GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0097411 ! hypoxia-inducible factor-1alpha signaling pathway
name: hypoxia-inducible factor-1alpha signaling pathway
namespace: biological_process
def: "The series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia." [GOC:bf, GOC:jc, PMID:16887934, PMID:26579469]
synonym: "HIF1alpha pathway" EXACT []
synonym: "hypoxia-inducible factor signaling" EXACT [GOC:bf]
synonym: "hypoxia-inducible factor-1alpha signalling pathway" EXACT []
is_a: GO:0035556 ! intracellular signal transduction
relationship: part_of: GO:0071456 ! cellular response to hypoxia
AmiGO
<GOterm>GO:0097411</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
Child Terms
This category has the following 2 subcategories, out of 2 total.
