GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
|Status||Page||User||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|MOUSE:GTR2||Cheem005, Team Cacao||2012-02-26 12:07:11 CST||GO:0015755 fructose transport (P)||other:PMC2343460||ECO:0000315 mutant phenotype evidence used in manual assertion|
Table 2 shows that glycaemia was lower in GLUT2-null mice on high fructose diet.
|HUMAN:AHSP||Cheem005, Team Cacao||2012-02-26 10:43:38 CST||GO:0051082 unfolded protein binding (F)||other:PMC2878560||ECO:0000315 mutant phenotype evidence used in manual assertion|
Figure 4 shows the thermal unfolding curve of the wild type, isolated and the mutant AHSP protein
|HUMAN:HBA||Cheem005, Team Cacao||2012-02-26 10:28:41 CST||GO:0005515 protein binding (F)||other:PMC2700329||ECO:0000315 mutant phenotype evidence used in manual assertion|
Table 1 shows how different mutations affect it coming in contact with AHSP and beta globin.
|MOUSE:JKAMP||Cheem005, Team Cacao||2012-02-12 13:58:38 CST||GO:0016020 membrane (C)||PMID:16166642||ECO:0000314 direct assay evidence used in manual assertion|
|?||Cheem005, Team Cacao||2012-02-12 11:58:47 CST||GO:0030240 skeletal muscle thin filament assembly (There is only a small amino acid difference in the mutant protein. Isoleucine 357 to Leucine but they result in a lethal phenotype. Molecular modeling of this mutation highlights potential alterations in hydrogen bonding at the extreme C-terminus of G-actin. Fig. 8)||PMID:15198992||IMP: Inferred from Mutant Phenotype||challenge|
|?||Cheem005, Team Cacao||2012-02-12 11:22:27 CST||GO:0030017 sarcomere (There are less contraction in the sarcomeres of the mouse with mutant gene. Fig 2)||PMID:22174871||IMP: Inferred from Mutant Phenotype||challenge|