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DICDI:HD
Contents
| Species (Taxon ID) | Dictyostelium discoideum (Slime mold). (44689) | |
| Gene Name(s) | htt (synonyms: hd) | |
| Protein Name(s) | HD protein homolog | |
| External Links | ||
| UniProt | Q76P24 | |
| EMBL | AAFI02000008 | |
| RefSeq | XP_645159.1 | |
| ProteinModelPortal | Q76P24 | |
| STRING | 44689.DDBDRAFT_0206578 | |
| PRIDE | Q76P24 | |
| EnsemblProtists | DDB0238473 | |
| GeneID | 8618330 | |
| KEGG | ddi:DDB_G0272344 | |
| dictyBase | DDB_G0272344 | |
| eggNOG | NOG82191 | |
| InParanoid | Q76P24 | |
| KO | K04533 | |
| OMA | TISEQIC | |
| PRO | PR:Q76P24 | |
| Proteomes | UP000002195 UP000002195 | |
| GO | GO:0005737 GO:0005634 GO:0016339 GO:0030154 GO:0043327 GO:0007109 GO:0072507 GO:0006971 GO:0060176 GO:0043520 GO:0034047 GO:0031156 GO:0006810 | |
| Gene3D | 1.25.10.10 | |
| InterPro | IPR011989 IPR016024 IPR028426 | |
| PANTHER | PTHR10170 | |
| SUPFAM | SSF48371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
acts_upstream_of_or_within |
GO:0035864 |
response to potassium ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0006935) |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0051592 |
response to calcium ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0006935) |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0006412 |
translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_output:(UniProtKB:P08796) |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1902463 |
protein localization to cell leading edge |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_input:(UniProtKB:Q552S0) |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0006935 |
chemotaxis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0072507 |
divalent inorganic cation homeostasis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0060176 |
regulation of aggregation involved in sorocarp development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0060176 |
regulation of aggregation involved in sorocarp development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0043520 |
regulation of myosin II filament assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0043327 |
chemotaxis to cAMP |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0043666 |
regulation of phosphoprotein phosphatase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0031156 |
regulation of sorocarp development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030154 |
cell differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0016339 |
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0061952 |
midbody abscission |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0006971 |
hypotonic response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Wessels, D et al. (2014) Huntingtin regulates Ca(2+) chemotaxis and K(+)-facilitated cAMP chemotaxis, in conjunction with the monovalent cation/H(+) exchanger Nhe1, in a model developmental system: insights into its possible role in Huntington׳s disease. Dev. Biol. 394 24-38 PubMed GONUTS page
- ↑ Thompson, MN et al. (2014) Huntingtin Supplies a csaA-Independent Function Essential for EDTA-Resistant Homotypic Cell Adhesion in Dictyostelium discoideum. J Huntingtons Dis 3 261-71 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Myre, MA et al. (2011) Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum. PLoS Genet. 7 e1002052 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Wang, Y et al. (2011) Dictyostelium huntingtin controls chemotaxis and cytokinesis through the regulation of myosin II phosphorylation. Mol. Biol. Cell 22 2270-81 PubMed GONUTS page
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