HUMAN:RB11A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	RAB11A (synonyms: RAB11)
Protein Name(s)	Ras-related protein Rab-11A Rab-11 YL8
External Links
UniProt	P62491
EMBL	X53143 X56740 AF000231 AF498946 CR407669 CR536493 BT020151 BT020154 AK300008 AK311770 AC011939 AC084854 CH471082 BC013348
CCDS	CCDS10212.1 CCDS58373.1
PIR	S47169
RefSeq	NP_001193765.1 NP_004654.1
UniGene	Hs.321541
PDB	1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P 4D0L 4D0M 4LWZ 4LX0 4UJ3 4UJ4 4UJ5 5C46 5C4G 5EUQ 5EZ5 5FBL 5FBQ 5FBR 5FBV 5FBW 5JCZ
PDBsum	1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P 4D0L 4D0M 4LWZ 4LX0 4UJ3 4UJ4 4UJ5 5C46 5C4G 5EUQ 5EZ5 5FBL 5FBQ 5FBR 5FBV 5FBW 5JCZ
ProteinModelPortal	P62491
SMR	P62491
BioGrid	114299
CORUM	P62491
DIP	DIP-29138N
IntAct	P62491
MINT	MINT-1434585
STRING	9606.ENSP00000261890
DrugBank	DB01864 DB04315
iPTMnet	P62491
PhosphoSitePlus	P62491
SwissPalm	P62491
BioMuta	RAB11A
DMDM	50402542
OGP	P62491
MaxQB	P62491
PaxDb	P62491
PeptideAtlas	P62491
PRIDE	P62491
TopDownProteomics	P62491-1
DNASU	8766
Ensembl	ENST00000261890 ENST00000569896
GeneID	8766
KEGG	hsa:8766
UCSC	uc002apk.4
CTD	8766
DisGeNET	8766
EuPathDB	HostDB:ENSG00000103769.9
GeneCards	RAB11A
HGNC	HGNC:9760
HPA	CAB013097 HPA051697 HPA060686
MIM	605570
neXtProt	NX_P62491
OpenTargets	ENSG00000103769
PharmGKB	PA34101
eggNOG	KOG0087 COG1100
GeneTree	ENSGT00760000118841
HOGENOM	HOG000233968
HOVERGEN	HBG009351
InParanoid	P62491
KO	K07904
OMA	YESVSRW
OrthoDB	EOG091G0O1R
PhylomeDB	P62491
TreeFam	TF300099
Reactome	[www.reactome.org/content/detail/R-HSA-1445148 R-HSA-1445148] [www.reactome.org/content/detail/R-HSA-432040 R-HSA-432040] [www.reactome.org/content/detail/R-HSA-5620912 R-HSA-5620912] [www.reactome.org/content/detail/R-HSA-5620916 R-HSA-5620916] [www.reactome.org/content/detail/R-HSA-8854214 R-HSA-8854214] [www.reactome.org/content/detail/R-HSA-8873719 R-HSA-8873719]
SignaLink	P62491
ChiTaRS	RAB11A
EvolutionaryTrace	P62491
GeneWiki	RAB11A
GenomeRNAi	8766
PRO	PR:P62491
Proteomes	UP000005640
Bgee	ENSG00000103769
CleanEx	HS_RAB11A
ExpressionAtlas	P62491
Genevisible	P62491
GO	GO:0030424 GO:0032154 GO:0031410 GO:0030659 GO:0005829 GO:0070062 GO:0005794 GO:0005739 GO:0005771 GO:0048471 GO:0045335 GO:0005886 GO:0098837 GO:0043234 GO:0055037 GO:0055038 GO:0000922 GO:0005802 GO:0030133 GO:0031982 GO:0005525 GO:0003924 GO:0008017 GO:0031489 GO:0019905 GO:0030953 GO:0097711 GO:0000910 GO:0090150 GO:0072594 GO:0051650 GO:1990182 GO:0032402 GO:0061024 GO:0007080 GO:0090307 GO:0036258 GO:0031175 GO:0098887 GO:0048227 GO:0045773 GO:0010634 GO:0010971 GO:1903078 GO:0043687 GO:0072659 GO:0048169 GO:0010796 GO:0051223 GO:0060627 GO:0003091 GO:0016192
InterPro	IPR027417 IPR005225 IPR001806
Pfam	PF00071
SUPFAM	SSF52540
TIGRFAMs	TIGR00231
PROSITE	PS51419

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0150093	amyloid-beta clearance by transcytosis	PMID:26005850^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q07954,UniProtKB:Q15907	P	has_input:(UniProtKB:P05067:PRO_0000000093) occurs_in:(CL:1001602) has_target_start_location:(GO:0016323) has_target_end_location:(GO:0016324)	Seeded From UniProt	complete
colocalizes_with	GO:0005813	centrosome	PMID:24648492^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002586)	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	PMID:16791210^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007080	mitotic metaphase plate congression	PMID:24561039^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090307	mitotic spindle assembly	PMID:24561039^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030953	astral microtubule organization	PMID:24561039^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	PMID:24561039^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0072594	establishment of protein localization to organelle	PMID:24561039^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_agent:(GO:0055037) occurs_at:(GO:0097431) has_input:(UniProtKB:O14576)\|has_agent(GO:0055037) occurs_at:(GO:0097431) has_input:(UniProtKB:Q9Y6K9)	Seeded From UniProt	complete
involved_in	GO:0051650	establishment of vesicle localization	PMID:24561039^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_agent:(GO:0055037) occurs_at:(GO:0097431)	Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	PMID:24561039^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	happens_during:(GO:0000087)	Seeded From UniProt	complete
colocalizes_with	GO:0005828	kinetochore microtubule	PMID:24561039^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0000922	spindle pole	PMID:24561039^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	PMID:24561039^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	adjacent_to:(GO:0000922) adjacent_to:(GO:0072686) exists_during:(GO:0000087)	Seeded From UniProt	complete
involved_in	GO:0090150	establishment of protein localization to membrane	PMID:24006491^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:Q9Y4I1) occurs_at:(GO:0010008)	Seeded From UniProt	complete
part_of	GO:0031982	vesicle	PMID:18570918^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0031489	myosin V binding	PMID:24006491^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9Y4I1	F		Seeded From UniProt	complete
involved_in	GO:0010634	positive regulation of epithelial cell migration	PMID:22613965^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060627	regulation of vesicle-mediated transport	PMID:22613965^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	PMID:22613965^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[8]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0036258	multivesicular body assembly	PMID:15634213^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1990182	exosomal secretion	PMID:15634213^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010796	regulation of multivesicular body size	PMID:15634213^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005771	multivesicular body	PMID:15634213^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:17562788^[10]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:Q9Y3P9)	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:15326289^[11]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0001088)	Seeded From UniProt	complete
involved_in	GO:0072659	protein localization to plasma membrane	PMID:17082457^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62492	C		Seeded From UniProt	complete
involved_in	GO:0048227	plasma membrane to endosome transport	PMID:11163216^[13]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0045335	phagocytic vesicle	PMID:21255211^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:17462998^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0032402	melanosome transport	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62492	P		Seeded From UniProt	complete
part_of	GO:0032154	cleavage furrow	PMID:15601896^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0031175	neuron projection development	PMID:17082457^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0019905	syntaxin binding	PMID:12145319^[17]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	PMID:19542231^[18]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	PMID:17462998^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:16905101^[19]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:17030804^[20]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:17007872^[21]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:15837192^[22]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0032465	regulation of cytokinesis	PMID:15601896^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:26565907^[23]	ECO:0006063	over expression analysis evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:26565907^[23]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098837	postsynaptic recycling endosome	PMID:26565907^[23]	ECO:0006063	over expression analysis evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0000061) part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098837	postsynaptic recycling endosome	PMID:26565907^[23]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0000061) part_of:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001179699 RGD:619762	P		Seeded From UniProt	complete
part_of	GO:0098837	postsynaptic recycling endosome	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001179699 RGD:619762	C		Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1858202 MGI:MGI:99425 PANTHER:PTN000633981 RGD:619762 UniProtKB:P62491 WB:WBGene00004274 ZFIN:ZDB-GENE-041114-53	C		Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015790 MGI:MGI:1858202 MGI:MGI:99425 PANTHER:PTN000633981 RGD:619762 UniProtKB:P62491 WB:WBGene00004274 ZFIN:ZDB-GENE-041114-53	C		Seeded From UniProt	complete
involved_in	GO:0032482	Rab protein signal transduction	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015790 PANTHER:PTN001292747 RGD:3529 dictyBase:DDB_G0269238	P		Seeded From UniProt	complete
involved_in	GO:0032402	melanosome transport	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1858202 PANTHER:PTN001179699	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1858202 PANTHER:PTN001179699	C		Seeded From UniProt	complete
part_of	GO:0030133	transport vesicle	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001179699 RGD:619762	C		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001179699 UniProtKB:P62491	P		Seeded From UniProt	complete
involved_in	GO:0006887	exocytosis	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000633981 SGD:S000000833 SGD:S000003178	P		Seeded From UniProt	complete
involved_in	GO:0006886	intracellular protein transport	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1914292 PANTHER:PTN001292747 TAIR:locus:2094029 TAIR:locus:2123010 UniProtKB:Q9BW83	P		Seeded From UniProt	complete
part_of	GO:0005768	endosome	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015790 PANTHER:PTN000633980 SGD:S000000833 SGD:S000003178 TAIR:locus:2024276	C		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:21873635^[24]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015790 FB:FBgn0015797 FB:FBgn0016700 MGI:MGI:104606 MGI:MGI:105072 MGI:MGI:105926 MGI:MGI:1861441 MGI:MGI:1931295 MGI:MGI:2443036 MGI:MGI:99425 PANTHER:PTN001292747 PomBase:SPAC1565.06c PomBase:SPAC4C5.02c PomBase:SPBC1703.10 RGD:3529 RGD:619762 SGD:S000000833 SGD:S000001722 SGD:S000001856 SGD:S000001889 SGD:S000003178 SGD:S000004252 SGD:S000004460 SGD:S000004529 SGD:S000005037 SGD:S000005615 TAIR:locus:2041036 TAIR:locus:2082672 TAIR:locus:2202280 TAIR:locus:505006713 UniProtKB:P20336 UniProtKB:P20337 UniProtKB:P20338 UniProtKB:P20339 UniProtKB:P20340 UniProtKB:P51148 UniProtKB:P51149 UniProtKB:P51151 UniProtKB:P61006 UniProtKB:P61019 UniProtKB:P61020 UniProtKB:P61106 UniProtKB:P62491 UniProtKB:P62820 UniProtKB:Q13637 UniProtKB:Q14088 UniProtKB:Q15286 UniProtKB:Q15907 UniProtKB:Q86YS6 UniProtKB:Q96E17 UniProtKB:Q9H082 UniProtKB:Q9H0N0 UniProtKB:Q9H0T7 UniProtKB:Q9UL25 UniProtKB:Q9UL26 UniProtKB:Q9ULC3 WB:WBGene00004268 WB:WBGene00004271 WB:WBGene00006833	F		Seeded From UniProt	complete
part_of	GO:0005802	trans-Golgi network	PMID:15229288^[25]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005815	microtubule organizing center	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	C		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	C		Seeded From UniProt	complete
involved_in	GO:0045773	positive regulation of axon extension	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	P		Seeded From UniProt	complete
involved_in	GO:0032402	melanosome transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62492 ensembl:ENSMUSP00000129163	C		Seeded From UniProt	complete
involved_in	GO:1903078	positive regulation of protein localization to plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	P		Seeded From UniProt	complete
involved_in	GO:0099003	vesicle-mediated transport in synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	P		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	C		Seeded From UniProt	complete
involved_in	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	P		Seeded From UniProt	complete
part_of	GO:0098837	postsynaptic recycling endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	C		Seeded From UniProt	complete
part_of	GO:0098685	Schaffer collateral - CA1 synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	C		Seeded From UniProt	complete
part_of	GO:0055037	recycling endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	C		Seeded From UniProt	complete
involved_in	GO:0051223	regulation of protein transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	P		Seeded From UniProt	complete
involved_in	GO:0048169	regulation of long-term neuronal synaptic plasticity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	P		Seeded From UniProt	complete
part_of	GO:0030133	transport vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	C		Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	F		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62494 ensembl:ENSRNOP00000015598	F		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806	F		Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806 InterPro:IPR005225	F		Seeded From UniProt	complete
involved_in	GO:0097711	ciliary basal body-plasma membrane docking	Reactome:R-HSA-5620912	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0055038	recycling endosome membrane	Reactome:R-HSA-8854759	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0043687	post-translational protein modification	Reactome:R-HSA-597592	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030659	cytoplasmic vesicle membrane	Reactome:R-HSA-432237	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-8870469 Reactome:R-HSA-8870466 Reactome:R-HSA-5638014 Reactome:R-HSA-5638009 Reactome:R-HSA-5623527 Reactome:R-HSA-5623525 Reactome:R-HSA-5623524 Reactome:R-HSA-5623521 Reactome:R-HSA-5623519 Reactome:R-HSA-5623513 Reactome:R-HSA-5620921 Reactome:R-HSA-5617816	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0003091	renal water homeostasis	Reactome:R-HSA-432040	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C		Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C		Seeded From UniProt	complete
part_of	GO:0055038	recycling endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0231	C		Seeded From UniProt	complete
part_of	GO:0045335	phagocytic vesicle	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0206	C		Seeded From UniProt	complete
part_of	GO:0030659	cytoplasmic vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0089	C		Seeded From UniProt	complete
part_of	GO:0032154	cleavage furrow	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0467	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Zhao, Z et al. (2015) Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat. Neurosci. 18 978-87 PubMed GONUTS page
↑ Greer, YE et al. (2014) Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis. Mol. Biol. Cell 25 1629-40 PubMed GONUTS page
↑ Sigal, A et al. (2006) Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nat. Methods 3 525-31 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 ^4.7 ^4.8 ^4.9 Hehnly, H & Doxsey, S (2014) Rab11 endosomes contribute to mitotic spindle organization and orientation. Dev. Cell 28 497-507 PubMed GONUTS page
↑ ^5.0 ^5.1 Lindsay, AJ et al. (2013) Identification and characterization of multiple novel Rab-myosin Va interactions. Mol. Biol. Cell 24 3420-34 PubMed GONUTS page
↑ Bilan, F et al. (2008) Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells. Exp. Cell Res. 314 2199-211 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Kessler, D et al. (2012) The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration. Cell. Physiol. Biochem. 29 647-56 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Savina, A et al. (2005) Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic 6 131-43 PubMed GONUTS page
↑ Fuchs, E et al. (2007) Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. J. Cell Biol. 177 1133-43 PubMed GONUTS page
↑ Pisitkun, T et al. (2004) Identification and proteomic profiling of exosomes in human urine. Proc. Natl. Acad. Sci. U.S.A. 101 13368-73 PubMed GONUTS page
↑ ^12.0 ^12.1 Shirane, M & Nakayama, KI (2006) Protrudin induces neurite formation by directional membrane trafficking. Science 314 818-21 PubMed GONUTS page
↑ Prekeris, R et al. (2000) A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes. Mol. Cell 6 1437-48 PubMed GONUTS page
↑ Seto, S et al. (2011) Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. Traffic 12 407-20 PubMed GONUTS page
↑ ^15.0 ^15.1 Swiatecka-Urban, A et al. (2007) Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells. J. Biol. Chem. 282 23725-36 PubMed GONUTS page
↑ ^16.0 ^16.1 Wilson, GM et al. (2005) The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Mol. Biol. Cell 16 849-60 PubMed GONUTS page
↑ Scales, SJ et al. (2002) Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly. J. Biol. Chem. 277 28271-9 PubMed GONUTS page
↑ Chu, BB et al. (2009) Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface. J. Biol. Chem. 284 22481-90 PubMed GONUTS page
↑ Jagoe, WN et al. (2006) Crystal structure of rab11 in complex with rab11 family interacting protein 2. Structure 14 1273-83 PubMed GONUTS page
↑ Shiba, T et al. (2006) Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1. Proc. Natl. Acad. Sci. U.S.A. 103 15416-21 PubMed GONUTS page
↑ Eathiraj, S et al. (2006) Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes. J. Mol. Biol. 364 121-35 PubMed GONUTS page
↑ Pasqualato, S & Cherfils, J (2005) Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein. Structure 13 533-40 PubMed GONUTS page
↑ ^23.0 ^23.1 ^23.2 ^23.3 Esteves da Silva, M et al. (2015) Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture. Cell Rep 13 933-43 PubMed GONUTS page
↑ ^24.00 ^24.01 ^24.02 ^24.03 ^24.04 ^24.05 ^24.06 ^24.07 ^24.08 ^24.09 ^24.10 ^24.11 ^24.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Coumailleau, F et al. (2004) Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. Mol. Biol. Cell 15 4444-56 PubMed GONUTS page

[PMID:26005850-1] Zhao, Z et al. (2015) Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat. Neurosci. 18 978-87 PubMed GONUTS page

[PMID:24648492-2] Greer, YE et al. (2014) Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis. Mol. Biol. Cell 25 1629-40 PubMed GONUTS page

[PMID:16791210-3] Sigal, A et al. (2006) Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nat. Methods 3 525-31 PubMed GONUTS page

[PMID:24561039-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 ^4.7 ^4.8 ^4.9 Hehnly, H & Doxsey, S (2014) Rab11 endosomes contribute to mitotic spindle organization and orientation. Dev. Cell 28 497-507 PubMed GONUTS page

[PMID:24006491-5] 5.0 ^5.1 Lindsay, AJ et al. (2013) Identification and characterization of multiple novel Rab-myosin Va interactions. Mol. Biol. Cell 24 3420-34 PubMed GONUTS page

[PMID:18570918-6] Bilan, F et al. (2008) Endosomal SNARE proteins regulate CFTR activity and trafficking in epithelial cells. Exp. Cell Res. 314 2199-211 PubMed GONUTS page

[PMID:22613965-7] 7.0 ^7.1 ^7.2 Kessler, D et al. (2012) The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration. Cell. Physiol. Biochem. 29 647-56 PubMed GONUTS page

[PMID:23533145-8] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:15634213-9] 9.0 ^9.1 ^9.2 ^9.3 Savina, A et al. (2005) Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic 6 131-43 PubMed GONUTS page

[PMID:17562788-10] Fuchs, E et al. (2007) Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. J. Cell Biol. 177 1133-43 PubMed GONUTS page

[PMID:15326289-11] Pisitkun, T et al. (2004) Identification and proteomic profiling of exosomes in human urine. Proc. Natl. Acad. Sci. U.S.A. 101 13368-73 PubMed GONUTS page

[PMID:17082457-12] 12.0 ^12.1 Shirane, M & Nakayama, KI (2006) Protrudin induces neurite formation by directional membrane trafficking. Science 314 818-21 PubMed GONUTS page

[PMID:11163216-13] Prekeris, R et al. (2000) A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes. Mol. Cell 6 1437-48 PubMed GONUTS page

[PMID:21255211-14] Seto, S et al. (2011) Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. Traffic 12 407-20 PubMed GONUTS page

[PMID:17462998-15] 15.0 ^15.1 Swiatecka-Urban, A et al. (2007) Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells. J. Biol. Chem. 282 23725-36 PubMed GONUTS page

[PMID:15601896-16] 16.0 ^16.1 Wilson, GM et al. (2005) The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Mol. Biol. Cell 16 849-60 PubMed GONUTS page

[PMID:12145319-17] Scales, SJ et al. (2002) Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly. J. Biol. Chem. 277 28271-9 PubMed GONUTS page

[PMID:19542231-18] Chu, BB et al. (2009) Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface. J. Biol. Chem. 284 22481-90 PubMed GONUTS page

[PMID:16905101-19] Jagoe, WN et al. (2006) Crystal structure of rab11 in complex with rab11 family interacting protein 2. Structure 14 1273-83 PubMed GONUTS page

[PMID:17030804-20] Shiba, T et al. (2006) Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1. Proc. Natl. Acad. Sci. U.S.A. 103 15416-21 PubMed GONUTS page

[PMID:17007872-21] Eathiraj, S et al. (2006) Structural basis for Rab11-mediated recruitment of FIP3 to recycling endosomes. J. Mol. Biol. 364 121-35 PubMed GONUTS page

[PMID:15837192-22] Pasqualato, S & Cherfils, J (2005) Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein. Structure 13 533-40 PubMed GONUTS page

[PMID:26565907-23] 23.0 ^23.1 ^23.2 ^23.3 Esteves da Silva, M et al. (2015) Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture. Cell Rep 13 933-43 PubMed GONUTS page

[PMID:21873635-24] 24.00 ^24.01 ^24.02 ^24.03 ^24.04 ^24.05 ^24.06 ^24.07 ^24.08 ^24.09 ^24.10 ^24.11 ^24.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15229288-25] Coumailleau, F et al. (2004) Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment. Mol. Biol. Cell 15 4444-56 PubMed GONUTS page

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HUMAN:RB11A

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