GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PMID:25300330

From GONUTS
Jump to: navigation, search
Citation

Thompson, MN, MacDonald, ME, Gusella, JF and Myre, MA (2014) Huntingtin Supplies a csaA-Independent Function Essential for EDTA-Resistant Homotypic Cell Adhesion in Dictyostelium discoideum. J Huntingtons Dis 3:261-71

Abstract

The CAG triplet repeat expansion mutation in the HTT locus, which results in neurodegeneration in Huntington's disease, elongates a polyglutamine tract in huntingtin, a HEAT/HEAT-like protein that has been highly structurally conserved through evolution. In several organisms, huntingtin is necessary for proper cell-cell adhesion and normal development.

Links

PubMed Online version:10.3233/JHD-140112

Keywords


Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

DICDI:HD

acts_upstream_of_or_within

GO:0006412: translation

ECO:0000315: mutant phenotype evidence used in manual assertion

P

  • has_output:(UniProtKB:P08796)

Seeded From UniProt

complete

DICDI:HD

acts_upstream_of_or_within

GO:0006412: translation

ECO:0000315: mutant phenotype evidence used in manual assertion

P

has_output:(UniProtKB:P08796)

Seeded From UniProt

complete

Notes

See also

References

See Help:References for how to manage references in GONUTS.