HUMAN:ID2

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	ID2 (synonyms: BHLHB26)
Protein Name(s)	DNA-binding protein inhibitor ID-2 Class B basic helix-loop-helix protein 26 bHLHb26 Inhibitor of DNA binding 2 Inhibitor of differentiation 2
External Links
UniProt	Q02363
EMBL	D13891 M97796 BC030639
CCDS	CCDS1659.1
PIR	A40227 JC2007
RefSeq	NP_002157.2
UniGene	Hs.180919 Hs.726053
PDB	4AYA
PDBsum	4AYA
ProteinModelPortal	Q02363
SMR	Q02363
BioGrid	109624
DIP	DIP-46874N
IntAct	Q02363
MINT	MINT-1372728
STRING	9606.ENSP00000234091
PhosphoSite	Q02363
DMDM	729806
MaxQB	Q02363
PaxDb	Q02363
PRIDE	Q02363
DNASU	3398
Ensembl	ENST00000234091 ENST00000331129 ENST00000396290
GeneID	3398
KEGG	hsa:3398
UCSC	uc002qza.3
CTD	3398
GeneCards	GC02P008818
H-InvDB	HIX0204445
HGNC	HGNC:5361
HPA	HPA027612 HPA028681
MIM	600386
neXtProt	NX_Q02363
PharmGKB	PA29609
eggNOG	NOG76382
HOGENOM	HOG000234788
HOVERGEN	HBG009009
InParanoid	Q02363
KO	K17693
OMA	KNVSKME
OrthoDB	EOG7X9G8G
PhylomeDB	Q02363
TreeFam	TF326217
GeneWiki	ID2
GenomeRNAi	3398
NextBio	13428
PRO	PR:Q02363
Proteomes	UP000005640
Bgee	Q02363
CleanEx	HS_ID2
ExpressionAtlas	Q02363
Genevestigator	Q02363
GO	GO:0005813 GO:0000785 GO:0005737 GO:0005829 GO:0015630 GO:0005654 GO:0005634 GO:0043234 GO:0044325 GO:0060612 GO:0003166 GO:0048469 GO:0071285 GO:0090398 GO:0032922 GO:0048557 GO:0061031 GO:0043153 GO:0043353 GO:0061030 GO:0045475 GO:0060749 GO:0033598 GO:0003149 GO:0001656 GO:0007275 GO:0001779 GO:0045578 GO:0043392 GO:0010629 GO:2000178 GO:0045665 GO:0048715 GO:0045668 GO:0043433 GO:0000122 GO:0045892 GO:0048663 GO:0021772 GO:0014003 GO:0048541 GO:0048711 GO:0045777 GO:0071158 GO:0045648 GO:0045600 GO:0010628 GO:0045651 GO:0048661 GO:0071931 GO:0045893 GO:0042752 GO:2000045 GO:0019216 GO:0006351
Gene3D	4.10.280.10
InterPro	IPR011598 IPR026052
PANTHER	PTHR11723
Pfam	PF00010
SMART	SM00353
SUPFAM	SSF47459
PROSITE	PS50888

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[1]	ECO:0000303	author statement without traceable support used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[1]	ECO:0000255	match to sequence model evidence used in manual assertion	InterPro:IPR011598	F	Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0019216	regulation of lipid metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:20861012^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0045475	locomotor rhythm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0043153	entrainment of circadian clock by photoperiod	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:14627819^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	PMID:14627819^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:14627819^[3]	ECO:0000305	curator inference used in manual assertion	GO:0043433	C	Seeded From UniProt	complete
involved_in	GO:2000045	regulation of G1/S transition of mitotic cell cycle	PMID:16311606^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0071931	positive regulation of transcription involved in G1/S transition of mitotic cell cycle	PMID:16311606^[4]	ECO:0000305	curator inference used in manual assertion	GO:2000045	P	Seeded From UniProt	complete
enables	GO:0044325	ion channel binding	PMID:16311606^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q13563	F	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:16311606^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
colocalizes_with	GO:0005737	cytoplasm	PMID:16311606^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16311606^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:2000178	negative regulation of neural precursor cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0090398	cellular senescence	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0071158	positive regulation of cell cycle arrest	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0061031	endodermal digestive tract morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0060749	mammary gland alveolus development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0048663	neuron fate commitment	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0048661	positive regulation of smooth muscle cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0045777	positive regulation of blood pressure	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	C	Seeded From UniProt	complete
involved_in	GO:0033598	mammary gland epithelial cell proliferation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P41136	P	Seeded From UniProt	complete
involved_in	GO:0051726	regulation of cell cycle	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000919548 RGD:2860	P	Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96397 MGI:MGI:99414 PANTHER:PTN000919548 UniProtKB:O73933 UniProtKB:Q90X14 UniProtKB:Q90X15	P	Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000575 MGI:MGI:96396 MGI:MGI:96397 PANTHER:PTN000919548	P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000919548 RGD:2858 RGD:2859 RGD:2860	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96398 PANTHER:PTN000919548 RGD:2858	F	Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548	P	Seeded From UniProt	complete
colocalizes_with	GO:0005737	cytoplasm	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548 RGD:2859 UniProtKB:Q02363	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000575 MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548 RGD:2858 RGD:2859 RGD:2860 UniProtKB:O73933 UniProtKB:P47928 UniProtKB:Q02363	C	Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96398 PANTHER:PTN000919548	F	Seeded From UniProt	complete
enables	GO:0001085	RNA polymerase II transcription factor binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99414 PANTHER:PTN000919548	F	Seeded From UniProt	complete
involved_in	GO:2000178	negative regulation of neural precursor cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0090398	cellular senescence	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0071285	cellular response to lithium ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0071158	positive regulation of cell cycle arrest	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0061031	endodermal digestive tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0060749	mammary gland alveolus development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0060612	adipose tissue development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048715	negative regulation of oligodendrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048711	positive regulation of astrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048667	cell morphogenesis involved in neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048663	neuron fate commitment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048661	positive regulation of smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048557	embryonic digestive tract morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048541	Peyer's patch development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048469	cell maturation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0048468	cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045777	positive regulation of blood pressure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045668	negative regulation of osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045651	positive regulation of macrophage differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045648	positive regulation of erythrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045600	positive regulation of fat cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045578	negative regulation of B cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0045475	locomotor rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0043353	enucleate erythrocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0043153	entrainment of circadian clock by photoperiod	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0033598	mammary gland epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	C	Seeded From UniProt	complete
involved_in	GO:0032922	circadian regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0021772	olfactory bulb development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0019216	regulation of lipid metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0014003	oligodendrocyte development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0010629	negative regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0009649	entrainment of circadian clock	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0008344	adult locomotory behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	C	Seeded From UniProt	complete
involved_in	GO:0003166	bundle of His development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0003149	membranous septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0002521	leukocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0001966	thigmotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0001779	natural killer cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0001656	metanephros development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41136 ensembl:ENSMUSP00000152052	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	C	Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	P	Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011598 InterPro:IPR036638	F	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	PMID:1741406^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
↑ Ward, SM et al. (2010) The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression. J. Biol. Chem. 285 38987-9000 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Kim, HJ et al. (2003) Synergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1. Nucleic Acids Res. 31 6860-72 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Li, X et al. (2005) Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2. Nat. Cell Biol. 7 1202-12 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 ^5.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Biggs, J et al. (1992) A human Id-like helix-loop-helix protein expressed during early development. Proc. Natl. Acad. Sci. U.S.A. 89 1512-6 PubMed GONUTS page

[PMID:19274049-1] 1.0 ^1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page

[PMID:20861012-2] Ward, SM et al. (2010) The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression. J. Biol. Chem. 285 38987-9000 PubMed GONUTS page

[PMID:14627819-3] 3.0 ^3.1 ^3.2 Kim, HJ et al. (2003) Synergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1. Nucleic Acids Res. 31 6860-72 PubMed GONUTS page

[PMID:16311606-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Li, X et al. (2005) Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2. Nat. Cell Biol. 7 1202-12 PubMed GONUTS page

[PMID:21873635-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 ^5.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:1741406-6] Biggs, J et al. (1992) A human Id-like helix-loop-helix protein expressed during early development. Proc. Natl. Acad. Sci. U.S.A. 89 1512-6 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

HUMAN:ID2

Contents

Annotations

Notes

References

a

b

c

d

e

h

l

m

n

o

p

r

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools