DROME:Q9V3I2

Species (Taxon ID)	Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s)	No Information Provided. (synonyms: Drab5 (ECO:0000313 with EMBL:BAA87879.1))
Protein Name(s)	Drab5 (ECO:0000313 with EMBL:BAA87879.1) Rab5 (ECO:0000313 with EMBL:AAN85552.1) Rab5 protein (ECO:0000313 with EMBL:BAA88244.1) Rab5, isoform A (ECO:0000313 with EMBL:AAF51265.1) Rab5, isoform B (ECO:0000313 with EMBL:AAN10422.1) Rab5, isoform C (ECO:0000313 with EMBL:AAN10423.1) Rab5, isoform D (ECO:0000313 with EMBL:AAN10424.1) Rab5, isoform G (ECO:0000313 with EMBL:AGB92462.1) Rab5, isoform H (ECO:0000313 with EMBL:AGB92463.1) Rab5, isoform I (ECO:0000313 with EMBL:AGB92464.1)
External Links
UniProt	Q9V3I2
EMBL	AE014134 AY060343 AE014134 AE014134 AE014134 AE014134 AE014134 AY081180 AY081181 AE014134 AE014134 AE014134 AB035353 AB035671 BK000968
RefSeq	NP_001259925.1 NP_001259926.1 NP_001259927.1 NP_523457.1 NP_722795.1 NP_722796.1 NP_722797.1 NP_722798.1 NP_722799.1
UniGene	Dm.6724
MINT	MINT-334912
STRING	7227.FBpp0077473
EnsemblMetazoa	[example_ID FBtr0077793] [example_ID FBtr0077794] [example_ID FBtr0077795] [example_ID FBtr0077796] [example_ID FBtr0077797] [example_ID FBtr0077798] [example_ID FBtr0330668] [example_ID FBtr0330669] [example_ID FBtr0330670]
GeneID	33418
KEGG	dme:Dmel_CG3664
UCSC	CG3664-RA
CTD	33418
FlyBase	FBgn0014010
eggNOG	KOG0092 ENOG410YCCP
GeneTree	ENSGT00760000119101
KO	K07889
OMA	GASFFRY
OrthoDB	EOG77DJ7M
Reactome	R-DME-983231
GenomeRNAi	33418
NextBio	783450
Proteomes	UP000000803
GO	GO:0005769 GO:0030139 GO:0005811 GO:0043025 GO:0005886 GO:0045202 GO:0031982 GO:0005525 GO:0003924 GO:0048675 GO:0007409 GO:0007298 GO:0007349 GO:0006325 GO:0048813 GO:0046664 GO:0006897 GO:0034058 GO:0060429 GO:0035088 GO:0016321 GO:0007293 GO:0016348 GO:0048803 GO:0007067 GO:0008285 GO:0007220 GO:0048477 GO:0048227 GO:0015031 GO:0032482 GO:0030100 GO:0010906 GO:0050803 GO:0048488 GO:0016189 GO:0016192 GO:0035220
Gene3D	3.40.50.300
InterPro	IPR027417 IPR005225 IPR001806 IPR003579
Pfam	PF00071
SMART	SM00175
SUPFAM	SSF52540
TIGRFAMs	TIGR00231

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005769	early endosome	PMID:27064279^[1]	ECO:0000314			C		Figure 3. showed that full-length APP and C99, but not C83, induced the enlargement of Rab5+ early endosomes in PC12M cells.	complete CACAO 11742
involved_in	GO:0034058	endosomal vesicle fusion	PMID:27253064^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0099532	synaptic vesicle endosomal processing	PMID:12743108^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(GO:0031594)	Seeded From UniProt	complete
involved_in	GO:0048488	synaptic vesicle endocytosis	PMID:20956291^[4]	ECO:0006063	over expression analysis evidence used in manual assertion		P	occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0048488	synaptic vesicle endocytosis	PMID:20956291^[4]	ECO:0005589	confocal microscopy evidence used in manual assertion		P	occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0032482	Rab protein signal transduction	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015790 PANTHER:PTN001292747 RGD:3529 dictyBase:DDB_G0269238	P		Seeded From UniProt	complete
part_of	GO:0030139	endocytic vesicle	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105306 MGI:MGI:105926 MGI:MGI:105938 PANTHER:PTN000634566 UniProtKB:Q9H0T7	C		Seeded From UniProt	complete
involved_in	GO:0030100	regulation of endocytosis	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0014010 MGI:MGI:105306 MGI:MGI:105938 PANTHER:PTN001179601	P		Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0014010 PANTHER:PTN000634659 UniProtKB:Q9NX57 WB:WBGene00004268	P		Seeded From UniProt	complete
involved_in	GO:0006886	intracellular protein transport	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1914292 PANTHER:PTN001292747 TAIR:locus:2094029 TAIR:locus:2123010 UniProtKB:Q9BW83	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105926 PANTHER:PTN000634601 RGD:620936	C		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0014010 MGI:MGI:105926 PANTHER:PTN000634601 RGD:620936 UniProtKB:P20339 UniProtKB:Q5B3G5 WB:WBGene00004268	C		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0014010 MGI:MGI:104640 MGI:MGI:105926 PANTHER:PTN000634601 RGD:620936 UniProtKB:P20339 UniProtKB:Q5B3G5 WB:WBGene00004268	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105926 PANTHER:PTN000634566 RGD:620936 TAIR:locus:2123010 UniProtKB:O96193 UniProtKB:P51148 UniProtKB:P61020 WB:WBGene00004268	C		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0015790 FB:FBgn0015797 FB:FBgn0016700 MGI:MGI:104606 MGI:MGI:105072 MGI:MGI:105926 MGI:MGI:1861441 MGI:MGI:1931295 MGI:MGI:2443036 MGI:MGI:99425 PANTHER:PTN001292747 PomBase:SPAC1565.06c PomBase:SPAC4C5.02c PomBase:SPBC1703.10 RGD:3529 RGD:619762 SGD:S000000833 SGD:S000001722 SGD:S000001856 SGD:S000001889 SGD:S000003178 SGD:S000004252 SGD:S000004460 SGD:S000004529 SGD:S000005037 SGD:S000005615 TAIR:locus:2041036 TAIR:locus:2082672 TAIR:locus:2202280 TAIR:locus:505006713 UniProtKB:P20336 UniProtKB:P20337 UniProtKB:P20338 UniProtKB:P20339 UniProtKB:P20340 UniProtKB:P51148 UniProtKB:P51149 UniProtKB:P51151 UniProtKB:P61006 UniProtKB:P61019 UniProtKB:P61020 UniProtKB:P61106 UniProtKB:P62491 UniProtKB:P62820 UniProtKB:Q13637 UniProtKB:Q14088 UniProtKB:Q15286 UniProtKB:Q15907 UniProtKB:Q86YS6 UniProtKB:Q96E17 UniProtKB:Q9H082 UniProtKB:Q9H0N0 UniProtKB:Q9H0T7 UniProtKB:Q9UL25 UniProtKB:Q9UL26 UniProtKB:Q9ULC3 WB:WBGene00004268 WB:WBGene00004271 WB:WBGene00006833	F		Seeded From UniProt	complete
part_of	GO:0005938	cell cortex	PMID:26265702^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0032509	endosome transport via multivesicular body sorting pathway	PMID:28420712^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048488	synaptic vesicle endocytosis	PMID:28482024^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	FB:FBgn0034708	P		Seeded From UniProt	complete
involved_in	GO:0048675	axon extension	PMID:25312435^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:19317464^[10]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007298	border follicle cell migration	PMID:22825871^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:22648168^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:22000105^[13]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	PMID:22000105^[13]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0048803	imaginal disc-derived male genitalia morphogenesis	PMID:21729695^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0046664	dorsal closure, amnioserosa morphology change	PMID:21533196^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007298	border follicle cell migration	PMID:21149700^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048813	dendrite morphogenesis	PMID:18758452^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007409	axonogenesis	PMID:18758452^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034058	endosomal vesicle fusion	PMID:18685079^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:18685079^[18]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0048227	plasma membrane to endosome transport	PMID:18685079^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030100	regulation of endocytosis	PMID:19050045^[19]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048477	oogenesis	PMID:19050045^[19]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035220	wing disc development	PMID:19000840^[20]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:19000840^[20]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007220	Notch receptor processing	PMID:19000840^[20]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	FB:FBgn0015790	F		Seeded From UniProt	complete
involved_in	GO:0032482	Rab protein signal transduction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	FB:FBgn0015790	P		Seeded From UniProt	complete
part_of	GO:0031982	vesicle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	FB:FBgn0015790	C		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	FB:FBgn0015790	P		Seeded From UniProt	complete
involved_in	GO:0035088	establishment or maintenance of apical/basal cell polarity	PMID:16258546^[21]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	PMID:16258546^[21]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007298	border follicle cell migration	PMID:16014514^[22]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:16014514^[22]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007298	border follicle cell migration	PMID:15944190^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:16137758^[24]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:14579253^[25]	ECO:0000250	sequence similarity evidence used in manual assertion		F		Seeded From UniProt	Missing: with/from
involved_in	GO:0007349	cellularization	PMID:14588240^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050803	regulation of synapse structure or activity	PMID:12876219^[27]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016189	synaptic vesicle to endosome fusion	PMID:12743108^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000278	mitotic cell cycle	PMID:11290718^[28]	ECO:0007001	high throughput mutant phenotypic evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016321	female meiosis chromosome segregation	PMID:11290718^[28]	ECO:0007001	high throughput mutant phenotypic evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006325	chromatin organization	PMID:11290718^[28]	ECO:0007001	high throughput mutant phenotypic evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:11136982^[29]	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0061883	clathrin-dependent endocytosis involved in vitellogenesis	PMID:26265702^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048488	C		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048488	C		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048488	C		Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048488	C		Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806	F		Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806 InterPro:IPR005225	F		Seeded From UniProt	complete
involved_in	GO:0016189	synaptic vesicle to endosome fusion	PMID:11136982^[29]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048488	synaptic vesicle endocytosis	PMID:11136982^[29]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Xu, W et al. (2016) Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration. J. Clin. Invest. PubMed GONUTS page
↑ Lőrincz, P et al. (2016) MiniCORVET is a Vps8-containing early endosomal tether in Drosophila. Elife 5 PubMed GONUTS page
↑ ^3.0 ^3.1 Wucherpfennig, T et al. (2003) Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J. Cell Biol. 161 609-24 PubMed GONUTS page
↑ ^4.0 ^4.1 Hoopmann, P et al. (2010) Endosomal sorting of readily releasable synaptic vesicles. Proc. Natl. Acad. Sci. U.S.A. 107 19055-60 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 ^5.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^6.0 ^6.1 Liu, G et al. (2015) Efficient Endocytic Uptake and Maturation in Drosophila Oocytes Requires Dynamitin/p50. Genetics 201 631-49 PubMed GONUTS page
↑ Wang, Y et al. (2017) Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of sensory neurons. Development 144 1851-1862 PubMed GONUTS page
↑ Inoshita, T et al. (2017) Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila. Hum. Mol. Genet. 26 2933-2948 PubMed GONUTS page
↑ Sakuma, C et al. (2014) Drosophila Strip serves as a platform for early endosome organization during axon elongation. Nat Commun 5 5180 PubMed GONUTS page
↑ Tan, DJ et al. (2009) Mapping organelle proteins and protein complexes in Drosophila melanogaster. J. Proteome Res. 8 2667-78 PubMed GONUTS page
↑ Chen, DY et al. (2012) The Bro1-domain-containing protein Myopic/HDPTP coordinates with Rab4 to regulate cell adhesion and migration. J. Cell. Sci. 125 4841-52 PubMed GONUTS page
↑ Jean, S et al. (2012) Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. Mol. Biol. Cell 23 2723-40 PubMed GONUTS page
↑ ^13.0 ^13.1 Chan, CC et al. (2011) Systematic discovery of Rab GTPases with synaptic functions in Drosophila. Curr. Biol. 21 1704-15 PubMed GONUTS page
↑ Lee, G et al. (2011) UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. Dev. Biol. 356 588-97 PubMed GONUTS page
↑ Mateus, AM et al. (2011) Endocytic and recycling endosomes modulate cell shape changes and tissue behaviour during morphogenesis in Drosophila. PLoS ONE 6 e18729 PubMed GONUTS page
↑ Assaker, G et al. (2010) Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. Proc. Natl. Acad. Sci. U.S.A. 107 22558-63 PubMed GONUTS page
↑ ^17.0 ^17.1 Satoh, D et al. (2008) Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat. Cell Biol. 10 1164-71 PubMed GONUTS page
↑ ^18.0 ^18.1 ^18.2 Morrison, HA et al. (2008) Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45. Mol. Biol. Cell 19 4167-76 PubMed GONUTS page
↑ ^19.0 ^19.1 Compagnon, J et al. (2009) Interplay between Rab5 and PtdIns(4,5)P2 controls early endocytosis in the Drosophila germline. J. Cell. Sci. 122 25-35 PubMed GONUTS page
↑ ^20.0 ^20.1 ^20.2 Wilkin, M et al. (2008) Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway. Dev. Cell 15 762-72 PubMed GONUTS page
↑ ^21.0 ^21.1 Lu, H & Bilder, D (2005) Endocytic control of epithelial polarity and proliferation in Drosophila. Nat. Cell Biol. 7 1232-9 PubMed GONUTS page
↑ ^22.0 ^22.1 Schober, M et al. (2005) Function of the ETS transcription factor Yan in border cell migration. Development 132 3493-504 PubMed GONUTS page
↑ Medioni, C & Noselli, S (2005) Dynamics of the basement membrane in invasive epithelial clusters in Drosophila. Development 132 3069-77 PubMed GONUTS page
↑ Emery, G et al. (2005) Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell 122 763-73 PubMed GONUTS page
↑ Jékely, G (2003) Small GTPases and the evolution of the eukaryotic cell. Bioessays 25 1129-38 PubMed GONUTS page
↑ Pelissier, A et al. (2003) Trafficking through Rab11 endosomes is required for cellularization during Drosophila embryogenesis. Curr. Biol. 13 1848-57 PubMed GONUTS page
↑ Shimizu, H et al. (2003) An essential role of Rab5 in uniformity of synaptic vesicle size. J. Cell. Sci. 116 3583-90 PubMed GONUTS page
↑ ^28.0 ^28.1 ^28.2 Dobie, KW et al. (2001) Identification of chromosome inheritance modifiers in Drosophila melanogaster. Genetics 157 1623-37 PubMed GONUTS page
↑ ^29.0 ^29.1 ^29.2 Entchev, EV et al. (2000) Gradient formation of the TGF-beta homolog Dpp. Cell 103 981-91 PubMed GONUTS page

[PMID:27064279-1] Xu, W et al. (2016) Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration. J. Clin. Invest. PubMed GONUTS page

[PMID:27253064-2] Lőrincz, P et al. (2016) MiniCORVET is a Vps8-containing early endosomal tether in Drosophila. Elife 5 PubMed GONUTS page

[PMID:12743108-3] 3.0 ^3.1 Wucherpfennig, T et al. (2003) Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J. Cell Biol. 161 609-24 PubMed GONUTS page

[PMID:20956291-4] 4.0 ^4.1 Hoopmann, P et al. (2010) Endosomal sorting of readily releasable synaptic vesicles. Proc. Natl. Acad. Sci. U.S.A. 107 19055-60 PubMed GONUTS page

[PMID:21873635-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 ^5.8 ^5.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:26265702-6] 6.0 ^6.1 Liu, G et al. (2015) Efficient Endocytic Uptake and Maturation in Drosophila Oocytes Requires Dynamitin/p50. Genetics 201 631-49 PubMed GONUTS page

[PMID:28420712-7] Wang, Y et al. (2017) Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of sensory neurons. Development 144 1851-1862 PubMed GONUTS page

[PMID:28482024-8] Inoshita, T et al. (2017) Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila. Hum. Mol. Genet. 26 2933-2948 PubMed GONUTS page

[PMID:25312435-9] Sakuma, C et al. (2014) Drosophila Strip serves as a platform for early endosome organization during axon elongation. Nat Commun 5 5180 PubMed GONUTS page

[PMID:19317464-10] Tan, DJ et al. (2009) Mapping organelle proteins and protein complexes in Drosophila melanogaster. J. Proteome Res. 8 2667-78 PubMed GONUTS page

[PMID:22825871-11] Chen, DY et al. (2012) The Bro1-domain-containing protein Myopic/HDPTP coordinates with Rab4 to regulate cell adhesion and migration. J. Cell. Sci. 125 4841-52 PubMed GONUTS page

[PMID:22648168-12] Jean, S et al. (2012) Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling. Mol. Biol. Cell 23 2723-40 PubMed GONUTS page

[PMID:22000105-13] 13.0 ^13.1 Chan, CC et al. (2011) Systematic discovery of Rab GTPases with synaptic functions in Drosophila. Curr. Biol. 21 1704-15 PubMed GONUTS page

[PMID:21729695-14] Lee, G et al. (2011) UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. Dev. Biol. 356 588-97 PubMed GONUTS page

[PMID:21533196-15] Mateus, AM et al. (2011) Endocytic and recycling endosomes modulate cell shape changes and tissue behaviour during morphogenesis in Drosophila. PLoS ONE 6 e18729 PubMed GONUTS page

[PMID:21149700-16] Assaker, G et al. (2010) Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. Proc. Natl. Acad. Sci. U.S.A. 107 22558-63 PubMed GONUTS page

[PMID:18758452-17] 17.0 ^17.1 Satoh, D et al. (2008) Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat. Cell Biol. 10 1164-71 PubMed GONUTS page

[PMID:18685079-18] 18.0 ^18.1 ^18.2 Morrison, HA et al. (2008) Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45. Mol. Biol. Cell 19 4167-76 PubMed GONUTS page

[PMID:19050045-19] 19.0 ^19.1 Compagnon, J et al. (2009) Interplay between Rab5 and PtdIns(4,5)P2 controls early endocytosis in the Drosophila germline. J. Cell. Sci. 122 25-35 PubMed GONUTS page

[PMID:19000840-20] 20.0 ^20.1 ^20.2 Wilkin, M et al. (2008) Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway. Dev. Cell 15 762-72 PubMed GONUTS page

[PMID:16258546-21] 21.0 ^21.1 Lu, H & Bilder, D (2005) Endocytic control of epithelial polarity and proliferation in Drosophila. Nat. Cell Biol. 7 1232-9 PubMed GONUTS page

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[PMID:16137758-24] Emery, G et al. (2005) Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell 122 763-73 PubMed GONUTS page

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[PMID:14588240-26] Pelissier, A et al. (2003) Trafficking through Rab11 endosomes is required for cellularization during Drosophila embryogenesis. Curr. Biol. 13 1848-57 PubMed GONUTS page

[PMID:12876219-27] Shimizu, H et al. (2003) An essential role of Rab5 in uniformity of synaptic vesicle size. J. Cell. Sci. 116 3583-90 PubMed GONUTS page

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