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MOUSE:CHFR
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Chfr | |
Protein Name(s) | E3 ubiquitin-protein ligase CHFR
Checkpoint with forkhead and RING finger domains protein | |
External Links | ||
UniProt | Q810L3 | |
EMBL | AK052473 AK077629 AK147892 AK154038 AK155295 AK155525 AK169182 AK169193 CH466529 BC049792 | |
CCDS | CCDS19522.1 CCDS71637.1 | |
RefSeq | NP_001276506.1 NP_001276507.1 NP_001276508.1 NP_001276509.1 NP_766305.2 | |
UniGene | Mm.30264 | |
ProteinModelPortal | Q810L3 | |
SMR | Q810L3 | |
BioGrid | 231141 | |
PhosphoSite | Q810L3 | |
MaxQB | Q810L3 | |
PRIDE | Q810L3 | |
Ensembl | ENSMUST00000014812 ENSMUST00000112519 | |
GeneID | 231600 | |
KEGG | mmu:231600 | |
UCSC | uc008ypv.2 uc008ypw.2 uc008ypz.2 | |
CTD | 55743 | |
MGI | MGI:2444898 | |
eggNOG | NOG253207 | |
GeneTree | ENSGT00400000022306 | |
HOVERGEN | HBG048005 | |
InParanoid | Q810L3 | |
KO | K10644 | |
OMA | LYWGCAR | |
OrthoDB | EOG78D7JS | |
PhylomeDB | Q810L3 | |
TreeFam | TF330957 | |
UniPathway | UPA00143 | |
ChiTaRS | Chfr | |
NextBio | 380643 | |
PRO | PR:Q810L3 | |
Proteomes | UP000000589 | |
Bgee | Q810L3 | |
CleanEx | MM_CHFR | |
Genevestigator | Q810L3 | |
GO | GO:0005634 GO:0016605 GO:0016874 GO:0000166 GO:0061630 GO:0008270 GO:0000278 GO:0007093 GO:0007067 GO:0032436 GO:0031398 GO:0031648 GO:0000209 GO:0006511 | |
Gene3D | 2.60.200.20 3.30.40.10 | |
InterPro | IPR000253 IPR008984 IPR001841 IPR013083 IPR017907 | |
Pfam | PF00498 PF13639 | |
SMART | SM00240 SM00184 | |
SUPFAM | SSF49879 | |
PROSITE | PS50006 PS00518 PS50089 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0016605 |
PML body |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007093 |
mitotic cell cycle checkpoint |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016567 |
protein ubiquitination |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2444898 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007093 |
mitotic cell cycle checkpoint |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000412551 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2444898 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000412551 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000412551 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0061630 |
ubiquitin protein ligase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3576266 |
F |
has_direct_input:(MGI:MGI:894678) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0031648 |
protein destabilization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0031398 |
positive regulation of protein ubiquitination |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0019941 |
modification-dependent protein catabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016605 |
PML body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007093 |
mitotic cell cycle checkpoint |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0000278 |
mitotic cell cycle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3576266 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000209 |
protein polyubiquitination |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0000209 |
protein polyubiquitination |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019941 |
modification-dependent protein catabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016605 |
PML body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007093 |
mitotic cell cycle checkpoint |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000209 |
protein polyubiquitination |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q96EP1 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051301 |
cell division |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016605 |
PML body |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016567 |
protein ubiquitination |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00143 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Yu, X et al. (2005) Chfr is required for tumor suppression and Aurora A regulation. Nat. Genet. 37 401-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Jung, I et al. (2012) SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components. Biochem. Biophys. Res. Commun. 418 512-7 PubMed GONUTS page
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