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DROME:Q9NIR4

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) CRC-A (ECO:0000313 with EMBL:AAF71698.1)
External Links
UniProt Q9NIR4
EMBL AF201924
AF201917
AF201918
AF201923
ProteinModelPortal Q9NIR4
PRIDE Q9NIR4
FlyBase FBgn0000370
Reactome REACT_180716
REACT_239200
REACT_93794
ChiTaRS Crc
crc
Bgee Q9NIR4
GO GO:0046982
GO:0001102
GO:0000980
GO:0001105
GO:0003700
GO:0007552
GO:0007591
GO:0045944
GO:0035073
GO:0035074
GO:0006355
GO:0042594
GO:0005991
GO:0006641
InterPro IPR004827
Pfam PF00170
SMART SM00338
PROSITE PS50217
PS00036

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2141857
MGI:MGI:88096
PANTHER:PTN000315883
WB:WBGene00013878

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2141857
MGI:MGI:88096
PANTHER:PTN000315883
RGD:621863
RGD:628902
UniProtKB:P18848
UniProtKB:Q9Y2D1
WB:WBGene00000221
WB:WBGene00013878

C

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88096
PANTHER:PTN000315883
UniProtKB:P18848
WB:WBGene00013878

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000315883
UniProtKB:Q9Y2D1

F

Seeded From UniProt

complete

involved_in

GO:0007591

molting cycle, chitin-based cuticle

PMID:10924469[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:10924469[2]

ECO:0000250

sequence similarity evidence used in manual assertion

protein_id:CAA43723.1

F

Seeded From UniProt

complete

involved_in

GO:0035073

pupariation

PMID:10924469[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035074

pupation

PMID:10924469[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007552

metamorphosis

PMID:10924469[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:22912598[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0001102

RNA polymerase II activating transcription factor binding

PMID:22912598[3]

ECO:0000353

physical interaction evidence used in manual assertion

FB:FBgn0000546

F

Seeded From UniProt

complete

enables

GO:0003713

transcription coactivator activity

PMID:22912598[3]

ECO:0000353

physical interaction evidence used in manual assertion

FB:FBgn0000546

F

Seeded From UniProt

complete

enables

GO:0003713

transcription coactivator activity

PMID:22912598[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:22912598[3]

ECO:0000305

curator inference used in manual assertion

GO:0003713,GO:0045944

C

Seeded From UniProt

complete

involved_in

GO:0005991

trehalose metabolic process

PMID:19690063[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042594

response to starvation

PMID:19690063[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006641

triglyceride metabolic process

PMID:19690063[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000980

RNA polymerase II distal enhancer sequence-specific DNA binding

PMID:16651547[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:16651547[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:10924469[2]

ECO:0000250

sequence similarity evidence used in manual assertion

protein_id:CAA43723.1

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004827

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004827

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Hewes, RS et al. (2000) The cryptocephal gene (ATF4) encodes multiple basic-leucine zipper proteins controlling molting and metamorphosis in Drosophila. Genetics 155 1711-23 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Gauthier, SA et al. (2012) Cryptocephal, the Drosophila melanogaster ATF4, is a specific coactivator for ecdysone receptor isoform B2. PLoS Genet. 8 e1002883 PubMed GONUTS page
  4. 4.0 4.1 4.2 Seo, J et al. (2009) Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes 58 2565-73 PubMed GONUTS page
  5. 5.0 5.1 Gauthier, SA & Hewes, RS (2006) Transcriptional regulation of neuropeptide and peptide hormone expression by the Drosophila dimmed and cryptocephal genes. J. Exp. Biol. 209 1803-15 PubMed GONUTS page