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HUMAN:MATR3
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MATR3 (synonyms: KIAA0723) | |
| Protein Name(s) | Matrin-3 | |
| External Links | ||
| UniProt | P43243 | |
| EMBL | AB018266 AF117236 AK316420 AC011404 CH471062 CH471062 CH471062 CH471062 BC015031 M63483 | |
| CCDS | CCDS4210.1 CCDS54908.1 | |
| RefSeq | NP_001181883.1 NP_001181884.1 NP_001181885.1 NP_001269207.1 NP_061322.2 NP_954659.1 | |
| UniGene | Hs.268939 Hs.595110 | |
| ProteinModelPortal | P43243 | |
| SMR | P43243 | |
| BioGrid | 115126 | |
| IntAct | P43243 | |
| MINT | MINT-4999417 | |
| STRING | 9606.ENSP00000354346 | |
| PhosphoSite | P43243 | |
| DMDM | 12643409 | |
| MaxQB | P43243 | |
| PaxDb | P43243 | |
| PRIDE | P43243 | |
| DNASU | 9782 | |
| Ensembl | ENST00000361059 ENST00000394805 ENST00000503811 ENST00000509990 ENST00000618441 | |
| GeneID | 9782 | |
| KEGG | hsa:9782 | |
| UCSC | uc003ldt.3 uc011czb.2 | |
| CTD | 9782 | |
| GeneCards | GC05P138609 | |
| HGNC | HGNC:6912 | |
| HPA | CAB033552 HPA036564 HPA036565 | |
| MIM | 164015 606070 | |
| neXtProt | NX_P43243 | |
| Orphanet | 803 600 | |
| PharmGKB | PA30655 | |
| eggNOG | NOG80010 | |
| GeneTree | ENSGT00770000120548 | |
| HOGENOM | HOG000015369 | |
| HOVERGEN | HBG057347 | |
| InParanoid | P43243 | |
| KO | K13213 | |
| OrthoDB | EOG7GJ6C8 | |
| PhylomeDB | P43243 | |
| TreeFam | TF333921 | |
| ChiTaRS | MATR3 | |
| GeneWiki | MATR3 | |
| GenomeRNAi | 9782 | |
| NextBio | 36832 | |
| PMAP-CutDB | P43243 | |
| PRO | PR:P43243 | |
| Proteomes | UP000005640 | |
| Bgee | P43243 | |
| CleanEx | HS_MATR3 | |
| ExpressionAtlas | P43243 | |
| Genevestigator | P43243 | |
| GO | GO:0016020 GO:0005637 GO:0016363 GO:0005634 GO:0000166 GO:0044822 GO:0005198 GO:0008270 | |
| Gene3D | 3.30.70.330 | |
| InterPro | IPR012677 IPR000504 IPR015880 IPR000690 IPR003604 | |
| SMART | SM00360 SM00355 SM00451 | |
| PROSITE | PS50102 PS50171 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0010608 |
posttranscriptional regulation of gene expression |
ECO:0000314 |
P |
Figure 1, 2 |
complete | |||||
| GO:0010608 |
posttranscriptional regulation of gene expression |
ECO:0000314 |
P |
Figure 3: western blot analysis of anti-HA antibodies shows interaction of Rev and Matrin 3 proteins (lane 8; upper panel) |
complete | |||||
|
acts_upstream_of_or_within |
GO:0003281 |
ventricular septum development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0003170 |
heart valve development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002218 |
activation of innate immune response |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0035198 |
miRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010608 |
posttranscriptional regulation of gene expression |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000504 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005637 |
nuclear inner membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005198 |
structural molecule activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045087 |
innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002376 |
immune system process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016363 |
nuclear matrix |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Yedavalli, VS & Jeang, KT (2011) Matrin 3 is a co-factor for HIV-1 Rev in regulating post-transcriptional viral gene expression. Retrovirology 8 61 PubMed GONUTS page
- ↑ Morchikh, M et al. (2017) HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response. Mol. Cell 67 387-399.e5 PubMed GONUTS page
- ↑ Treiber, T et al. (2017) A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis. Mol. Cell 66 270-284.e13 PubMed GONUTS page
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
- ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
- ↑ Rolland, T et al. (2014) A proteome-scale map of the human interactome network. Cell 159 1212-26 PubMed GONUTS page
- ↑ 8.0 8.1 Belgrader, P et al. (1991) Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain. J. Biol. Chem. 266 9893-9 PubMed GONUTS page
