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Category:Team Cacao

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
requireschangesMOUSE:GTR2Cheem005, Team Cacao2012-02-26 12:07:11 CSTGO:0015755 fructose transport (P)other:PMC2343460ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2 shows that glycaemia was lower in GLUT2-null mice on high fructose diet.

challenge
requireschangesHUMAN:AHSPCheem005, Team Cacao2012-02-26 10:43:38 CSTGO:0051082 unfolded protein binding (F)other:PMC2878560ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4 shows the thermal unfolding curve of the wild type, isolated and the mutant AHSP protein

challenge
requireschangesHUMAN:HBACheem005, Team Cacao2012-02-26 10:28:41 CSTGO:0005515 protein binding (F)other:PMC2700329ECO:0000315 mutant phenotype evidence used in manual assertion

Table 1 shows how different mutations affect it coming in contact with AHSP and beta globin.

challenge
requireschangesMOUSE:JKAMPCheem005, Team Cacao2012-02-12 13:58:38 CSTGO:0016020 membrane (C)PMID:16166642ECO:0000314 direct assay evidence used in manual assertion

Fig 3

challenge
requireschanges?Cheem005, Team Cacao2012-02-12 11:58:47 CSTGO:0030240 skeletal muscle thin filament assembly (There is only a small amino acid difference in the mutant protein. Isoleucine 357 to Leucine but they result in a lethal phenotype. Molecular modeling of this mutation highlights potential alterations in hydrogen bonding at the extreme C-terminus of G-actin. Fig. 8)PMID:15198992IMP: Inferred from Mutant Phenotype
challenge
requireschanges?Cheem005, Team Cacao2012-02-12 11:22:27 CSTGO:0030017 sarcomere (There are less contraction in the sarcomeres of the mouse with mutant gene. Fig 2)PMID:22174871IMP: Inferred from Mutant Phenotype
challenge

Pages in category "Team Cacao"

The following 2 pages are in this category, out of 2 total.


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