GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
HUMAN:CCKN
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | CCK | |
Protein Name(s) | Cholecystokinin
CCK Cholecystokinin-58 CCK58 Cholecystokinin-58 desnonopeptide (1-49)-CCK58 Cholecystokinin-39 CCK39 Cholecystokinin-33 CCK33 Cholecystokinin-25 CCK25 Cholecystokinin-18 CCK18 Cholecystokinin-12 CCK12 Cholecystokinin-8 CCK8 Cholecystokinin-7 CCK7 Cholecystokinin-5 CCK5 | |
External Links | ||
UniProt | P06307 | |
EMBL | L00354 BT006991 AY514491 BC008283 | |
CCDS | CCDS2696.1 | |
PIR | A01623 | |
RefSeq | NP_000720.1 NP_001167609.1 | |
UniGene | Hs.458426 | |
ProteinModelPortal | P06307 | |
BioGrid | 107327 | |
IntAct | P06307 | |
STRING | 9606.ENSP00000335657 | |
BindingDB | P06307 | |
ChEMBL | CHEMBL1649050 | |
PhosphoSite | P06307 | |
DMDM | 115945 | |
PaxDb | P06307 | |
PRIDE | P06307 | |
DNASU | 885 | |
Ensembl | ENST00000334681 ENST00000396169 ENST00000434608 | |
GeneID | 885 | |
KEGG | hsa:885 | |
UCSC | uc003cld.1 | |
CTD | 885 | |
GeneCards | GC03M042274 | |
HGNC | HGNC:1569 | |
HPA | CAB002308 | |
MIM | 118440 | |
neXtProt | NX_P06307 | |
PharmGKB | PA26141 | |
eggNOG | NOG40485 | |
HOGENOM | HOG000073533 | |
HOVERGEN | HBG005806 | |
InParanoid | P06307 | |
KO | K05226 | |
OMA | GRMSIVK | |
OrthoDB | EOG7F7WBS | |
PhylomeDB | P06307 | |
TreeFam | TF333419 | |
Reactome | REACT_14819 REACT_18283 | |
ChiTaRS | CCK | |
GeneWiki | Cholecystokinin | |
GenomeRNAi | 885 | |
NextBio | 3658 | |
PMAP-CutDB | P06307 | |
PRO | PR:P06307 | |
Proteomes | UP000005640 | |
Bgee | P06307 | |
CleanEx | HS_CCK | |
ExpressionAtlas | P06307 | |
Genevestigator | P06307 | |
GO | GO:0030424 GO:0043203 GO:0043194 GO:0030425 GO:0005576 GO:0005615 GO:0043204 GO:0043195 GO:0005179 GO:0005184 GO:0006919 GO:0007409 GO:0001662 GO:0042755 GO:0032099 GO:0001764 GO:0008284 GO:0051901 GO:0050731 GO:0032461 GO:0007205 GO:0051930 GO:0001836 GO:0007165 | |
InterPro | IPR015499 IPR001651 IPR013152 | |
PANTHER | PTHR10786 | |
Pfam | PF00918 | |
SMART | SM00029 | |
PROSITE | PS00259 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0051428 |
peptide hormone receptor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042755 |
eating behavior |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0030424 |
axon |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007409 |
axonogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001764 |
neuron migration |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0030424 |
axon |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88297 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007586 |
digestion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002583982 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002583982 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88297 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005179 |
hormone activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002583982 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2000987 |
positive regulation of behavioral fear response |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2000986 |
negative regulation of behavioral fear response |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1904058 |
positive regulation of sensory perception of pain |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903999 |
negative regulation of eating behavior |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051930 |
regulation of sensory perception of pain |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051901 |
positive regulation of mitochondrial depolarization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043204 |
perikaryon |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043203 |
axon hillock |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043195 |
terminal bouton |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043194 |
axon initial segment |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043065 |
positive regulation of apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042755 |
eating behavior |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032461 |
positive regulation of protein oligomerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032099 |
negative regulation of appetite |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0030425 |
dendrite |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0014049 |
positive regulation of glutamate secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008542 |
visual learning |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007613 |
memory |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007205 |
protein kinase C-activating G protein-coupled receptor signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006919 |
activation of cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005179 |
hormone activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001836 |
release of cytochrome c from mitochondria |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P01355 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042755 |
eating behavior |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09240 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0030424 |
axon |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09240 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007409 |
axonogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09240 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09240 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001764 |
neuron migration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09240 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005179 |
hormone activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007165 |
signal transduction |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005179 |
hormone activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
Reactome:R-HSA-388396 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-749452 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
enables |
GO:0005179 |
hormone activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lee, YM et al. (1993) The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization. J. Biol. Chem. 268 8164-9 PubMed GONUTS page
- ↑ 2.0 2.1 Hnasko, TS et al. (2004) A role for dopamine in feeding responses produced by orexigenic agents. Brain Res. 1023 309-18 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Giacobini, P et al. (2004) Cholecystokinin modulates migration of gonadotropin-releasing hormone-1 neurons. J. Neurosci. 24 4737-48 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 5.0 5.1 Anders, J et al. (1999) Direct identification of the agonist binding site in the human brain cholecystokininB receptor. Biochemistry 38 6043-55 PubMed GONUTS page
a
e
n
o
p
- GO:0051428 ! peptide hormone receptor binding
- GO:0043204 ! perikaryon
- GO:0050731 ! positive regulation of peptidyl-tyrosine phosphorylation
- GO:2000987 ! positive regulation of behavioral fear response
- GO:1904058 ! positive regulation of sensory perception of pain
- GO:0051901 ! positive regulation of mitochondrial depolarization
- GO:0014049 ! positive regulation of glutamate secretion
- GO:0043065 ! positive regulation of apoptotic process
- GO:0032461 ! positive regulation of protein oligomerization
- GO:0008284 ! positive regulation of cell population proliferation
- Primates
r