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HUMAN:MNX1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MNX1 (synonyms: HLXB9) | |
| Protein Name(s) | Motor neuron and pancreas homeobox protein 1
Homeobox protein HB9 | |
| External Links | ||
| UniProt | P50219 | |
| EMBL | U07664 U07663 AC006357 AH007909 | |
| CCDS | CCDS34788.1 CCDS55187.1 | |
| RefSeq | NP_001158727.1 NP_005506.3 | |
| UniGene | Hs.37035 | |
| ProteinModelPortal | P50219 | |
| SMR | P50219 | |
| BioGrid | 109355 | |
| STRING | 9606.ENSP00000252971 | |
| PhosphoSite | P50219 | |
| DMDM | 259016336 | |
| MaxQB | P50219 | |
| PaxDb | P50219 | |
| PRIDE | P50219 | |
| DNASU | 3110 | |
| Ensembl | ENST00000252971 ENST00000543409 | |
| GeneID | 3110 | |
| KEGG | hsa:3110 | |
| UCSC | uc003wna.3 | |
| CTD | 3110 | |
| GeneCards | GC07M156786 | |
| H-InvDB | HIX0033536 | |
| HGNC | HGNC:4979 | |
| MIM | 142994 176450 | |
| neXtProt | NX_P50219 | |
| Orphanet | 1552 | |
| PharmGKB | PA162396041 | |
| eggNOG | NOG322049 | |
| GeneTree | ENSGT00760000119211 | |
| HOGENOM | HOG000234345 | |
| HOVERGEN | HBG051910 | |
| InParanoid | P50219 | |
| KO | K08025 | |
| OrthoDB | EOG7VHT0H | |
| PhylomeDB | P50219 | |
| TreeFam | TF351530 | |
| GeneWiki | MNX1 | |
| GenomeRNAi | 3110 | |
| NextBio | 12341 | |
| PRO | PR:P50219 | |
| Proteomes | UP000005640 | |
| Bgee | P50219 | |
| CleanEx | HS_MNX1 | |
| ExpressionAtlas | P50219 | |
| Genevestigator | P50219 | |
| GO | GO:0005634 GO:0043565 GO:0003700 GO:0009653 GO:0060539 GO:0021904 GO:0031018 GO:0006959 GO:0008045 GO:0021675 GO:0001764 GO:0009791 GO:0006357 GO:0021520 GO:0006351 | |
| Gene3D | 1.10.10.60 | |
| InterPro | IPR017970 IPR001356 IPR020479 IPR009057 | |
| Pfam | PF00046 | |
| PRINTS | PR00024 | |
| SMART | SM00389 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS00027 PS50071 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048812 |
neuron projection morphogenesis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:109160 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031018 |
endocrine pancreas development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:109160 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0021520 |
spinal cord motor neuron cell fate specification |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:109160 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:109160 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005730 |
nucleolus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009653 |
anatomical structure morphogenesis |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006959 |
humoral immune response |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0006351 |
transcription, DNA-templated |
ECO:0000314 |
P |
Figure 2 shows the in vitro transcription and translation of the HB9 coding sequence. |
complete | |||||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Ross, AJ et al. (1998) A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis. Nat. Genet. 20 358-61 PubMed GONUTS page
- ↑ 4.0 4.1 Harrison, KA et al. (1994) A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues. J. Biol. Chem. 269 19968-75 PubMed GONUTS page
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