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Category:GO:0071596 ! ubiquitin-dependent protein catabolic process via the N-end rule pathway
name: ubiquitin-dependent protein catabolic process via the N-end rule pathway
namespace: biological_process
def: "The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation." [GOC:mah, GOC:rb, PMID:19246002, PMID:9112437]
synonym: "ubiquitin-dependent protein breakdown via the N-end rule pathway" EXACT [GOC:mah]
synonym: "ubiquitin-dependent protein catabolism via the N-end rule pathway" EXACT [GOC:mah]
synonym: "ubiquitin-dependent protein degradation via the N-end rule pathway" EXACT [GOC:mah]
is_a: GO:0043161 ! proteasome-mediated ubiquitin-dependent protein catabolic process
AmiGO
<GOterm>GO:0071596</GOterm>
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