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HUMAN:SOX13

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SOX13
Protein Name(s) Transcription factor SOX-13

Islet cell antigen 12 SRY (Sex determining region Y)-box 13 Type 1 diabetes autoantigen ICA12

External Links
UniProt Q9UN79
EMBL AF083105
AF098915
AF116571
AK304192
AF149301
AL592146
CH471067
BC106038
CCDS CCDS44299.1
RefSeq NP_005677.2
UniGene Hs.201671
ProteinModelPortal Q9UN79
SMR Q9UN79
BioGrid 114948
IntAct Q9UN79
MINT MINT-1179847
STRING 9606.ENSP00000272193
PhosphoSite Q9UN79
DMDM 288558840
MaxQB Q9UN79
PaxDb Q9UN79
PRIDE Q9UN79
DNASU 9580
Ensembl ENST00000367204
ENST00000618875
GeneID 9580
KEGG hsa:9580
UCSC uc001ham.3
CTD 9580
GeneCards GC01P204043
HGNC HGNC:11192
HPA HPA051790
MIM 604748
neXtProt NX_Q9UN79
PharmGKB PA36029
eggNOG NOG275089
GeneTree ENSGT00760000119274
HOVERGEN HBG003915
InParanoid Q9UN79
KO K09269
OMA CDVDGSR
OrthoDB EOG7R56S9
PhylomeDB Q9UN79
TreeFam TF320471
SignaLink Q9UN79
ChiTaRS SOX13
GeneWiki SOX13
GenomeRNAi 9580
NextBio 35933
PRO PR:Q9UN79
Proteomes UP000005640
Bgee Q9UN79
CleanEx HS_SOX13
ExpressionAtlas Q9UN79
Genevestigator Q9UN79
GO GO:0005634
GO:0043565
GO:0003700
GO:0009653
GO:0045586
GO:0006351
Gene3D 1.10.30.10
InterPro IPR009071
IPR029547
PANTHER PTHR10270:SF109
Pfam PF00505
SMART SM00398
SUPFAM SSF47095
PROSITE PS50118

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:19274049[1]

ECO:0000255

match to sequence model evidence used in manual assertion

InterPro:IPR009071

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

GO_REF:0000113

ECO:0005556

multiple sequence alignment evidence used in manual assertion

UniProtKB:Q04890

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q04891

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q04891

C

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98367
MGI:MGI:98368
PANTHER:PTN000030844

P

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98367
MGI:MGI:98368
PANTHER:PTN000030844

P

Seeded From UniProt

complete

involved_in

GO:0045165

cell fate commitment

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98367
MGI:MGI:98368
PANTHER:PTN000030844

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045586

regulation of gamma-delta T cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q04891
ensembl:ENSMUSP00000119729

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q04891
ensembl:ENSMUSP00000119729

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q04891
ensembl:ENSMUSP00000119729

C

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q04891
ensembl:ENSMUSP00000119729

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029547

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029547

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029547

F

Seeded From UniProt

complete

involved_in

GO:0009653

anatomical structure morphogenesis

PMID:10198172[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:10198172[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

Reactome:R-HSA-5665608

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Roose, J et al. (1999) The Sox-13 gene: structure, promoter characterization, and chromosomal localization. Genomics 57 301-5 PubMed GONUTS page