DICDI:PLDB

Species (Taxon ID)	Dictyostelium discoideum (Slime mold). (44689)
Gene Name(s)	pldB (synonyms: pld1)
Protein Name(s)	Phospholipase D B Phosphatase D1 PLD 1
External Links
UniProt	Q54WR4
EMBL	AAFI02000031
RefSeq	XP_641653.1
ProteinModelPortal	Q54WR4
STRING	44689.DDB_0231507
EnsemblProtists	DDB0231507
GeneID	8622060
KEGG	ddi:DDB_G0279483
dictyBase	DDB_G0279483
eggNOG	COG1502
InParanoid	Q54WR4
KO	K01115
OMA	FNISHRR
PhylomeDB	Q54WR4
Proteomes	UP000002195 UP000002195
GO	GO:0005938 GO:0016023 GO:0016020 GO:0043234 GO:0031143 GO:0005773 GO:0031982 GO:0005509 GO:0070290 GO:0004630 GO:0006928 GO:0043327 GO:0010467 GO:0016042 GO:0006644 GO:0045921 GO:2000249 GO:0060176
Gene3D	1.10.238.10 2.30.29.30
InterPro	IPR011992 IPR018247 IPR002048 IPR001849 IPR011993 IPR025202 IPR001736 IPR015679
PANTHER	PTHR18896
Pfam	PF00614 PF13091
SMART	SM00054 SM00233 SM00155
PROSITE	PS00018 PS50222 PS50003 PS50035

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
acts_upstream_of_or_within	GO:0048837	sorocarp sorus development	PMID:28257811^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004630	phospholipase D activity	PMID:20950684^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901263	positive regulation of sorocarp spore cell differentiation	PMID:20950684^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008277	regulation of G protein-coupled receptor signaling pathway	PMID:20950684^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009372	quorum sensing	PMID:20950684^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010467	gene expression	PMID:15821129^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	has_input:(UniProtKB:P13773)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000249	regulation of actin cytoskeleton reorganization	PMID:21531871^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045921	positive regulation of exocytosis	PMID:21531871^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043327	chemotaxis to cAMP	PMID:21531871^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
NOT\|acts_upstream_of_or_within	GO:0043326	chemotaxis to folate	PMID:21531871^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:21531871^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031982	vesicle	PMID:18164290^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031941	filamentous actin	PMID:21531871^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031143	pseudopodium	PMID:18164290^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q13393	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060176	regulation of aggregation involved in sorocarp development	PMID:15821129^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048870	cell motility	PMID:18164290^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:Q54S20	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048870	cell motility	PMID:18164290^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006644	phospholipid metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P36126	P		Seeded From UniProt	complete
part_of	GO:0005938	cell cortex	PMID:18164290^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005773	vacuole	PMID:16765443^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0048870	cell motility	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000431025 dictyBase:DDB_G0279483	P		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001736	F		Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002048	F		Seeded From UniProt	complete
enables	GO:0004630	phospholipase D activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.4.4	F		Seeded From UniProt	complete
enables	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.1.4.4	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
involved_in	GO:0016042	lipid catabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0442	P		Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
part_of	GO:0005938	cell cortex	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0138	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Singh, S et al. (2017) Functional interaction of PkcA and PldB regulate aggregation and development in Dictyostelium discoideum. Cell. Signal. 34 47-54 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Ray, S et al. (2011) Phospholipase D controls Dictyostelium development by regulating G protein signaling. Cell. Signal. 23 335-43 PubMed GONUTS page
↑ ^3.0 ^3.1 Chen, Y et al. (2005) PldB, a putative phospholipase D homologue in Dictyostelium discoideum mediates quorum sensing during development. Eukaryotic Cell 4 694-702 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Pribic, J et al. (2011) Paxillin and phospholipase D interact to regulate actin-based processes in Dictyostelium discoideum. Eukaryotic Cell 10 977-84 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 Nagasaki, A & Uyeda, TQ (2008) Screening of genes involved in cell migration in Dictyostelium. Exp. Cell Res. 314 1136-46 PubMed GONUTS page
↑ Thomason, PA et al. (2006) A series of Dictyostelium expression vectors for recombination cloning. Plasmid 56 145-52 PubMed GONUTS page
↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:28257811-1] Singh, S et al. (2017) Functional interaction of PkcA and PldB regulate aggregation and development in Dictyostelium discoideum. Cell. Signal. 34 47-54 PubMed GONUTS page

[PMID:20950684-2] 2.0 ^2.1 ^2.2 ^2.3 Ray, S et al. (2011) Phospholipase D controls Dictyostelium development by regulating G protein signaling. Cell. Signal. 23 335-43 PubMed GONUTS page

[PMID:15821129-3] 3.0 ^3.1 Chen, Y et al. (2005) PldB, a putative phospholipase D homologue in Dictyostelium discoideum mediates quorum sensing during development. Eukaryotic Cell 4 694-702 PubMed GONUTS page

[PMID:21531871-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Pribic, J et al. (2011) Paxillin and phospholipase D interact to regulate actin-based processes in Dictyostelium discoideum. Eukaryotic Cell 10 977-84 PubMed GONUTS page

[PMID:18164290-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 Nagasaki, A & Uyeda, TQ (2008) Screening of genes involved in cell migration in Dictyostelium. Exp. Cell Res. 314 1136-46 PubMed GONUTS page

[PMID:16765443-6] Thomason, PA et al. (2006) A series of Dictyostelium expression vectors for recombination cloning. Plasmid 56 145-52 PubMed GONUTS page

[PMID:21873635-7] Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

DICDI:PLDB

Contents

Annotations

Notes

References

a

c

d

e

f

g

h

l

m

n

o

p

q

r

s

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools