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Category:GO:0045254 ! pyruvate dehydrogenase complex
name: pyruvate dehydrogenase complex
def: "Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3)." [ISBN:0716720094]
comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.
synonym: "dihydrolipoyl dehydrogenase complex" BROAD 
synonym: "pyruvate dehydrogenase complex (lipoamide)" EXACT 
is_a: GO:1990204 ! oxidoreductase complex
relationship: part_of: GO:0005737 ! cytoplasm
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This category has the following 3 subcategories, out of 3 total.
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