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HUMAN:TF2L1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) TFCP2L1 (synonyms: CRTR1, LBP9)
Protein Name(s) Transcription factor CP2-like protein 1

CP2-related transcriptional repressor 1 CRTR-1 Transcription factor LBP-9

External Links
UniProt Q9NZI6
EMBL AF198488
AC013399
AC079988
BC064698
CCDS CCDS2134.1
RefSeq NP_055368.1
UniGene Hs.156471
ProteinModelPortal Q9NZI6
SMR Q9NZI6
BioGrid 118929
IntAct Q9NZI6
STRING 9606.ENSP00000263707
PhosphoSite Q9NZI6
DMDM 74734729
MaxQB Q9NZI6
PaxDb Q9NZI6
PRIDE Q9NZI6
DNASU 29842
Ensembl ENST00000263707
GeneID 29842
KEGG hsa:29842
UCSC uc002tmx.3
CTD 29842
GeneCards GC02M121974
HGNC HGNC:17925
HPA HPA029708
MIM 609785
neXtProt NX_Q9NZI6
PharmGKB PA134980544
eggNOG NOG275458
GeneTree ENSGT00760000119235
HOGENOM HOG000230625
HOVERGEN HBG053805
InParanoid Q9NZI6
KO K09275
OMA DVAYQVN
OrthoDB EOG7FBRHB
PhylomeDB Q9NZI6
TreeFam TF314132
ChiTaRS TFCP2L1
GenomeRNAi 29842
NextBio 52375
PRO PR:Q9NZI6
Proteomes UP000005640
Bgee Q9NZI6
CleanEx HS_TFCP2L1
ExpressionAtlas Q9NZI6
Genevestigator Q9NZI6
GO GO:0005737
GO:0016020
GO:0005634
GO:0003677
GO:0003700
GO:0003714
GO:0000902
GO:0007028
GO:0008340
GO:0002070
GO:0007565
GO:0000122
GO:0045927
GO:0006357
GO:0007431
GO:0006694
GO:0006351
InterPro IPR007604
IPR013761
Pfam PF04516
SUPFAM SSF47769

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016563

transcription activator activity

PMID:20661472[1]

ECO:0000314

F

Figure 1A

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[2]

ECO:0000255

match to sequence model evidence used in manual assertion

InterPro:IPR007604

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000113

ECO:0005556

multiple sequence alignment evidence used in manual assertion

UniProtKB:A0A0G2JTJ9

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0259211
MGI:MGI:2182540
MGI:MGI:2182543
MGI:MGI:2655333
PANTHER:PTN000867451
UniProtKB:Q6ISB3
UniProtKB:Q9NZI5

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000867451
UniProtKB:Q12800

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0259211
MGI:MGI:2182540
MGI:MGI:2182543
MGI:MGI:2444691
MGI:MGI:2655333
PANTHER:PTN000112980
UniProtKB:Q12800
UniProtKB:Q6ISB3
UniProtKB:Q8TE85
UniProtKB:Q9NZI5

C

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0259211
MGI:MGI:2182543
PANTHER:PTN000867451

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0001650

fibrillar center

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045927

positive regulation of growth

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

C

Seeded From UniProt

complete

involved_in

GO:0008340

determination of adult lifespan

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

involved_in

GO:0007431

salivary gland development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

involved_in

GO:0007028

cytoplasm organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

C

Seeded From UniProt

complete

involved_in

GO:0002070

epithelial cell maturation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

F

Seeded From UniProt

complete

involved_in

GO:0000902

cell morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q3UNW5
ensembl:ENSMUSP00000027629

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037598
InterPro:IPR040167

F

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037598
InterPro:IPR040167

P

Seeded From UniProt

complete

involved_in

GO:0007565

female pregnancy

PMID:10644752[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006694

steroid biosynthetic process

PMID:10644752[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:10644752[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003714

transcription corepressor activity

PMID:10644752[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:10644752[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. To, S et al. (2010) Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation. PLoS ONE 5 e11702 PubMed GONUTS page
  2. 2.0 2.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Huang, N & Miller, WL (2000) Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc. J. Biol. Chem. 275 2852-8 PubMed GONUTS page