HUMAN:CSF1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	CSF1
Protein Name(s)	Macrophage colony-stimulating factor 1 CSF-1 M-CSF MCSF Lanimostim Processed macrophage colony-stimulating factor 1
External Links
UniProt	P09603
EMBL	M11296 M11038 M11295 M37435 M64592 U22386 M27087 AK291660 AL450468 AL450468 CH471122 BC021117 X05825 X06106 M76453
CCDS	CCDS30797.1 CCDS816.1 CCDS817.1
PIR	A47583
RefSeq	NP_000748.3 NP_757349.1 NP_757350.1 NP_757351.1
UniGene	Hs.173894
PDB	1HMC 3UEZ 3UF2 4ADF 4FA8
PDBsum	1HMC 3UEZ 3UF2 4ADF 4FA8
ProteinModelPortal	P09603
SMR	P09603
BioGrid	107822
DIP	DIP-41860N
IntAct	P09603
MINT	MINT-196477
STRING	9606.ENSP00000327513
PhosphoSite	P09603
DMDM	311033367
MaxQB	P09603
PaxDb	P09603
PRIDE	P09603
DNASU	1435
Ensembl	ENST00000329608 ENST00000369801 ENST00000369802 ENST00000420111
GeneID	1435
KEGG	hsa:1435
UCSC	uc001dyt.2 uc001dyu.2 uc021orj.2
CTD	1435
GeneCards	GC01P110453
HGNC	HGNC:2432
MIM	120420
neXtProt	NX_P09603
PharmGKB	PA26935
eggNOG	NOG43822
GeneTree	ENSGT00390000015805
HOVERGEN	HBG005410
InParanoid	P09603
KO	K05453
OMA	DTGHERQ
OrthoDB	EOG7GBFZ6
PhylomeDB	P09603
TreeFam	TF337718
SignaLink	P09603
ChiTaRS	CSF1
EvolutionaryTrace	P09603
GeneWiki	Macrophage_colony-stimulating_factor
GenomeRNAi	1435
NextBio	5857
PMAP-CutDB	P09603
PRO	PR:P09603
Proteomes	UP000005640
Bgee	P09603
CleanEx	HS_CSF1
ExpressionAtlas	P09603
Genevestigator	P09603
GO	GO:0005615 GO:0070062 GO:0016021 GO:0016020 GO:0048471 GO:0005886 GO:0043235 GO:0005125 GO:0008083 GO:0005157 GO:0042803 GO:0060444 GO:0030154 GO:0008283 GO:0003006 GO:0030097 GO:0048873 GO:0006954 GO:0045087 GO:0030225 GO:0060763 GO:0060611 GO:0042117 GO:0042476 GO:0001503 GO:0030316 GO:0002158 GO:0030335 GO:0008284 GO:0001954 GO:0032270 GO:0010628 GO:0010744 GO:0045651 GO:0045657 GO:0032946 GO:0040018 GO:0042488 GO:0045672 GO:0045860 GO:0046579 GO:0010743 GO:0030278
InterPro	IPR009079 IPR008001
PANTHER	PTHR10058
Pfam	PF05337
PIRSF	PIRSF001948
SUPFAM	SSF47266

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0002931	response to ischemia	PMID:8922060^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0000956)	Seeded From UniProt	complete
involved_in	GO:1901215	negative regulation of neuron death	PMID:8922060^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(UBERON:0000956) regulates_o_occurs_in:(UBERON:0000956) part_of:(GO:0002931)	Seeded From UniProt	complete
involved_in	GO:1902228	positive regulation of macrophage colony-stimulating factor signaling pathway	PMID:19100238^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	PMID:19100238^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010759	positive regulation of macrophage chemotaxis	PMID:19100238^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1904141	positive regulation of microglial cell migration	PMID:19100238^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	PMID:1739124^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0045860	positive regulation of protein kinase activity	PMID:18566389^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	P		Seeded From UniProt	complete
involved_in	GO:0045672	positive regulation of osteoclast differentiation	PMID:15304486^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045657	positive regulation of monocyte differentiation	PMID:18566389^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	P		Seeded From UniProt	complete
involved_in	GO:0045651	positive regulation of macrophage differentiation	PMID:2460758^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:1990682	CSF1-CSF1R complex	PMID:19017797^[7]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	C		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:3264878^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042117	monocyte activation	PMID:18566389^[4]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032946	positive regulation of mononuclear cell proliferation	PMID:2460758^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032270	positive regulation of cellular protein metabolic process	PMID:1739124^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	PMID:18566389^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	P		Seeded From UniProt	complete
involved_in	GO:0030316	osteoclast differentiation	PMID:18606301^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010744	positive regulation of macrophage derived foam cell differentiation	PMID:17244792^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010743	regulation of macrophage derived foam cell differentiation	PMID:18566389^[4]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:1739124^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	PMID:10666185^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	PMID:2460758^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:2460758^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005157	macrophage colony-stimulating factor receptor binding	PMID:19017797^[7]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	F		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	PMID:2460758^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0003006	developmental process involved in reproduction	PMID:19017797^[7]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	P		Seeded From UniProt	complete
involved_in	GO:0001954	positive regulation of cell-matrix adhesion	PMID:18566389^[4]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07141	P		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	PMID:1791839^[12]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030097	hemopoiesis	PMID:1791839^[12]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:2460758^[6]	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0008283	cell population proliferation	PMID:1791839^[12]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	PMID:1791839^[12]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0045651	positive regulation of macrophage differentiation	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1339753 PANTHER:PTN001296023 UniProtKB:P09603	P		Seeded From UniProt	complete
involved_in	GO:0030316	osteoclast differentiation	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1339753 PANTHER:PTN001296023 RGD:621063 UniProtKB:P09603	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002559881 RGD:621063 UniProtKB:P09603	C		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002559881 UniProtKB:P09603	F		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	PMID:10652277^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	PMID:10652277^[14]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:22902366^[15]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P09603	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:22153499^[16]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P09603	F		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005125	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005125	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005125	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
part_of	GO:1990682	CSF1-CSF1R complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	C		Seeded From UniProt	complete
involved_in	GO:0061518	microglial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0060763	mammary duct terminal end bud growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0060611	mammary gland fat development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0060444	branching involved in mammary gland duct morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0048873	homeostasis of number of cells within a tissue	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0046579	positive regulation of Ras protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0045860	positive regulation of protein kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0045672	positive regulation of osteoclast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0045657	positive regulation of monocyte differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0045651	positive regulation of macrophage differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	F		Seeded From UniProt	complete
involved_in	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0040018	positive regulation of multicellular organism growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0038145	macrophage colony-stimulating factor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0030316	osteoclast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0030278	regulation of ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
enables	GO:0005157	macrophage colony-stimulating factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	F		Seeded From UniProt	complete
involved_in	GO:0003006	developmental process involved in reproduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0002158	osteoclast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
involved_in	GO:0001954	positive regulation of cell-matrix adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P07141 ensembl:ENSMUSP00000014743	P		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008001	F		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008001	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008001	C		Seeded From UniProt	complete
involved_in	GO:0030225	macrophage differentiation	PMID:2460758^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	PMID:2460758^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005157	macrophage colony-stimulating factor receptor binding	PMID:2460758^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0044267	cellular protein metabolic process	Reactome:R-HSA-392499	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043687	post-translational protein modification	Reactome:R-HSA-597592	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	Reactome:R-HSA-6783783 Reactome:R-HSA-449836	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-8937656	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005788	endoplasmic reticulum lumen	Reactome:R-HSA-8952289	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-HSA-9009488 Reactome:R-HSA-9009485	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0391	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0395	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202 UniProtKB-SubCell:SL-0112	C		Seeded From UniProt	complete
involved_in	GO:0045087	innate immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0399	P		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Berezovskaya, O et al. (1996) Colony stimulating factor-1 potentiates neuronal survival in cerebral cortex ischemic lesion. Acta Neuropathol. 92 479-86 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Stoecker, K et al. (2009) Induction of STAP-1 promotes neurotoxic activation of microglia. Biochem. Biophys. Res. Commun. 379 121-6 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Clinton, SK et al. (1992) Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis. Am. J. Pathol. 140 301-16 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Bonfield, TL et al. (2008) Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor. J. Immunol. 181 235-42 PubMed GONUTS page
↑ Matsumoto, M et al. (2004) Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1. J. Biol. Chem. 279 45969-79 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 ^6.8 Cerretti, DP et al. (1988) Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene. Mol. Immunol. 25 761-70 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Chen, X et al. (2008) Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases. Proc. Natl. Acad. Sci. U.S.A. 105 18267-72 PubMed GONUTS page
↑ Manos, MM (1988) Expression and processing of a recombinant human macrophage colony-stimulating factor in mouse cells. Mol. Cell. Biol. 8 5035-9 PubMed GONUTS page
↑ Guerrini, MM et al. (2008) Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am. J. Hum. Genet. 83 64-76 PubMed GONUTS page
↑ Cho, HJ et al. (2007) Induction of dendritic cell-like phenotype in macrophages during foam cell formation. Physiol. Genomics 29 149-60 PubMed GONUTS page
↑ Scheuerer, B et al. (2000) The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages. Blood 95 1158-66 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 ^12.3 Pampfer, S et al. (1991) Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1. Mol. Endocrinol. 5 1931-8 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 ^13.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^14.0 ^14.1 Kieslinger, M et al. (2000) Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Genes Dev. 14 232-44 PubMed GONUTS page
↑ Elegheert, J et al. (2012) Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1. Nat. Struct. Mol. Biol. 19 938-47 PubMed GONUTS page
↑ Elegheert, J et al. (2011) Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles. Structure 19 1762-72 PubMed GONUTS page

[PMID:8922060-1] 1.0 ^1.1 Berezovskaya, O et al. (1996) Colony stimulating factor-1 potentiates neuronal survival in cerebral cortex ischemic lesion. Acta Neuropathol. 92 479-86 PubMed GONUTS page

[PMID:19100238-2] 2.0 ^2.1 ^2.2 ^2.3 Stoecker, K et al. (2009) Induction of STAP-1 promotes neurotoxic activation of microglia. Biochem. Biophys. Res. Commun. 379 121-6 PubMed GONUTS page

[PMID:1739124-3] 3.0 ^3.1 ^3.2 Clinton, SK et al. (1992) Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis. Am. J. Pathol. 140 301-16 PubMed GONUTS page

[PMID:18566389-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Bonfield, TL et al. (2008) Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor. J. Immunol. 181 235-42 PubMed GONUTS page

[PMID:15304486-5] Matsumoto, M et al. (2004) Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1. J. Biol. Chem. 279 45969-79 PubMed GONUTS page

[PMID:2460758-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 ^6.8 Cerretti, DP et al. (1988) Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene. Mol. Immunol. 25 761-70 PubMed GONUTS page

[PMID:19017797-7] 7.0 ^7.1 ^7.2 Chen, X et al. (2008) Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases. Proc. Natl. Acad. Sci. U.S.A. 105 18267-72 PubMed GONUTS page

[PMID:3264878-8] Manos, MM (1988) Expression and processing of a recombinant human macrophage colony-stimulating factor in mouse cells. Mol. Cell. Biol. 8 5035-9 PubMed GONUTS page

[PMID:18606301-9] Guerrini, MM et al. (2008) Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am. J. Hum. Genet. 83 64-76 PubMed GONUTS page

[PMID:17244792-10] Cho, HJ et al. (2007) Induction of dendritic cell-like phenotype in macrophages during foam cell formation. Physiol. Genomics 29 149-60 PubMed GONUTS page

[PMID:10666185-11] Scheuerer, B et al. (2000) The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages. Blood 95 1158-66 PubMed GONUTS page

[PMID:1791839-12] 12.0 ^12.1 ^12.2 ^12.3 Pampfer, S et al. (1991) Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1. Mol. Endocrinol. 5 1931-8 PubMed GONUTS page

[PMID:21873635-13] 13.0 ^13.1 ^13.2 ^13.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10652277-14] 14.0 ^14.1 Kieslinger, M et al. (2000) Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Genes Dev. 14 232-44 PubMed GONUTS page

[PMID:22902366-15] Elegheert, J et al. (2012) Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1. Nat. Struct. Mol. Biol. 19 938-47 PubMed GONUTS page

[PMID:22153499-16] Elegheert, J et al. (2011) Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles. Structure 19 1762-72 PubMed GONUTS page

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