductase activity

PMID:17284516[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0015030

Cajal body

PMID:7768196[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0015030

Cajal body

PMID:11470819[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0015030

Cajal body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

C

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:62031

F

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

C

Seeded From UniProt

complete

part_of

GO:0001674

female germ cell nucleus

PMID:7768196[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001650

fibrillar center

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P38432

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015036

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0015030

Cajal body

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0031

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Krejčí, J et al. (2017) Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by Coilin Downregulation and the Accumulation of Cajal Bodies in Nucleoli. Stem Cells Int 2017 1021240 PubMed GONUTS page
  2. Naetar, N et al. (2007) LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit. J. Cell. Sci. 120 737-47 PubMed GONUTS page
  3. 3.0 3.1 Ferreira, J & Carmo-Fonseca, M (1995) The biogenesis of the coiled body during early mouse development. Development 121 601-12 PubMed GONUTS page
  4. Tucker, KE et al. (2001) Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product. J. Cell Biol. 154 293-307 PubMed GONUTS page