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HUMAN:AHSP

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) AHSP (synonyms: EDRF, ERAF)
Protein Name(s) Alpha-hemoglobin-stabilizing protein

Erythroid differentiation-related factor Erythroid-associated factor

External Links
UniProt Q9NZD4
EMBL AF364517
AF208865
AY072612
AF485325
BC035842
CCDS CCDS10716.1
RefSeq NP_057717.1
XP_005255408.1
XP_005255409.1
UniGene Hs.274309
PDB 1W09
1W0A
1W0B
1XZY
1Y01
1Z8U
3IA3
3OVU
PDBsum 1W09
1W0A
1W0B
1XZY
1Y01
1Z8U
3IA3
3OVU
ProteinModelPortal Q9NZD4
SMR Q9NZD4
BioGrid 119476
IntAct Q9NZD4
MINT MINT-1427628
STRING 9606.ENSP00000307199
DMDM 23813669
PaxDb Q9NZD4
PeptideAtlas Q9NZD4
PRIDE Q9NZD4
DNASU 51327
Ensembl ENST00000302312
GeneID 51327
KEGG hsa:51327
UCSC uc002ecj.3
CTD 51327
GeneCards GC16P031540
HGNC HGNC:18075
HPA HPA040940
MIM 605821
neXtProt NX_Q9NZD4
PharmGKB PA27842
eggNOG NOG42947
GeneTree ENSGT00390000003648
HOGENOM HOG000030915
HOVERGEN HBG023495
InParanoid Q9NZD4
OMA GMKEFNV
OrthoDB EOG7TF7CW
PhylomeDB Q9NZD4
TreeFam TF337056
ChiTaRS AHSP
EvolutionaryTrace Q9NZD4
GeneWiki ERAF
GenomeRNAi 51327
NextBio 54729
PRO PR:Q9NZD4
Proteomes UP000005640
Bgee Q9NZD4
CleanEx HS_ERAF
ExpressionAtlas Q9NZD4
Genevestigator Q9NZD4
GO GO:0005833
GO:0030492
GO:0051082
GO:0020027
GO:0030097
GO:0006457
GO:0050821
Gene3D 1.20.58.420
InterPro IPR015317
PANTHER PTHR15914
Pfam PF09236
ProDom PD285427
SUPFAM SSF109751

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0051082

unfolded protein binding

other:PMC2878560

ECO:0000315

F

Figure 4 shows the thermal unfolding curve of the wild type, isolated and the mutant AHSP protein

complete
CACAO 3847

enables

GO:0051082

unfolded protein binding

PMID:12066189[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

PMID:12066189[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030097

hemopoiesis

PMID:12066189[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0020027

hemoglobin metabolic process

PMID:12066189[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005833

hemoglobin complex

PMID:12066189[1]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0050821

protein stabilization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2158492
PANTHER:PTN000408386

P

Seeded From UniProt

complete

involved_in

GO:0030218

erythrocyte differentiation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2158492
PANTHER:PTN000408386

P

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2158492
PANTHER:PTN000408386

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2158492
PANTHER:PTN000408386

C

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015317

P

Seeded From UniProt

complete

involved_in

GO:0030218

erythrocyte differentiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015317

P

Seeded From UniProt

complete

enables

GO:0030492

hemoglobin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015317

F

Seeded From UniProt

complete

involved_in

GO:0050821

protein stabilization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015317

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Kihm, AJ et al. (2002) An abundant erythroid protein that stabilizes free alpha-haemoglobin. Nature 417 758-63 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page