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Category:GO:0043564 ! Ku70:Ku80 complex
id: GO:0043564
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name: Ku70:Ku80 complex
namespace: cellular_component
def: "Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK." [PMID:12518983]
synonym: "Ku70:Ku80 heterodimer" EXACT []
is_a: GO:0140513 ! nuclear protein-containing complex
AmiGO
<GOterm>GO:0043564</GOterm>
Gene Ontology Home
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Usage Notes
References
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