name: NEDD8 ligase activity
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def: "Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate." [GOC:dph]
synonym: "E3" RELATED [GOC:dph]
is_a: GO:0019788 ! NEDD8 transferase activity
is_a: GO:0061659 ! ubiquitin-like protein ligase activity
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Pages in category "GO:0061663 ! NEDD8 ligase activity"
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