HUMAN:TNR1B

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	TNFRSF1B (synonyms: TNFBR, TNFR2)
Protein Name(s)	Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor receptor 2 TNF-R2 Tumor necrosis factor receptor type II TNF-RII TNFR-II p75 p80 TNF-alpha receptor Tumor necrosis factor receptor superfamily member 1b, membrane form Tumor necrosis factor-binding protein 2 TBP-2 TBPII
External Links
UniProt	P20333
EMBL	M55994 M32315 U52165 U52156 U52157 U52158 U52159 U52160 U52161 U52162 U52163 U52164 AY148473 BT019927 AY264804 AY342040 AL031276 AL357835 AL357835 AL031276 CH471130 BC052977 S63368 M35857 AB030950
CCDS	CCDS145.1
PIR	A35356
RefSeq	NP_001057.1
UniGene	Hs.256278
PDB	1CA9 3ALQ
PDBsum	1CA9 3ALQ
ProteinModelPortal	P20333
SMR	P20333
BioGrid	112987
DIP	DIP-78N
IntAct	P20333
MINT	MINT-134958
STRING	9606.ENSP00000365435
ChEMBL	CHEMBL1250356
DrugBank	DB00005
iPTMnet	P20333
PhosphoSitePlus	P20333
BioMuta	TNFRSF1B
DMDM	21264534
PaxDb	P20333
PeptideAtlas	P20333
PRIDE	P20333
DNASU	7133
Ensembl	ENST00000376259
GeneID	7133
KEGG	hsa:7133
UCSC	uc001att.4
CTD	7133
DisGeNET	7133
GeneCards	MIR7846 TNFRSF1B
HGNC	HGNC:11917
HPA	HPA004796
MalaCards	TNFRSF1B
MIM	191191
neXtProt	NX_P20333
OpenTargets	ENSG00000028137
PharmGKB	PA36610
eggNOG	ENOG410IJ06 ENOG410YPQW
GeneTree	ENSGT00760000119204
HOGENOM	HOG000132845
HOVERGEN	HBG054237
InParanoid	P20333
KO	K05141
OMA	NCVIMTQ
OrthoDB	EOG091G03XW
PhylomeDB	P20333
TreeFam	TF331157
Reactome	[www.reactome.org/content/detail/R-HSA-5668541 R-HSA-5668541] [www.reactome.org/content/detail/R-HSA-5669034 R-HSA-5669034] [www.reactome.org/content/detail/R-HSA-6783783 R-HSA-6783783] [www.reactome.org/content/detail/R-HSA-6785807 R-HSA-6785807] [www.reactome.org/content/detail/R-HSA-6798695 R-HSA-6798695]
SIGNOR	P20333
ChiTaRS	TNFRSF1B
EvolutionaryTrace	P20333
GeneWiki	TNFRSF1B
GenomeRNAi	7133
PMAP-CutDB	P20333
PRO	PR:P20333
Proteomes	UP000005640
Bgee	ENSG00000028137
CleanEx	HS_TNFRSF1B
ExpressionAtlas	P20333
Genevisible	P20333
GO	GO:0005576 GO:0005887 GO:0045121 GO:0043025 GO:0005634 GO:0048471 GO:0005886 GO:0035579 GO:0043196 GO:0005031 GO:0031625 GO:0007568 GO:0097190 GO:0071363 GO:0071222 GO:0097191 GO:0006955 GO:0006954 GO:0008630 GO:0007275 GO:0050728 GO:0043312 GO:0051044 GO:0042981 GO:0042127 GO:0050779 GO:0033209
CDD	cd10577
InterPro	IPR001368 IPR020411 IPR033996
Pfam	PF00020
PRINTS	PR01919
SMART	SM00208
PROSITE	PS00652 PS50050

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(UBERON:0002137) part_of:(GO:0003176)	Seeded From UniProt	complete
involved_in	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(UBERON:0002146) part_of:(GO:0003177)	Seeded From UniProt	complete
involved_in	GO:0003332	negative regulation of extracellular matrix constituent secretion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(UBERON:0002137) part_of:(GO:0003176)	Seeded From UniProt	complete
involved_in	GO:0003177	pulmonary valve development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P		Seeded From UniProt	complete
involved_in	GO:0003176	aortic valve development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P		Seeded From UniProt	complete
involved_in	GO:2001141	regulation of RNA biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0002453) regulates_o_occurs_in:(CL:0000128) occurs_in:(UBERON:0002240)	Seeded From UniProt	complete
involved_in	GO:1901215	negative regulation of neuron death	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000128) occurs_in:(CL:0002453) part_of:(GO:0150079) regulates_o_occurs_in:(CL:0000540) part_of:(GO:0150098)	Seeded From UniProt	complete
involved_in	GO:0150098	glial cell-neuron signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	regulates:(GO:0150076) has_start_location:(CL:0000128) has_start_location:(CL:0002453) has_end_location:(CL:0000540)	Seeded From UniProt	complete
involved_in	GO:0150079	negative regulation of neuroinflammatory response	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000128) occurs_in:(CL:0002453)	Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000128) occurs_in:(CL:0002453) part_of:(GO:0150079) regulates_o_occurs_in:(CL:0000128)\|occurs_in(CL:0000128) occurs_in:(CL:0002453) part_of:(GO:0150079) regulates_o_occurs_in:(CL:0002453)	Seeded From UniProt	complete
involved_in	GO:0048714	positive regulation of oligodendrocyte differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0002453) regulates_o_occurs_in:(CL:0000128)	Seeded From UniProt	complete
involved_in	GO:0031643	positive regulation of myelination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000128) occurs_in:(CL:0002453) regulates_o_occurs_in:(CL:0000540) part_of:(GO:0150098)	Seeded From UniProt	complete
enables	GO:0043120	tumor necrosis factor binding	PMID:9435233^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P01375	F		Seeded From UniProt	complete
involved_in	GO:0150077	regulation of neuroinflammatory response	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000129) regulates_o_occurs_in:(CL:0000129) occurs_in:(UBERON:0002240) regulates_o_occurs_in:(UBERON:0002240)\|occurs_in(CL:0000129) occurs_in:(CL:0000235) regulates_o_occurs_in:(UBERON:0002106) regulates:(GO:0042098)\|occurs_in(CL:0000129) occurs_in:(CL:0000235) regulates_o_occurs_in:(UBERON:0002106) regulates:(GO:0002369)	Seeded From UniProt	complete
involved_in	GO:0042129	regulation of T cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000129) occurs_in:(CL:0000235) regulates_o_occurs_in:(UBERON:0002106)	Seeded From UniProt	complete
involved_in	GO:0031641	regulation of myelination	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000129) regulates_o_occurs_in:(UBERON:0006134) occurs_in:(UBERON:0002240) regulates_o_occurs_in:(UBERON:0002240) part_of:(GO:0150077)	Seeded From UniProt	complete
involved_in	GO:0002739	regulation of cytokine secretion involved in immune response	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000129) regulates_o_occurs_in:(CL:0000084) occurs_in:(UBERON:0002240) regulates_o_occurs_in:(UBERON:0002240) part_of:(GO:0150077)	Seeded From UniProt	complete
involved_in	GO:0002724	regulation of T cell cytokine production	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P25119	P	occurs_in:(CL:0000129) occurs_in:(CL:0000235) regulates_o_occurs_in:(UBERON:0002106)	Seeded From UniProt	complete
involved_in	GO:0071222	cellular response to lipopolysaccharide	PMID:22480688^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	PMID:22480688^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:17010968^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	PMID:11279055^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q12933	F		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	PMID:11279055^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O94972	F		Seeded From UniProt	complete
involved_in	GO:2001141	regulation of RNA biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:1902339	positive regulation of apoptotic process involved in morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:1901215	negative regulation of neuron death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0150098	glial cell-neuron signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0150079	negative regulation of neuroinflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0150077	regulation of neuroinflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0097191	extrinsic apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0060548	negative regulation of cell death	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0050779	RNA destabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0050728	negative regulation of inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0048714	positive regulation of oligodendrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	C		Seeded From UniProt	complete
involved_in	GO:0042129	regulation of T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0031643	positive regulation of myelination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0031641	regulation of myelination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	C		Seeded From UniProt	complete
involved_in	GO:0010614	negative regulation of cardiac muscle hypertrophy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0007166	cell surface receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
enables	GO:0005031	tumor necrosis factor-activated receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	F		Seeded From UniProt	complete
involved_in	GO:0003332	negative regulation of extracellular matrix constituent secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0003177	pulmonary valve development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0003176	aortic valve development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0002739	regulation of cytokine secretion involved in immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0002724	regulation of T cell cytokine production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P25119 ensembl:ENSMUSP00000030336	P		Seeded From UniProt	complete
involved_in	GO:0071363	cellular response to growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	P		Seeded From UniProt	complete
involved_in	GO:0071356	cellular response to tumor necrosis factor	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	P		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	C		Seeded From UniProt	complete
part_of	GO:0043196	varicosity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	C		Seeded From UniProt	complete
involved_in	GO:0032496	response to lipopolysaccharide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	C		Seeded From UniProt	complete
involved_in	GO:0007568	aging	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	P		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	C		Seeded From UniProt	complete
enables	GO:0005031	tumor necrosis factor-activated receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80WY6 ensembl:ENSRNOP00000022478	F		Seeded From UniProt	complete
enables	GO:0005031	tumor necrosis factor-activated receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020411 InterPro:IPR033996	F		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033996	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020411	C		Seeded From UniProt	complete
involved_in	GO:0033209	tumor necrosis factor-mediated signaling pathway	PMID:24966471^[5] Reactome:R-HSA-5668541	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0002947	tumor necrosis factor receptor superfamily complex	PMID:24966471^[5]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	part_of:(GO:0016020)	Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:24966471^[5]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005031	tumor necrosis factor-activated receptor activity	PMID:8702885^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	Reactome:R-HSA-6798695	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0035579	specific granule membrane	Reactome:R-HSA-6799350	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	Reactome:R-HSA-6785807 Reactome:R-HSA-6783783	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-8937654 Reactome:R-HSA-6799350 Reactome:R-HSA-6790022 Reactome:R-HSA-5669097 Reactome:R-HSA-5668481 Reactome:R-HSA-5668467 Reactome:R-HSA-5668454 Reactome:R-HSA-5668417 Reactome:R-HSA-5668414 Reactome:R-HSA-5668404	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0053	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Grell, M et al. (1998) The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor. Proc. Natl. Acad. Sci. U.S.A. 95 570-5 PubMed GONUTS page
↑ ^2.0 ^2.1 English, WR et al. (2012) LPS activates ADAM9 dependent shedding of ACE from endothelial cells. Biochem. Biophys. Res. Commun. 421 70-5 PubMed GONUTS page
↑ Tellier, E et al. (2006) The shedding activity of ADAM17 is sequestered in lipid rafts. Exp. Cell Res. 312 3969-80 PubMed GONUTS page
↑ ^4.0 ^4.1 Zapata, JM et al. (2001) A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains. J. Biol. Chem. 276 24242-52 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Olmos, G & Lladó, J (2014) Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity. Mediators Inflamm. 2014 861231 PubMed GONUTS page
↑ Santee, SM & Owen-Schaub, LB (1996) Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization. J. Biol. Chem. 271 21151-9 PubMed GONUTS page

[PMID:9435233-1] Grell, M et al. (1998) The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor. Proc. Natl. Acad. Sci. U.S.A. 95 570-5 PubMed GONUTS page

[PMID:22480688-2] 2.0 ^2.1 English, WR et al. (2012) LPS activates ADAM9 dependent shedding of ACE from endothelial cells. Biochem. Biophys. Res. Commun. 421 70-5 PubMed GONUTS page

[PMID:17010968-3] Tellier, E et al. (2006) The shedding activity of ADAM17 is sequestered in lipid rafts. Exp. Cell Res. 312 3969-80 PubMed GONUTS page

[PMID:11279055-4] 4.0 ^4.1 Zapata, JM et al. (2001) A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains. J. Biol. Chem. 276 24242-52 PubMed GONUTS page

[PMID:24966471-5] 5.0 ^5.1 ^5.2 Olmos, G & Lladó, J (2014) Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity. Mediators Inflamm. 2014 861231 PubMed GONUTS page

[PMID:8702885-6] Santee, SM & Owen-Schaub, LB (1996) Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization. J. Biol. Chem. 271 21151-9 PubMed GONUTS page

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HUMAN:TNR1B

Contents

Annotations

Notes

References

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