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DROME:SING
Contents
Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
Gene Name(s) | sn | |
Protein Name(s) | Protein singed | |
External Links | ||
UniProt | Q24524 | |
EMBL | X17549 X17550 AE014298 | |
RefSeq | NP_001162697.1 NP_511076.3 NP_727226.1 NP_727227.1 | |
UniGene | Dm.7274 | |
ProteinModelPortal | Q24524 | |
SMR | Q24524 | |
BioGrid | 58189 | |
MINT | MINT-295848 | |
STRING | 7227.FBpp0071056 | |
PaxDb | Q24524 | |
PRIDE | Q24524 | |
EnsemblMetazoa | FBtr0071101 FBtr0071102 FBtr0301676 FBtr0301677 FBtr0301678 FBtr0301679 | |
GeneID | 31717 | |
KEGG | dme:Dmel_CG32858 | |
UCSC | CG32858-RA | |
CTD | 31717 | |
FlyBase | FBgn0003447 | |
eggNOG | NOG85029 | |
GeneTree | ENSGT00530000063373 | |
InParanoid | Q24524 | |
KO | K17455 | |
OMA | HRWALRT | |
OrthoDB | EOG761BV4 | |
PhylomeDB | Q24524 | |
GenomeRNAi | 31717 | |
NextBio | 774985 | |
PRO | PR:Q24524 | |
Proteomes | UP000000803 | |
Bgee | Q24524 | |
ExpressionAtlas | Q24524 | |
GO | GO:0015629 GO:0005737 GO:0043005 GO:0043025 GO:0003779 GO:0051015 GO:0030036 GO:0051017 GO:0007015 GO:0048800 GO:0008407 GO:0035017 GO:0016358 GO:0009913 GO:0007163 GO:0046847 GO:0035099 GO:0035317 GO:0030034 GO:0048812 GO:0048477 GO:0042060 | |
InterPro | IPR008999 IPR010431 IPR022768 IPR024703 | |
PANTHER | PTHR10551 | |
Pfam | PF06268 | |
PIRSF | PIRSF005682 | |
SUPFAM | SSF50405 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
Colocalizes with |
GO:0034399 |
nuclear periphery |
ECO:0000314 |
C |
Figure 1: Live imaging of late stage follicles reveals GFP-Fascin, is in the nucleus during S10B-S12 (F-H) and at the nuclear periphery during S13 (I, J). |
complete | ||||
colocalizes_with |
GO:0034399 |
nuclear periphery |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0051015 |
actin filament binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003779 |
actin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051017 |
actin filament bundle assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003447 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0051015 |
actin filament binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1352745 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0016477 |
cell migration |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1352745 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007163 |
establishment or maintenance of cell polarity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003447 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003447 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0043005 |
neuron projection |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016358 |
dendrite development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046847 |
filopodium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051017 |
actin filament bundle assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042060 |
wound healing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007163 |
establishment or maintenance of cell polarity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0015629 |
actin cytoskeleton |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035099 |
hemocyte migration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030036 |
actin cytoskeleton organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048812 |
neuron projection morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0009913 |
epidermal cell differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035017 |
cuticle pattern formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051017 |
actin filament bundle assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035317 |
imaginal disc-derived wing hair organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030034 |
microvillar actin bundle assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051017 |
actin filament bundle assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008407 |
chaeta morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048800 |
antennal morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003779 |
actin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
Missing: with/from | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007015 |
actin filament organization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0030674 |
protein binding, bridging |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051015 |
actin filament binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007015 |
actin filament organization |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048477 |
oogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Groen, CM et al. (2015) Prostaglandins regulate nuclear localization of Fascin and its function in nucleolar architecture. Mol. Biol. Cell 26 1901-17 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Nagel, J et al. (2012) Fascin controls neuronal class-specific dendrite arbor morphology. Development 139 2999-3009 PubMed GONUTS page
- ↑ 4.0 4.1 Zanet, J et al. (2012) Fascin promotes filopodia formation independent of its role in actin bundling. J. Cell Biol. 197 477-86 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Zanet, J et al. (2009) Fascin is required for blood cell migration during Drosophila embryogenesis. Development 136 2557-65 PubMed GONUTS page
- ↑ Kraft, R et al. (2006) Phenotypes of Drosophila brain neurons in primary culture reveal a role for fascin in neurite shape and trajectory. J. Neurosci. 26 8734-47 PubMed GONUTS page
- ↑ 7.0 7.1 Chanut-Delalande, H et al. (2006) Shavenbaby couples patterning to epidermal cell shape control. PLoS Biol. 4 e290 PubMed GONUTS page
- ↑ 8.0 8.1 Guild, GM et al. (2005) Actin filament bundles in Drosophila wing hairs: hairs and bristles use different strategies for assembly. Mol. Biol. Cell 16 3620-31 PubMed GONUTS page
- ↑ Tilney, LG et al. (2004) Microvilli appear to represent the first step in actin bundle formation in Drosophila bristles. J. Cell. Sci. 117 3531-8 PubMed GONUTS page
- ↑ Tilney, LG et al. (2003) Actin filament turnover regulated by cross-linking accounts for the size, shape, location, and number of actin bundles in Drosophila bristles. Mol. Biol. Cell 14 3953-66 PubMed GONUTS page
- ↑ Guild, GM et al. (2003) Long continuous actin bundles in Drosophila bristles are constructed by overlapping short filaments. J. Cell Biol. 162 1069-77 PubMed GONUTS page
- ↑ He, B & Adler, PN (2002) The genetic control of arista lateral morphogenesis in Drosophila. Dev. Genes Evol. 212 218-29 PubMed GONUTS page
- ↑ Goldstein, LS & Gunawardena, S (2000) Flying through the drosophila cytoskeletal genome. J. Cell Biol. 150 F63-8 PubMed GONUTS page
- ↑ Cant, K et al. (1994) Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension. J. Cell Biol. 125 369-80 PubMed GONUTS page
- ↑ Buszczak, M & Cooley, L (2000) Eggs to die for: cell death during Drosophila oogenesis. Cell Death Differ. 7 1071-4 PubMed GONUTS page
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