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Category:Team Hardy Weinburgers

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptablePIG:I3L6Y9Vvg0009, Team Hardy Weinburgers2015-11-03 16:01:11 CSTGO:0039537 suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway (P)PMID:26512690ECO:0000314 direct assay evidence used in manual assertion

Figures 2 and 3 shows that Dicer is normally involved in the cellular defense against viruses. The expression of Dicer is shown in Figure 2 when the cell is placed under viral stress, and in Figure 3, the levels of the fragment of the porcine reproductive and respiratory syndrome virus (PRRSV) is shown to be lowered in the presence of Dicer. However, in Figure 1, PRRSV is shown to silence luciferase when gene that codes for luciferase is placed in the gene that codes for Dicer. In Figure 4, the PRRSV lowers the expression of Dicer and Ago-2 (both involved in the cellular defense mechanism against PRRSV) simultaneously when fully functional. The lowered expression is shown specifically in Figure 4.F.

challenge
updatedbyinstructor9LACT:Q79AF8Christin3sheets, Team Hardy Weinburgers2015-11-03 15:19:45 CSTGO:0015366 malate:proton symporter activity (F)PMID:9218448ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3B & 3C

challenge
unacceptableLACLL:CITNChristin3sheets, Team Hardy Weinburgers2015-11-03 15:12:05 CSTGO:0015366 malate:proton symporter activity (F)PMID:9218448ECO:0000250 sequence similarity evidence used in manual assertion

Figure 1: alignment of primary sequences of protein Mlep (which functions in transmembrane malate transport) and CitP, to show that CitP functions similarly in transmembrane citrate transport.

challenge
updatedbyinstructorBACSU:CIMHChristin3sheets, Team Hardy Weinburgers2015-11-03 14:58:47 CSTGO:0015531 citrate:proton symporter activity (F)PMID:11566984ECO:0000314 direct assay evidence used in manual assertion

Figure 2A, 3 - shows that production of the gene product CimHbs due to the normal function of the CimH gene causes greater catalysis of citrate and malate uptake.

challenge
updatedbyinstructorBACSU:MLENChristin3sheets, Team Hardy Weinburgers2015-11-03 14:16:02 CSTGO:0015385 sodium:proton antiporter activity (F)PMID:10903309ECO:0000314 direct assay evidence used in manual assertion

Figure 5

challenge
updatedbyinstructorBACSU:MRPFChristin3sheets, Team Hardy Weinburgers2015-11-03 13:39:41 CSTGO:0036376 sodium ion export from cell (P)PMID:11004162ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5

challenge
updatedbyinstructorBACCE:GERNChristin3sheets, Team Hardy Weinburgers2015-10-20 16:13:17 CDTGO:0015385 sodium:proton antiporter activity (F)PMID:11566988ECO:0000314 direct assay evidence used in manual assertion

Figure 3 - Double reciprocal plot of NaCl concentration vs percent dequenching in the AO fluorescence assay.

challenge
updatedbyinstructorMOUSE:STK4Vvg0009, Team Hardy Weinburgers2015-10-20 13:50:25 CDTGO:1904237 positive regulation of substrate-dependent cell migration, cell attachment to substrate (P)PMID:19073936ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4

challenge
updatedbyinstructorARATH:SCL23Vvg0009, Team Hardy Weinburgers2015-10-20 13:40:17 CDTGO:0001714 endodermal cell fate specification (P)PMID:26415082ECO:0000316 genetic interaction evidence used in manual assertion

SCL23 works with SCR to regulate endodermal cell fate. This is shown in Figure 2 where the mutant lacking SCL23 can differentiate cells to a certain extent.

challenge
updatedbyinstructorSTAA8:Q2G0W2Christin3sheets, Team Hardy Weinburgers2015-09-22 17:14:02 CDTGO:0019646 aerobic electron transport chain (P)PMID:25448817ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7 - Oxygen consumption rates decreased in MpsA and MpsABC mutants, but increased in MpsA containing cells.

challenge
updatedbyinstructorSTAA3:Y844Christin3sheets, Team Hardy Weinburgers2015-09-22 17:14:01 CDTGO:0050136 NADH dehydrogenase (quinone) activity (F)PMID:25448817ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 6B

challenge
updatedbyinstructorSTAA8:Q2G0W2Christin3sheets, Team Hardy Weinburgers2015-09-22 17:14:01 CDTGO:0045838 positive regulation of membrane potential (P)PMID:25448817ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5A

challenge
unacceptableSTAA8:Q2G0W2Christin3sheets, Team Hardy Weinburgers2015-09-21 19:23:32 CDTGO:0016491 oxidoreductase activity (F)PMID:25448817ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7

challenge
updatedbyinstructorSTAA8:Q2G0W2Christin3sheets, Team Hardy Weinburgers2015-09-21 19:23:32 CDTGO:0005887 integral component of plasma membrane (C)PMID:25448817ECO:0000250 sequence similarity evidence used in manual assertion

Figure 2; there was an alignment done to E. coli NuoL (accession no. P33607) and a TMHMM.

challenge

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Pages in category "Team Hardy Weinburgers"

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